Conserved Protein Domain Family
TBX

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pfam12598: TBX 
T-box transcription factor
This domain family is found in eukaryotes, and is typically between 77 and 89 amino acids in length. The family is found in association with pfam00907. There are two completely conserved residues (S and P) that may be functionally important. T-box genes encode transcription factors involved in morphogenesis and organogenesis of vertebrates and invertebrates
Statistics
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PSSM-Id: 403708
View PSSM: pfam12598
Aligned: 15 rows
Threshold Bit Score: 69.4003
Threshold Setting Gi: 573905234
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
NP_001027524 304 RPYD-DH---QKKDNGSSDESSSE-QTAYKcfAQTSSPtAPAVgtSSLKGVPPSDgESD--EESRDEGGPDtgestKIST 376 tropical clawed...
Q7ZTU9       294 RMYE-DQc-kVDRDGADSDASSSE-PTTGR--DAGHSP-GPVS--SPLRFNRGSR-DDKtcTDSEHEMDHQ-----NDRC 359 zebrafish
XP_007258937 293 HMYDvGQc-kVDRDGGDSDASSGE-PPSGR--ETAHSPlRPAS--SPLTFTRSAR-DDKqcSDSEHETDTQ-----EEHC 360 Mexican tetra
XP_004075985 293 RMYE-DQc-kADREGADSDASSSE-PPAGR--DAVHSPvGGGT--SPLRFSRPSR-DEKtcTDSEQELEHH-----DEH- 358 Japanese medaka
XP_005986878 295 RMYE-EQc-kPDRDGAESDASSSE-PPQGR--DTLHSPlGAEP--SPLRLNRNSR-DEKicADSDQELEKP-----YELS 361 coelacanth
Q3SA48       295 RMYE-EQc-kADRDGAESDASSCD-PAPGR--DSLHSPlSTEP--SPLRLHRSNR-EEKfgADSDQELDRR-----EVRT 361 tropical clawed...
XP_007659073 112 RMYE-EQpckPERDGAESDASSCDpPPPAR--EPPPSP-GTQP--SPLRLHRGRD-DKScvADSEPEPERAgpgeeRAGA 184 platypus
NP_001095854 293 RMYD-DQc-kVDRDGGDSDDSSCE-QTTGR--DSVHSPtGPAT--SPLKFTR-SR-EDKnfNESDNELDQH-----DDGM 358 zebrafish
CAF99197     322 RSYE-EQ---QKKENGASDDSSGE-QAPFKcfGQASSPaVSTVgpPHLKDYCDSDeDSD--DESKDGHIKDgpdssKIS- 393 spotted green p...
XP_007254062 306 RSYE-EQ---QKKENGTSDDSSGE-QASFKcfRQASSPaVSTAgqPNLKDFCDSDeDSD--EDDKDAQLKEgpdssKIST 378 Mexican tetra
NP_001027524 377 TTSEDCRELA 386 tropical clawed frog
Q7ZTU9       360 GGSSSPAPEP 369 zebrafish
XP_007258937 361 GESSSPGPKP 370 Mexican tetra
XP_004075985 359 -GSNSPGTEP 367 Japanese medaka
XP_005986878 362 AGNHSPGVQP 371 coelacanth
Q3SA48       362 ARSHSPVGHR 371 tropical clawed frog
XP_007659073 185 AAGQSPGPEP 194 platypus
NP_001095854 359 IRVSSPEQRP 368 zebrafish
CAF99197     394 TTTEDGKDHE 403 spotted green pufferfish
XP_007254062 379 TTTEDAKEHD 388 Mexican tetra
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