2I51


Conserved Protein Domain Family
Pyridox_oxase_2
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pfam12766: Pyridox_oxase_2 
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Pyridoxamine 5'-phosphate oxidase
Pyridoxamine 5'-phosphate oxidase catalyzes the oxidation of pyridoxamine-5-P (PMP) and pyridoxine-5-P (PNP) to pyridoxal-5-P (PLP), the terminal step in the de novo biosynthesis of PLP in Escherichia coli and part of the salvage pathway of this coenzyme in both E. coli and mammalian cells. This region is the flavoprotein FMN-binding domain.
Links
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Statistics
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PSSM-Id: 403846
View PSSM: pfam12766
Aligned: 48 rows
Threshold Bit Score: 89.2231
Threshold Setting Gi: 123753412
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2I51_B         4 LAPWRGAIAHALHRnr---slVYARYLQLATVQ-P-NGR----PANRTLVFRGFLED----------------------- 51  Nostoc punctifo...
Q2S2N5        14 DHVWDA-LETAAEDp-----gHPYRQLTFGTVH---EET----PDLRTVVLRTADA------------------------ 56  Salinibacter ru...
WP_015906183  17 SSSWKS-LHKGVRNf-----rHPFYRPALATMD---GNK----PDVRTVILRGFSD------------------------ 59  Desulfobacteriu...
CAK28407      21 LPPWRPLIRSAQQReg---rsPAARWLQLATVA-L-DGT----PRVRTLVFRGWGG------------------------ 67  Synechococcus s...
XP_002291276  36 SMNWKQRIDISIARsr---kiRASNYVQISTVD-YeTME----PRCRTVVFRGFMKGvpsdvnetlakttdnavghtsng 107 Thalassiosira p...
EEC47289      89 NRSWRSLLEVSSNKsr---ktRGSNYVQLATFD-PeANQ----PKCRTVVFRGFQKLppdhky------------aseld 148 Phaeodactylum t...
XP_011389335 485 QPEWKQILADGIGDnik--neKSILYYAFSTVEqPsSVHdaakPHVRYVVHRGFVNEkrdgdaegg------vashnpaf 556 Ustilago maydis...
EED85206       4 TPRWRTALTKALSLpd----nKGQNVYQLATIDpNdS------PRARTVVHRDIIQPsd--------------------c 53  Postia placenta...
XP_001874182   3 VPRWKIAIETAIAe------yKNQTVFQLATLDpTlPT-----PHVRSHVFRSFLSSef--------------------k 51  Laccaria bicolo...
O94322         2 SLAWKNELLKLLKEnvdssgvIHPEYFQLATLPtGnEIY----PRNRTVAIRGFVGTgwhkpr-------------pddv 64  Schizosaccharom...

2I51_B        52 -TNQ-LRFITDTRSAKADQIQ-----------QQPWA--EICWYFPNTREQFRXAGDLTLIS 98  Nostoc punctiforme PCC 73102
Q2S2N5        57 -GARaLQFHSDRRSRKVAALRe-----------NDRI--AWHAWDTESLEQIRLYGTATVHV 104 Salinibacter ruber DSM 13855
WP_015906183  60 -KDRtLICHCDARSPKVSQIQg-----------NPDV--SWLFYHPDKWLQLRLSGTARVHT 107 Desulfobacterium autotrophicum
CAK28407      68 -PDQ-LDLLTDSRSAKALELE-----------RQPAI--EICWLMPKAKQQFRLRGVWQ--P 112 Synechococcus sp. RCC307
XP_002291276 108 yQDCvMKMITDRRSNKVKELQlfqsvvecktaSASTA--EMVWWFPKSSEQYRIRGRLQFIG 167 Thalassiosira pseudonana CCMP1335
EEC47289     149 gKSCvMKMITDIRSHKVKQVEa---------sEDSAA--EMVWWFSKTSEQYRVQGKLLFVG 199 Phaeodactylum tricornutum CCAP 10...
XP_011389335 557 gSSPcLMTTTDVRTPKVQQLTsqsslrahghdGSRCGecEISWWIESTQMQFRISGTVHVLP 618 Ustilago maydis 521
EED85206      54 pHLPvIITTTDVRTPKVWQLL-----------AYGRT--EICWWMAGSQDQFRIFGPVRVVR 102 Postia placenta Mad-698-R
XP_001874182  52 pNLPlLISSTDIRTPKVTQLA-----------AHPDA--ELAWWIEGVQQQFRISGKVHVVP 100 Laccaria bicolor S238N-H82
O94322        65 lATDlLVFSTDIASHKAAEIAeqqkntfpsgpIPNAF--EMCGWLPKTMQQIRISGQIWLYT 124 Schizosaccharomyces pombe 972h-
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