Conserved Protein Domain Family
Acyl-thio_N

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pfam12590: Acyl-thio_N 
Acyl-ATP thioesterase
This domain family is found in bacteria and eukaryotes, and is typically between 120 and 131 amino acids in length. The family is found in association with pfam01643. The plant acyl-acyl carrier protein (ACP) thioesterases (TEs) have roles in fatty acid synthesis.
Statistics
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PSSM-Id: 403703
View PSSM: pfam12590
Aligned: 16 rows
Threshold Bit Score: 165.753
Threshold Setting Gi: 548846855
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9SNP5         1 MAGS--LAASAFFPVPGSSPAASARSSKNTtg---eLPENLSVRGIVAKPNPsPG-----AMQVKAQAQALPKVNG-TKV 69  Japanese rice
KRH56678       1 MVAT--AATSSFFPVTSPSPDSGGA-GSKL------GGGPANLGGLKSKSAS-SG-----GL--KAKAQAPSKING-TTV 62  soybean
ABV54795       1 MVATaaAATSSFFPVPSQSADANFD------------KAPASLGGIKLKSTScSR-----GLQVKANAQAPPKING-SSV 62  castor bean
KRH63043       1 MVAT--AATASFLPVP--LPDAGKGKPKKLggggggGGGSVNLGGLKQKQGL-CG-----GLQVKANAQAPPK------- 63  soybean
XP_006366870   1 mmAT--AATCAFFPAANPPPDSGAKSSGNLgg---sLPGSIDTRGLNVKKPS-FG-----SLQAKANAQAPPKVNG-TKV 68  potato
ERN06084       1 MVATv-AFSSAFLPVGSSLSAQNSSASSN-------GKASMALGG-NSKPVS-YG-----GVQAKANAQAPPKING-TKV 64  Amborella trich...
XP_009388536   6 AVAS------AFFPGPSSSSVVSAKASKAIg----eGPENLGVRGIVAKPMSvSG-----AMEVKAQAQAIPKVNG-TKV 69  wild Malaysian ...
XP_009419293   1 MVAS--V-AAAFFPVPSSSSTVLAQASKSIg----dGPRSLGIQGIVAKPNSsSG-----AMEIKAQAQTLPKING-TKV 67  wild Malaysian ...
XP_002453522   1 MAAS--VASSAFFPVP-------ASAPKNApg---rSKDNLDMGGVAANVGAvRSs----SARARAHA-AVPKVNSgGKA 63  sorghum
Q0DB74         1 MAGS--IAASAFLP---GSPA--AAPPKSVlg---eRPDSLDVRGIAAKPGSsSSaaalrAGKTRTHA-AIPKVNG-GSS 68  Japanese rice
Q9SNP5        70 NLKTTSPDKEDI----IP--YTAP-----KTFYNQLPDWSMLLAAVTTIFLAAEKQWTLLDWKPKKPDMLAD 130 Japanese rice
KRH56678      63 --VTSKESFKHDd--dLP--SPPP-----RTFINQLPDWSMLLAAITTIFLAAEKQWMMLDWKPRRPDMLID 123 soybean
ABV54795      63 GFTTSVETVKNDg--dMPl-PPPP-----RTFINQLPDWSMLLAAITTIFLAAEKQWMMLDWKPRRPDMLID 126 castor bean
KRH63043      64 ----TVEKVENDlsssSSsiSHAP-----RTFINQLPDWSMLLAAITTVFLAAEKQWMMLDWKPRRPDMLID 126 soybean
XP_006366870  69 GV---MDGFKNDd--eVIs-SHHP-----RTFINQLPDWSMLLAAITTIFLAAEKQWMMLDWKPKRPDMLAD 129 potato
ERN06084      65 GL-----GLKEAqdeeVS--SSSPsptqsKTFINQLPDWSLLLTAITTIFLAAEKQWTNLDWKPRRPELVda 129 Amborella trichopoda
XP_009388536  70 GLKTEAQKVEED----SP---SAP-----RTFYNQLPDWSFLFAAITTIFLAAEKQFTLIDWKPRRPDMLAD 129 wild Malaysian banana
XP_009419293  68 DLKTKEHKADEEe---VA---SVP-----RTFYNQLPDWSFLFAAITTIFLAAEKQLTLLDWKPKRPDMLAD 128 wild Malaysian banana
XP_002453522  64 AVTDGEDDASRSs---AP--APAP-----RTFYNQLPDWSVLLAAITTIFLAAERQWTLVDWKPKRPDMLID 125 sorghum
Q0DB74        69 ALADPEHDTMSSs---SS--SAAP-----RTFYNQLPDWSMLLAAITTIFLAAEKQWTLLDWKPKRPDMLTD 130 Japanese rice
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