Conserved Protein Domain Family
BACON

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pfam13004: BACON (This model is not part of the current CDD release)
Putative binding domain, N-terminal
The BACON (Bacteroidetes-Associated Carbohydrate-binding Often N-terminal) domain is an all-beta domain found in diverse architectures, principally in combination with carbohydrate-active enzymes and proteases. These architectures suggest a carbohydrate-binding function which is also supported by the nature of BACON's few conserved amino-acids. The phyletic distribution of BACON and other data tentatively suggest that it may frequently function to bind mucin. Further work with the characterised structure of a member of glycoside hydrolase family 5 enzyme, PDB:3ZMR, has found no evidence for carbohydrate-binding for this domain.
Statistics
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PSSM-Id: 520559
Aligned: 187 rows
Threshold Bit Score: 25.8755
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_013546542  141 TVT-----VTAnveydiqmpkdqeWITQEAATKAlVDy--------DHAF-RISPNKTFES-RT-AQISFIAKQDPE--- 201  Bacteroides h...
51_pfamImport   1 AGT-----TD--------------WCTV-------TQnsgd--gsaSVGI-RVSANT-TKLeRS-TTLTIVGGPLSSt-- 47  
Q8A1V0         61 GKW-----TASsq---------dsWCTINNKEGNgNA---------STIC-SVSANDDDE--RY-TVITVTSNGKSEn-- 111  Bacteroides t...
13_pfamImport   1 YIQndearS---------------WVTV-------TPsageeagehTVQI-LLDENT-TGNpRT-VRIDLNC----Qsqt 51  
Q89ZT1         68 DRW-----SAQsn---------aeWCKVVQHEG-------------KVVV-SASANNIYKQ-RR-AEITVAYGHQSYs-- 115  Bacteroides t...
CDD82310       65 QVV-----CRTeg---------tdWVRAFPDEGDkDG---------HFNL-IVSANSGFQA-RQ-AEFALVVGEQEYpi- 117 
AGY53612       68 WKI-----VANse---------dtWAKFFPNEGDdDG---------IVKV-IVAENKTFVS-RE-MKFAFVVDGEEQpv- 120 
CDE57826      169 IPF-----SATss---------aeWCNVTIGSTLeQPyl-----tdAVSIdILPSNSTKD--ET-ATVSLTTLYGKTt-- 224 
CDA76953       58 MNW-----SLSss---------aiWCKLVQGDNT-AFvlngaagkqTVKV-KLTADEESKD-MSvAQLYLTMGGQK---- 116 
WP_021981299  159 TLA-----FKGea---------paWVRLADGAATsGRag-----kyTVHY-QLDQNTTTAE-RT-AVLELKSRGVSTd-- 214  Paraprevotella
WP_013546542  202 --VKaictIVQA 211  Bacteroides helcogenes
51_pfamImport  48 --IV----VTQK 53  
Q8A1V0        112 --IT----ITQK 117  Bacteroides thetaiotaomicron
13_pfamImport  52 etIT----INQE 59  
Q89ZT1        116 --IT----VSQF 121  Bacteroides thetaiotaomicron
CDD82310      118 -lLC----VNQA 124 
AGY53612      121 -lFT----VTQA 127 
CDE57826      225 -tIT----ITRR 231 
CDA76953      117 --IS----IAEV 122 
WP_021981299  215 --IR----IKQL 220  Paraprevotella
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