Conserved Protein Domain Family
TraG-D_C
?
pfam12696: TraG-D_C 
TraM recognition site of TraD and TraG
This family includes both TraG and TraD as well as VirD4 proteins. TraG is essential for DNA transfer in bacterial conjugation. These proteins are thought to mediate interactions between the DNA-processing (Dtr) and the mating pair formation (Mpf) systems. This domain interacts with the relaxosome component TraM via the latter's tetramerisation domain. TraD is a hexameric ring ATPase that forms the cytoplasmic face of the conjugative pore.
Links
?
Statistics
?
PSSM-Id: 492829
Aligned: 71 rows
Threshold Bit Score: 91.5678
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
WP_012029890            362 PVLFALDEFLQLGPF-PEFRDAIRTHAGAGVRLWFFLQDVASLEEHYP--RNSWRPFL-NTSIKQFFGi-dDPFTAELVG 436 Brad...
noaausda:RSal33209_1115  66 PLVAVLDEAANICRI-PELPDKYSHYGSRGIMPITILQSYEQGEEAWG--RAGMAKLFsAANLTTVGGsitSTDFLKRVS 142
Q82EV4                  411 PLVGVLDEAANVCRW-RTLPDLYSHYGSRGIILMTILQSWAQGIEVWG--ERGMEKLWsAANVRVYGGgvsDTRFLGDLS 487 Stre...
A0AW99                  412 PALFALDELANVVRW-AGLPDQFSHYGSKGLIVMGILQSWSQGVELWG--EANMRKIWsAANVKVYGGgvaEEGFLRALS 488 Arth...
Q9X8A2                  251 PALCVLDEAANVCRI-SDLPDLYSHLGSRGVIPMTILQSYRQGQRCWG--EAGMDALYsAATIKIIGSgidDADFADRLS 327 Stre...
Q8CJL7                  398 PMLAILDEAANVCKI-SDLPDLYSHLGSRGIIPITILQSYRQGQKVWG--DAGMDAMWsASTVKVIGSgidDPDFADKLS 474 Stre...
Q2JAG4                  417 PLALVLDEAANICKI-ADLPDLYSHLGSRGIVPLTILQSYRQGVRVWG--EAGMDALWsAATIKIIGAgidDPRLAEDLS 493 Fran...
WP_013156507            432 PLVAVLDEAANICKI-ADLPDMYSHLGSRGIVPVTILQSYRQGVRVWT--ENGMEAMWsAATVKVFGAgldDHKIVDALS 508 Noca...
Q11ZG7                  481 RVHLLIDEGSNAICApL-IEI-CNKGRGAGIHVYLAFQAFSDIVTKMGgdVNAAKRFMaNMNNLIVGAt-qDTDTLDLIS 557 Pola...
Q7WWX6                  470 EIVLVVDEAAEAINEqL-LQL-LNKGRGAGFKAFVAYQTRSDFTAKLGn-VAKMQQVLgNLNNQIVLRl-eDIDTAQWFS 545 Cupr...

WP_012029890            437 KYLGTTTVAYRSTNAGNNTSAgrgsy-fendGNTSYSSgESVQFVGRPLLTPDEVMALL 494 Bradyrhizobium sp. ORS 278
noaausda:RSal33209_1115 143 DLIGTYQYN-ERTVSYNSGGQ----------GR-PGGTsIGSQRHTENILEVSDLAALP 189
Q82EV4                  488 ELAGEFELR-DYQTSRSSEFG----------GW-SGNRtVSESVRRERVLQVSDLGSMP 534 Streptomyces avermitilis
A0AW99                  489 DLIGDYSYTNVSISSGKTGSs------------------RSRQEGKERIFDVSNLAELD 529 Arthrobacter sp. FB24
Q9X8A2                  328 RQVGDHDVQ-TTSVSTSEG----------------GKStSVSMR-TERILPPDAIRALP 368 Streptomyces coelicolor
Q8CJL7                  475 RLIGDHDVE-TTSTSHSES----------------GKStSVSMR-QERILPADAIRALP 515 Streptomyces coelicolor
Q2JAG4                  494 RLVGDHDVD-TTSVTRSAQ----------------GASsTISSR-RQRILEAADIRAIP 534 Frankia casuarinae
WP_013156507            509 KLIGQHDIS-TTSFSYGEG----------------KGNhSVQLR-RQEIMQGSDIRRID 549 Nocardiopsis
Q11ZG7                  558 DKFGEVDV-VSANRSQGSGQKtedvgleysaTKSISFS-----EKNRVMIPRSVLMSMP 610 Polaromonas sp. JS666
Q7WWX6                  546 EKAGTTAI-RNLVVSSSTSTGteahigefsgSVSRSAQ-----LEKVPLIPHDLVMQLP 598 Cupriavidus necator
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap