Conserved Protein Domain Family
Blt1

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pfam12754: Blt1 
Blt1 N-terminal domain
During size-dependent cell cycle transitions controlled by the ubiquitous cyclin-dependent kinase Cdk1, Blt1 has been shown to co-localize with Cdr2 in the medial interphase nodes, as well as with Mid1 which was previously shown to localize to similar interphase structures. Physical interactions between Blt1-Mid1, Blt1-Cdr2 and Cdr2-Mid1 were detected, indicating that medial cortical nodes are formed by the ordered, Cdr2-dependent assembly of multiple interacting proteins during interphase. This domain show similarity to ubiquitin family proteins.
Statistics
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PSSM-Id: 372291
View PSSM: pfam12754
Aligned: 14 rows
Threshold Bit Score: 160.651
Threshold Setting Gi: 121924225
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q5AUF8         6 FTKSFISALDSRPIKLRADYVHDQGNTP-RVP----YTLPRLQP-PRP--SMPKKttaSKTTNPGSSKSITVTLRSARNP 77  Aspergillus nid...
XP_002151077   6 FTRSFLQSVDTKPIRLPYDYVADPVTTRlPVP----YTLPRLQP-PHS--PMAKKi--KTAAAPGSAKSVTVQLKSARNP 76  Talaromyces mar...
XP_001931557   6 FCKSFLSALDARPAKLSSDHIADARQYPaQGA----YTLPRLQHpPHPqrPNPKTs-tDNGSTSTSSQTISITLKPMKPS 80  Pyrenophora tri...
Q0TVJ1         6 FCKSFLTALDARPAKLSSDHIADARQYPaQGA----YILPRLPHpPHPtrPLP-----KNAASSSSSSSLTVSLKPMKPT 76  Parastagonospor...
EDN10768       6 FTKSFLLSLDSQSVKLPSDHVFDPSSFEtPHP----YTLTRLSD-RHP--PMPRKi--KQPTIPGSSKSIRIHLKSARNP 76  Histoplasma cap...
EEQ84558       6 FTKSFLAALDTRPVKLPGDYVFDPSSFSaPHP----YTLPRLSD-FHP--PMPKKr--KQTATPGSSKSITIHLKSARNP 76  Blastomyces der...
XP_002568449   6 FTKSFLSTLDSRPIKLRADHVFDPEQIGlRVP----YTLPRLSA-PHP--PMPKKv--KSTQAPGSSKSITVRVKSARNP 76  Penicillium rub...
XP_001276368   6 FVKSFLAALDSRPVKIRADYVFDPEQVGlRVP----YTLPRLQS-PHP--EMPKKv--HKTQAPGSSKSITVHLKSARNP 76  Aspergillus cla...
CAK42768       6 FIKSFLSSLDSRPIKLRADYVLDEERVGpRVPeneqYLLPRLSA-PHP--EMPKKv--QRTQAPGSSKSITVHLKSARNP 80  Aspergillus niger
Q0C940         6 FIKSYLASLDSRPVKLPADYVFDPERVGlRVP----YLLPRLQP-PRP--EMPKKv--KPTMAPGSSKSITVRLKSARNP 76  Aspergillus ter...
Q5AUF8        78 LLEITLSNVPLATTTVSDLKDAVRERvlentt-eadnkvPLEKIKILFKKKPVtgTG-KTVADVVSDagEEELLAGGKEV 155 Aspergillus nid...
XP_002151077  77 VLEVSLDNVPLTTTTIHDLREAVRQRtvaad---gtqspAADKIKILYKKKPVggSAeRTLAEILGDs-EPEVLSGGKTV 152 Talaromyces mar...
XP_001931557  81 TPTIPLSSIDPAKTSVYDIKQQFATQas----------lSAAKIKILYKKKPV--TDsKTLLEVIGS-------DAGSEV 141 Pyrenophora tri...
Q0TVJ1        77 HPTIPLTDISTSKTSVFDLKSHYAAQss----------iPASKIKILYKKKPVadS--KTVSEVIGQ-------DAAGEV 137 Parastagonospor...
EDN10768      77 ALHITLDNCSIPSTSVGELKEVVQERvqvg-----narvPLDRIKILWKRKPV--QG-ETIAEILEG--DSTVISDGSEI 146 Histoplasma cap...
EEQ84558      77 TLHVTLDNCAISSTTVKELRETVQERvqtadsekkpsrvPLDKIKILWKKKPV--QG-QTIADILGS--DSTALSGGKEI 151 Blastomyces der...
XP_002568449  77 ALEFVISNAPLSTTSVQDIRDAVQVRvtdvq----ggqvPLDKIKILYKRKPVtgTG-KTLAEVLAD--DPAIMAGGKEV 149 Penicillium rub...
XP_001276368  77 ALEFSLPNTALSTTSVQDLKDAVRERvtdaq----gnkvPLDKIKVLYKRKPV--AG-KTVAEVLAD--EPGMLAGGKEV 147 Aspergillus cla...
CAK42768      81 AFEFSLPNAPITTTSVQDLKDAVQERvvdaq----dgkvSVEKIKILYKRKPV--TG-KTIAELLAD--EPEMLAGGKEV 151 Aspergillus niger
Q0C940        77 ALEFTISNAPLATTSVQDLKDAVQARvvdaq----dgavPVDKIKILYKRKPV--AG-KTIAEILSD--EPEMLSGGKEV 147 Aspergillus ter...
Q5AUF8       156 EFGVMIIGG 164 Aspergillus nidulans
XP_002151077 153 EFGIMIMGG 161 Talaromyces marneffei ATCC 18224
XP_001931557 142 EFGVMVMAG 150 Pyrenophora tritici-repentis Pt-1C-BFP
Q0TVJ1       138 EFGVMIMGG 146 Parastagonospora nodorum SN15
EDN10768     147 ELGVMILGG 155 Histoplasma capsulatum NAm1
EEQ84558     152 ELGVMILGG 160 Blastomyces dermatitidis ER-3
XP_002568449 150 EIGVMIIGG 158 Penicillium rubens Wisconsin 54-1255
XP_001276368 148 EFGVMIMGG 156 Aspergillus clavatus NRRL 1
CAK42768     152 EFGVMIMGG 160 Aspergillus niger
Q0C940       148 EFGVMIMGG 156 Aspergillus terreus NIH2624
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