Conserved Protein Domain Family
Fer4_7
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pfam12838: Fer4_7 (This model is not part of the current CDD release)
4Fe-4S dicluster domain
Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich. Domain contains two 4Fe4S clusters.
Links
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Statistics
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PSSM-Id: 520485
Aligned: 153 rows
Threshold Bit Score: 28.2563
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q7UIA0         985 RCIGTR-----YCANNC------------------------------------------------P-YKVRRFN------ 1004 Pirellula sp.
WP_012301895     9 KCDGCRnereaLCELIC------------------------------------------------P-GNLMALD------ 33   Candidatus D...
WP_015758977     9 KCDGCKgqdktACMYIC------------------------------------------------P-NDLMVLD------ 33   Desulfofarci...
WP_012302957     9 KCDGCQgeqepLCELVC------------------------------------------------P-GNLMVIQ------ 33   Candidatus D...
WP_014960248     9 ACHGCTklpeaRCVTAC------------------------------------------------P-GDLIGIR------ 33   Leptospirillum
WP_015481790   767 SCTGCG-----ACVVAChaennvpvvgkrevrvgrdmhwlridryysstvetredakelglsrgeM-YEALET------- 833  Polaribacter...
11_pfamImport    1 ACIGCN-----ACVIAC------------------------------------------------QsENNIAVV------ 21  
Q32FA0          62 RCNGCN-----ICARACrkt------------------------------------------nhvP------AQgsrlsi 88   Shigella dys...
Q39RB4          10 LCTRCG-----ACVATC------------------------------------------------P-ARIIELP------ 29   Geobacter me...
Q6ANI9          10 RCNKCG-----ACAMDC------------------------------------------------P-ASIIEIQ------ 29   Desulfotalea...

Q7UIA0        1005 ---YFNYNKevgvgygidA---YpgsiekanrklqqlvlnpdvtvrgR-GVMEKCTYCvqriehakidarkdggrpvrdg 1077 Pirellula sp.
WP_012301895    34 ---TETNK----------G---Y------------------------C-RSPRDCWDC---------------------- 50   Candidatus D...
WP_015758977    34 ---KE-------------KmkaY------------------------N-RDLTACWEC---------------------- 50   Desulfofarci...
WP_012302957    34 ---EHT------------Gk-aV------------------------C-RDVGDCWDC---------------------- 50   Candidatus D...
WP_014960248    34 ---EDrk--------------aY------------------------M-RVQADCWDC---------------------- 49   Leptospirillum
WP_015481790   834 -------EA---------EnpeV------------------------T-FQPMMCQHC---------------------- 850  Polaribacter...
11_pfamImport   22 ---GKKNVRnsr----emH---Wlridtyfs--------geasnphtF-YQPMMCQHC---------------------- 60  
Q32FA0          89 ahiPVTDND---------NetqY------------------------H-FFRQSCQHC---------------------- 112  Shigella dys...
Q39RB4          30 ---K--------------GvprF------------------------TaTGEARCIIC---------------------- 46   Geobacter me...
Q6ANI9          30 ---ADFPr-------------vF------------------------P-YNEESCYQC---------------------- 46   Desulfotalea...

Q7UIA0        1078 eivTA--CQAACPTNA 1091 Pirellula sp.
WP_012301895    51 ---MS--CTKICPKGA 61   Candidatus Desulforudis audaxviator
WP_015758977    51 ---LC--CVKICPQQA 61   Desulfofarcimen acetoxidans
WP_012302957    51 ---MT--CTKSCPRQA 61   Candidatus Desulforudis audaxviator
WP_014960248    50 ---YA--CVKMCPVSA 60   Leptospirillum
WP_015481790   851 ---NHapCETVCPVAA 863  Polaribacter sp. MED152
11_pfamImport   61 ---ERapCEYVCPVAA 73  
Q32FA0         113 ---EDapCIDVCPTGA 125  Shigella dysenteriae Sd197
Q39RB4          47 ---GH--CEAVCPTAA 57   Geobacter metallireducens GS-15
Q6ANI9          47 ---EH--CLAICPTAA 57   Desulfotalea psychrophila
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