Conserved Protein Domain Family
zf-rbx1
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pfam12678: zf-rbx1 
RING-H2 zinc finger domain
There are 8 cysteine/ histidine residues which are proposed to be the conserved residues involved in zinc binding. The protein, of which this domain is the conserved region, participates in diverse functions relevant to chromosome metabolism and cell cycle control.
Links
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Statistics
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PSSM-Id: 492814
Aligned: 63 rows
Threshold Bit Score: 59.6457
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q4N1R0        28 DNCAICRNHIM--DHCLDCQAKHNKEsqditeqpgCTISWGACGHAFHLHCISTWLKTRRVCPLDN 91  Theileria parva
A0CXI2        25 DRCAIDKQSLF--GQCLECEANQVQDe--------CKIVQGLCNHGFHKHCIDRWLKQSNTCPLCN 80  Paramecium tetraurelia
XP_001299480  37 DTCAICKLSLV--DKCVQCQANDADDsv------pCPPEFGVCGHGFHKHCIDKWVKTNPTCPLCT 94 
XP_001830470 319 RTCIICREEMVfqENQPQATPNDREGpn------mTPKKL-PCGHIFHFYCLRSWLERQQSCPTCR 377
XP_001744458  31 DSCAICLDPLT--RTATQDQRP-------------VRLNI--CRHVFHQACIADWQRQSDACPLCR 79 
EDQ31302     185 IECLICK-----------CEFEKDE----------CMIIL-QCKHKFHDDCIKTWFKFNNACPLCK 228
Q9SVW0       142 YDSQGCLIPIE--EECIICLEELASSgse----rrIMKLL--CSHSFHKDCILPWLRCKRSCPTCR 199 thale cress
XP_001709381  21 AACAVCKIPCH--ELCPTCASTDST----------CSLVKSKCGHVFHTECIHTWLTSNVICPLCA 74 
NP_610691     43 DICAICRVQVM--DSCLRCQADNKRDvmg---rqdCVVVWGECNHSFHHCCMSLWVKQNNRCPLCQ 103 fruit fly
XP_002115565  38 DTCAICKLLLV--DACMKCQNEIKTEd--------CVVVWGECNHSFHRCCIASWLNKSNRCPLCQ 93  Trichoplax adhaerens
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