Conserved Protein Domain Family
TSCPD
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pfam12637: TSCPD (This model is not part of the current CDD release)
TSCPD domain
This family of proteins is found in bacteria, archaea and viruses. The domain is found in isolation in many proteins where it has a conserved C-terminal motif TSCPD after which the domain is named. Most copies of the domain possess 4 conserved cysteines that may be part of an Iron-sulfur cluster. This domain is found at the C-terminus of some ribonucleoside-diphosphate reductase enzymes.
Links
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Statistics
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PSSM-Id: 520374
Aligned: 126 rows
Threshold Bit Score: 80.9829
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_012201723    3 FKTNGVCASEINFEVEekDGkkIVTDVKFTGGCNGNLQGISKLVKGMPVDEVIEKLQGLQCGYKSTSCPDQLAEALKQ 80  Lachnoclostridiu...
WP_022290405    3 YQTKGTCAKEIKLELD--HG--IIRSVEFVLGCPGFTQALSRLLVGMRAEDAIAQLKGIQCLEKGTSCPDQLAIALSQ 76  environmental sa...
Q728G4          4 YVPKGVCAKQISFSIE--DG--LLHDVRFAGGCPGNLEGISRLLEGMPVEAVIEKFSGITCGNKPTSCPDQLAKILAQ 77  Desulfovibrio vu...
27_pfamImport   1 YKTKGTCSTQIEVELD---Gn-IVKNVKFTGGCQGNLQAIPRLVEGMTVEEVERRISGIHCGMKNTSCGDQLAKALRE 74 
WP_022514757    5 YQTKGTCSSKIEVELD---Gn-VVKHVKFTGGCPGNLLAIPKLVEGLTVEQVEEKLTGIHCGMKQTSCGDQLAHACRE 78  Roseburia yibonii
25_pfamImport   1 YKTKGTCSTMIEVELD---Gh-IVKDVKFTGGCNGNLKAIPKLVQGLTVEQVEEKLSGISCSGRPTSCGDQLAKACRA 74 
CCZ91619        7 YKTKGTCARVIDLDID---Gd-RISNVKFTGGCDGNLKAIPALVEGMTVDQIRQRVAGIKCGFKDTSCADQLAKAVLE 80 
32_pfamImport   1 YKTRGTCSSQIDFDIN---Gd-VITNVAFTGGCNGNTQGVASLVDGLTVTQIEDRLKGIQCGMRGTSCVDQLSHAVRE 74 
43_pfamImport   1 YYTKGTCSKQIDLEIN---Gd-VITNVKFYGGCDGNLKAIPALVDGLTVDEISNKLSGIQCGFKGTSCGDQLAHAVRE 74 
24_pfamImport   1 YTTKGTCSSEIEFDLD---Gd-IVHNVQFVGGCNGNLKAISSLVDGLTVEQVVDKVKGITCGFKSTSCSDQLATALLE 74
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