Conserved Protein Domain Family
PHF20_AT-hook
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pfam12618: PHF20_AT-hook (This model is not part of the current CDD release)
PHD finger protein 20, AT-hook
PHD finger protein 20 (PHF20) is a Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. It consists of tandem Tudor domains at the N-terminal, an AT hook, a C2H2-type zinc finger, and a plant homeodomain (PHD) finger. This entry represents the AT-hook domain, a putative DNA-binding domain.
Links
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Statistics
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PSSM-Id: 520363
Aligned: 6 rows
Threshold Bit Score: 76.8333
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
NP_001164807  176 VKKDKEDKALKTEKrsrqpd-qegklICSEKGKASERSLPENEKEDKENISENDrEYSGDTQLDKKPGSDIGKS---PQE 251 
NP_001101265  176 VKKNQVEKALKTEKrpkppd-kegklTCPEKGRVSEKSLPKNEKEDKENISENErEYSGDAQVDKKPEKDLVKS---PQE 251 
XP_030144728  175 AKKDEDEKTVKTEKrvkqpdkegkfiVISEKGKISEKNISKNGKEDKENISENDmEYSVDTQVEKKPENDKVKS---PQE 251 
3_pfamImport    1 SKKEEQTSTCKS--------------ITEDIQKKHEEAL----SSEKSGINPNN-TYLLDTIKCKQSEASTSKKrkiSQG 61  
XP_021322610  200 GEEEEEEEDSESEK------------------------LADLDSEEEDSKPPAE-----------ELESAIAKRrskRQG 244  zebrafish
XP_056667774  175 akkdkddkTLKAEKrarqpd-kegklVSPDKGKGSEKGLLKNEKEDKENISENDrEYSGETQADKKPENDIVKN---TQE 250  gray short-ta...

NP_001164807  252 NLREPKRKR-----------------GRPPSIAPA-AVDSNSQTLQP 280 
NP_001101265  252 TLKEPKRKR-----------------GRPPSITPT-AVDSNSQTLQP 280 
XP_030144728  252 NVKETKRKR-----------------GRPPVTPPT---EPSSQTLQP 278 
3_pfamImport   62 TSFQAKRARlnkitgl----lafkavGVDGSEKQDdGAETSKASEQE 104 
XP_021322610  245 NQCSIKRSRlgkgagcadtetelkaeTKELPVTPQqKVPSPEPSPAD 291  zebrafish
XP_056667774  251 NLREPKRKR-----------------GRPPSIPQS---EPNSQTLQP 277  gray short-tailed opossum
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