Conserved Protein Domain Family
Fer4_5

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pfam12801: Fer4_5 (This model is not part of the current CDD release)
4Fe-4S binding domain
Superfamily includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. Structure of the domain is an alpha-antiparallel beta sandwich.
Statistics
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PSSM-Id: 520461
Aligned: 101 rows
Threshold Bit Score: 34.0778
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
jgi:Dred_0490  40 AGFLLLLCMIGAVGMSFF-SGRSWCDWMCPRGAFYDVFFQ------KFNQGKP 85 
WP_011832976  250 FAGLGFAGLVALLVITYF-FGRVFCAHMCPAGVLQELLYRi----pVKKVQIK 297 Methanocorpusculum labreanum
WP_012499188   44 WAVLGLLFWGGLVFAAVR-SGKWVCVSICWLGGIQDLMYRw----aKKRVNFS 91  Chloroherpeton thalassium
Q39QC6        207 LSGIPLAVIAVLLVLSLP-VRNPFCRYLCPYGALLGLVSVl----sPVKVTRE 254 Geobacter metallireducens GS-15
Q6LZD9        138 NGTVISFILLGLFIILGYfIPMFFCRYFCPIGALLGLLSVk----pVFKIKSN 186 Methanococcus maripaludis
P52636        200 mGTATLISVTVLLIASLF-IRHAWCRYLCPYGALMGVVSLl----sPFKIRRN 247 Escherichia coli K-12
WP_015752067   53 DWPPGLLQVGVLVGVTLFl-GRIFCSHVCPLGTTLALVAWl----tRAKRGKR 100 Desulfohalobium retbaense
WP_012375464   54 TGAAFATALALLLALTLA-FGRVYCSVICPLGILQDLIARardalrRKRLRLP 105 Opitutus terrae
WP_015904156   54 GGISGIIVLSFLVLVSLA-FGRIYCAVICPLGIFQDLVRf-----lARRSGRK 100 Desulforapulum autotrophicum
Q60BN6         76 VALIGVVAFFVIITFTFF-FGRIWCSFICPVGGFSELVSRm----lGDRWKIE 123 Methylococcus capsulatus
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