Conserved Protein Domain Family
pRN1_helical

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pfam13010: pRN1_helical 
Primase helical domain
This alpha helical domain is found in a set of bacterial plasmid replication proteins. The domain is found to the C-terminus of the primase/polymerase domain. Mutants of this domain are defective in template binding, dinucleotide formation and conformation change prior to DNA extension.
Statistics
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PSSM-Id: 289758
Aligned: 2 rows
Threshold Bit Score: 240.786
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q973E3 215 VKKED--EKLEKLKEEMAKYDRFKGKTVEAIREEVCKEISKELEELkgkdDKKSKKwsaILTTAESAVCEGKTYAEIGID 292 Sulfurisphaera tokodaii
Q980Y0 217 NKKSDteEDFEKLKEEMRKYDRYRGKTLDAIRDELCKAIKKKIEHA----EEKAKE---TLNIAKGVLCDKKTYADIGID 289 Saccharolobus solfata...
Q973E3 293 RSRGDWAFYYVLFSHGATNLDVLEQLLPSDSKVFAPKWDKYYVHTVKKVWEKVKPLLE 350 Sulfurisphaera tokodaii
Q980Y0 290 RSRGDWHLLNFLLSHGATDLDVVMQLLPEDSKVFEPKWDKYTFHTVAKIWERVKPWLT 347 Saccharolobus solfataricus
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