Conserved Protein Domain Family
DUF3785
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pfam12653: DUF3785 
Protein of unknown function (DUF3785)
This family of proteins is functionally uncharacterised.This family of proteins is found in bacteria. Proteins in this family are approximately 140 amino acids in length. These proteins share two CXXC motifs suggesting these are zinc binding proteins. This protein is found in clostridia in an operon with three signalling proteins, suggesting this protein may be a DNA-binding transcription regulator downstream of an as yet unknown signalling pathway.
Links
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Statistics
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PSSM-Id: 463657
Aligned: 5 rows
Threshold Bit Score: 185.394
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q181X2         4 YKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILNEAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYI 83  Clostridioides ...
1_pfamImport   1 LKFVYDEKEYVLEKDKNVCFLNDEEKPVEGISLDDILNMIDNLEEIDFDTQYYKEACVECLDGVKEKQKFFAFLEYHFYI 80 
Q8XK35         2 FSFTFDEKEYTLSEDKLLYFFNED---VEGFDIDKLFEILNSSEGVSFGKAYYDGPCEECKFGLEEKKKSFPFLEFNMFI 78  Clostridium per...
WP_015395601   3 YKFAYDNKDYLLTNENCEGLFFEDDNEIVGLSLDLILNALNEGEDVAFSNEYYSGKC-SC-NTQDEVNKSYRYLEYHFYI 80  Clostridium sac...
WP_022750588   3 YTFIHENKEYVLSNDNCEGLFFEDENEITGLSFDIILEALNNSNDVNFSNEYYVGKC-QC-GEQEKINKSYRYLEYHFYI 80  Clostridium sac...

Q181X2        84 FSKDGEYVISNISVDYKGLSFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV 139 Clostridioides difficile 630
1_pfamImport  81 YTKDQKFIISDIQKEYEGQSFNKLLRANKVDDSYIVSLIICKNCGDTLIQIENCVV 136
Q8XK35        79 YAKNGKFVISNIEKAYEGLTYNKLLRDKKVDKSYLVNINVCKNCGNFAVEVEELEV 134 Clostridium perfringens
WP_015395601  81 YTKNKEYVINTIENEYKATSFNKLFNAGKIDDSYIVIVTACPNCGVYSISVEQCTV 136 Clostridium saccharoperbutylacetonicum
WP_022750588  81 YTKNNTYVINTISKEYENTSFNKLFNLGKVDDSYIINVTVCPICGLYAIEVSQCTV 136 Clostridium saccharobutylicum
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