pfam12792: CSS-motif (This model is not part of the current CDD release)
CSS motif domain associated with EAL
This domain, with its characteristic highly conserved CSS sequence motif, is found N-terminal to the EAL (pfam00563) domain in many cyclic diguanylate phosphodiesterases, such as PdeB/C/D/G/N from E. coli K-12. It has two highly conserved cysteine residues with potential disulfide bond formation, which might control the enzymatic activity of the cytoplasmic C-terminal EAL domain.
Jiyao W et al.(2023). "The conserved domain database in 2023.",