Conserved Protein Domain Family
TFIIIC_delta

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pfam12657: TFIIIC_delta 
Transcription factor IIIC subunit delta N-term
In humans there are six subunits of transcription factor IIIC, and this one is the 90 kDa subunit; whereas in fungi the complex resolves into nine different subunits and this is No. 9 in yeasts. The whole subunit is involved in RNA polymerase III-mediated transcription. It is possible that this N-terminal domain interacts with TFIIIC subunit 8.
Statistics
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PSSM-Id: 403756
View PSSM: pfam12657
Aligned: 44 rows
Threshold Bit Score: 75.9389
Threshold Setting Gi: 699033238
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EHS64598       74 SSPSCLEWSNDGQAFAVTKANIYLLTPILGYlvspedrhthtqaqptengshsqdapsTPSRSNPSGIQESIAdstTKSA 153  Puccinia gram...
XP_013955562   19 PSPHALAWSCDAELAVATQECIYIFLPDYLA------------------------------------------------- 49   Trichoderma v...
XP_001120537   16 iSKFAVQWSMDNNISILTEKGIHIFELIPSPis-----------------------psSTIKFSRSFIYTPSTfptEIIS 72   honey bee
XP_012059392   16 VNPFAIQWSPDNHISIITEKGVHVLELQPSPms-----------------------pnPFFKFSRSFIYHSDTlpaYAFK 72   Atta cephalotes
EFN83604       16 TIPFAVQWSPDNQISLITEGGVH--ELQPSPms-----------------------pnPIVKFTRSFVNATDIlpaCAFE 70   Jerdon's jump...
EFN61867       16 TIPFATQWSPDNQISIITDKGVHVFELQPSPms-----------------------pnSTIKFARSFIYPPENlpaCSFA 72   Florida carpe...
Q6C759         72 ATGGALAWSDDGDLSIAAGSDAVVLNVNGPItsr---------------------------------------------- 105  Yarrowia lipo...
EDK40866       14 SRCDPAQWSSNSQLAINSGSQITLLDPQVPL------------------------------------------------- 44   Meyerozyma gu...
XP_004201730   15 STCDPVQLSENQQLAVNNGYQLTLLDPKLPL------------------------------------------------- 45   Pichia farino...
CAR65347       15 giTDPLQWSENSQLAVNNGSQLTILDPKLPL------------------------------------------------- 45   Debaryomyces ...
EHS64598      154 ggqpkipffttiieINKQLGVNWSTHSNDISTITPPNDD----------------------------------------- 192  Puccinia gram...
XP_013955562   50 ---------------GHDADADERDASQYQFALSLQPSAvinpstringqlcaqvgvklpap--rtgeegsfrgvgngtv 112  Trichoderma v...
XP_001120537   73 ---------------NRIESKIWNMHREELYSFIIEESMtpklsn----------------------------------- 102  honey bee
XP_012059392   73 ---------------SEVDSSIWDMIREEIYSLLMDDVItpkldg----------------------------------- 102  Atta cephalotes
EFN83604       71 ---------------NEIESMVWKLERKEVYSLLMEEAItpklen----------------------------------- 100  Jerdon's jump...
EFN61867       73 ---------------NKIDSLIWNLDRENIYSILMEETItpiidg----------------------------------- 102  Florida carpe...
Q6C759        106 -----------ddeIDSVRDRNWAQFPETNFTINKSDTMdaipvtaggsts------------------------ipgnq 150  Yarrowia lipo...
EDK40866       45 -------------------------IHQSVYAIPDQETQnksldpkglfhistpihpdilqewpiyrpnsfllddgtepf 99   Meyerozyma gu...
XP_004201730   46 -----------------------IHQSTVNSSLGQDNKGtsileskrifdisgildveareklslgnldkilietldeef 102  Pichia farino...
CAR65347       46 -----------------------IHQSITSSTYGDGSSSftmldpkklfdissildsesidglnlrnldniiiesanekf 102  Debaryomyces ...
EHS64598      193 -------RFWRAATWSPSGLSALGSCLLAGLSTTCDV----------FVYSPCq-NYQAGLWAikETL------------ 242  Puccinia gram...
XP_013955562  113 tgsgaalGQVIRVEWSPNGLGCNSRPVLMALTTTGNLitfgeqadsqSSATSSmrTRTFKNW---RVLwglgaklpipds 189  Trichoderma v...
XP_001120537  103 --vkemvPKIIDLAWSPKDLIHPSKCLIAILTSAGAV----------IIA-----CKICRDWY--PVY------------ 151  honey bee
XP_012059392  103 --vidkfPKIIKVSWSPKNLISPSQCILAILNSAGAV----------ELL-----HKVSNNWY--SIC------------ 151  Atta cephalotes
EFN83604      101 --vndtvLRIIKVEWSPKNLIYPSQCILAILTAAGAI----------ELL-----HKVSNEWY--SIC------------ 149  Jerdon's jump...
EFN61867      103 --vndmnHRIVNIMWSPKNLISPSQCVLAILTTAGTV----------ELL-----HKVFNVWY--SIC------------ 151  Florida carpe...
Q6C759        151 iqygsgdRHVADIAWSPTGLGKMHGCLIGLLNTTHEL----------FIYDHRg-QVEKHSWT--LCH------------ 205  Yarrowia lipo...
EDK40866      100 aiggigePIITGHMWSPIR-SETRDCMLGILINTGEL----------FVLERA--TTTKESYC----------------- 149  Meyerozyma gu...
XP_004201730  103 sfgrinePIIVNHAWSPVN-PTSRDCLLGVLYNTSEL----------LLLERQ--GTNTNDYV--VKY------------ 155  Pichia farino...
CAR65347      103 sfgritePLITSHYWSPLN-PTSKDCYLGVLFNTSEL----------LIFQRS--NFRPSNYA--VKI------------ 155  Debaryomyces ...
EHS64598      243 -------NLSEELLTIFYDfypsiighqedp----------tksidvspetaW----DISEEGEEKRSRFTAGVLRTQAT 301  Puccinia gram...
XP_013955562  190 kskdgfrTMNE------------------------------------------------------------------RIV 203  Trichoderma v...
XP_001120537  152 -------DLSSLRYSIIEQeine-------------------------eleeN-------KNNSASFETFKIYMKALQAS 192  honey bee
XP_012059392  152 -------DIFSLRLKIIEDeiktgl----------------------nksnfH----------ENQSARIVESIKKLQAC 192  Atta cephalotes
EFN83604      150 -------DISALRLNIVQKtikssl----------------------nkcvnS-------PNNVNKYVRITDSMRMLQAC 193  Jerdon's jump...
EFN61867      152 -------DISSLRLKNMKDniis-------------------------nldkC-------KKSKDKYTVIVENMRQLQAC 192  Florida carpe...
Q6C759        206 -------NVADVLYKRVKKetgetngedhptvveeptngdssmidhgedtpkGsragTPSVPGITEQEYTREQYYSFQIH 278  Yarrowia lipo...
EDK40866      150 --------IKHCFFDVLCWq-------------------------------nG----IASNTSADDTKIPVQLYQALRVR 186  Meyerozyma gu...
XP_004201730  156 -------NVFDELLKNLG----------------------------------I----SPDVFTNGEYTLSKMQYMSLKVE 190  Pichia farino...
CAR65347      156 -------NVFHELLSKLH----------------------------------L----TDESFSNGEISMNYEQYLSLKVQ 190  Debaryomyces ...
EHS64598      302 CIAWS 306  Puccinia graminis f. sp. tritici CRL 75-36-700-3
XP_013955562  204 SFSWs 208  Trichoderma virens Gv29-8
XP_001120537  193 CFTWS 197  honey bee
XP_012059392  193 SMTWS 197  Atta cephalotes
EFN83604      194 SMAWS 198  Jerdon's jumping ant
EFN61867      193 AMTWS 197  Florida carpenter ant
Q6C759        279 SFAWS 283  Yarrowia lipolytica
EDK40866      187 SFAfg 191  Meyerozyma guilliermondii ATCC 6260
XP_004201730  191 SFCFn 195  Pichia farinosa CBS 7064
CAR65347      191 CFRfn 195  Debaryomyces hansenii CBS767
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