4RFS,4HUQ


Conserved Protein Domain Family
ECF_trnsprt
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pfam12822: ECF_trnsprt (This model is not part of the current CDD release)
ECF transporter, substrate-specific component
Energy-coupling factor (ECF) transporters consist of a substrate-specific component (known as the S component), and an energy-coupling module. The substrate-binding component is a small integral membrane protein which captures specific substrates and forms an active transporter in the presence of the energy-coupling AT module.
Links
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Statistics
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PSSM-Id: 520475
Aligned: 43 rows
Threshold Bit Score: 39.9831
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4RFS_S          8 RL--------------VVDALLMAIVLLQNlvp-flgYIPFGPF--------S-MTLIGLTVIv--aGSALGPRDGLLIG 61  Levilactobacil...
Q67N27         65 TL--------------VRLGILLALSVLGA-------YIKLGp---------SsIAFDAMAGFv--aALLMGPAAGALIC 112 Symbiobacteriu...
WP_012574692    3 RF--------------TLLVMFISLSVIGSl-----iKIPFTIG--------S-IALDSAPAVv--aAVLLGPTAAAVVA 52  Anoxybacillus ...
WP_012160051   14 VI--------------TRSGLLIGLSAIGA-------MIKIQ----------GtIAFDSMPGFf--aALFISPMAGGAVA 60  Alkaliphilus o...
Q8RCP1         13 TL--------------TLVAMLIALSAVGA-------LIKIF----------NtVAFDSMPGYf--aALYLGSLYGAIVI 59  Caldanaerobact...
Q895F2          9 KL--------------IRASLLLALAIIAQglgrsfpQISQLFV----------GSIVNCILIi--sALTCSTYLGILVG 62  Clostridium te...
jgi:Cthe_2981  20 YL--------------TRTAMLLALTVIFQfigrfipLGPNSNF----------IVGPLVNACliisAGLVGLFSGTVIS 75 
Q98QR5         32 FVnylknefrfttfdiAISGILFALSLVSSliv-hhtLPPRLNI--------D-TEILFFITF----GIFFGPIKGVFLS 97  Mycoplasma pul...
WP_011953602   15 NL--------------TLAAMLIALQVILN------------KLsigdpavlK-FSFGFIATAl--iGYCLGPWIGGWSM 65  Limosilactobac...
Q03S56         16 SM--------------VTMGVLMALQLVIS------------RFsvgn-nfiK-VSFTFLIVAl--iAKWFGPWWGMLTA 65  Lactobacillus ...

4RFS_S         62 GFWGLITFVraFtWPSSPVa--pLIFtnplisILPRLLMGLVAGsly----lwgRHRQWSM------------------- 116 Levilactobacil...
Q67N27        113 GLGHVAVAA--V-----------TGF------PLTLPFHLASAAamagvgclggLAARRFGl------------------ 155 Symbiobacteriu...
WP_012574692   53 SVGHVVSAL--F------------GG------FPLGPFHILVAIemaallyivgLLIRRGWf------------------ 94  Anoxybacillus ...
WP_012160051   61 SLGHLLTAF--T-----------SGF------PLTLPMHLMLTVvmgiiayffgVIERKVNg------------------ 103 Alkaliphilus o...
Q8RCP1         60 ALGHLLTAV--T-----------SGF------PLGVLNHLYIALqmavyaylfrVFYKKFNv------------------ 102 Caldanaerobact...
Q895F2         63 GLTPILAWV--IgQLPAPMasfvPFI------AIGNGIYIILFAliy----kreQSSRK--------------------- 109 Clostridium te...
jgi:Cthe_2981  76 VLAPYGAIL--TgATLPLPl--aPFV------ALGNFVLVLAFY------------IFRKKk------------------ 115
Q98QR5         98 IITDTFALI--L-KGRIAFw--mWEY------AISAVFIPIIASlly----qiyKNKNLKLifipitiivvsltggfttf 162 Mycoplasma pul...
WP_011953602   66 VVSDIISNT--IlNSGSLFf---PGF------TLSAFIAGVIAGmfl-----yqQRISWQRi------------------ 111 Limosilactobac...
Q03S56         66 AVVDVIGTL--MtGGPFF-----IGF------TVSAVLGSLIYAvfl-----yrQPVSWWRv------------------ 109 Lactobacillus ...

4RFS_S        117 ---------------RQAMQVAAGCAALTNTVL-VLGLV---FLFYQtpavata-------------------------- 151 Levilactobacil...
Q67N27        156 ---------------VAGAAVLVVANGILAPAL-LALLP---NPLGL--------------------------------- 183 Symbiobacteriu...
WP_012574692   95 ---------------IFSYVCFFIGNALLAPLP-FVWIMs---------------------------------------- 118 Anoxybacillus ...
WP_012160051  104 ---------------VLACVIAILLNGPVATFIaGITASllgLPLSGs-------------------------------- 136 Alkaliphilus o...
Q8RCP1        103 ---------------YVAIVLTTLLNGPLATLLf--------VPMFGw-------------------------------- 127 Caldanaerobact...
Q895F2        110 ---------------YLSVVVASIFKYFFLFLS-SSKLI---YLFSLnipk----------------------------- 141 Clostridium te...
jgi:Cthe_2981 116 ---------------VAGIIAGSIAKFAVIYG--SLLYI---IPFFKllpqn---------------------------- 147
Q98QR5        163 afyrpkkgvdiwiwqEVSFISSIVVSTIVALVS-LILIF---LFLFLylktkkdiyfriiiviclivssvvlsrwlmgpy 238 Mycoplasma pul...
WP_011953602  112 ---------------LIYEFFQILLTNVIGTTL-WLYLMslsSSSTG--------------------------------- 142 Limosilactobac...
Q03S56        110 ---------------IGASVLIALLVNTLLNTL-WVTIMy---------------------------------------- 133 Lactobacillus ...

4RFS_S        152 ------------fgatgnqTLGYVLMISLFTNGIPELILDVLVAPLIA 187 Levilactobacillus brevis
Q67N27        184 -------------------GLFAALALPLTVAAGANAAVALLVVLGLR 212 Symbiobacterium thermophilum
WP_012574692  119 ------------------pAFVLSIIPPLALATGVNLAIAVVVSKALQ 148 Anoxybacillus flavithermus
WP_012160051  137 -------------------AMFTALVIPLTVVAAVNVILAYIIFKVLP 165 Alkaliphilus oremlandii
Q8RCP1        128 -------------------GFFITWVFPLTIASFINISLAALIYKILS 156 Caldanaerobacter subterraneus subsp. tengconge...
Q895F2        142 ---------------kvaeKLVIMMGFPQLMTALIGGALALVLYEVLI 174 Clostridium tetani
jgi:Cthe_2981 148 ---------------kamaLAGAAFGWPQLVTALIGGIIAIPVVHRLE 180
Q98QR5        239 aftnylnrflpskrvrlhkDLYFTWQGPIIIKSLFTIPIYSLILVPLI 286 Mycoplasma pulmonis
WP_011953602  143 -------------------HTFMALLFIRLPKELITWPIETLLVLVIL 171 Limosilactobacillus reuteri
Q03S56        134 ------------------qTPFWSLLPVRALKELIVTPVQIVLVYLLL 163 Lactobacillus brevis ATCC 367
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