5FMV


Conserved Protein Domain Family
CD45

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pfam12567: CD45 
Leukocyte receptor CD45
This family of proteins is found in eukaryotes. Proteins in this family are typically between 77 and 1130 amino acids in length. The family is found in association with pfam00041. CD45 plays a critical role in T-cell receptor (TCR)-mediated signaling. CD45 interacts with SKAP55 which is a transcriptional activator of IL-2.
Statistics
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PSSM-Id: 403683
View PSSM: pfam12567
Aligned: 16 rows
Threshold Bit Score: 71.2481
Threshold Setting Gi: 44242018
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5FMV_A         16 VDYLYNKETKLFTAKLNVNENVECGNNT------CTNNEVHNLTECKNA-SVSISHNSCTAPDKTL 74  
XP_023370328  109 VDYNYDSTKKSFTAKLNVNDKVECSGFVn-----CTNNEFHNLQQCTSF-TVNITHHTCAGPPKQL 168  small-eared galago
XP_003130644  192 VNYTYTYNENSKTYSVMFASDVQCDSQD------CAK-MLQNLQECEHR-TVNLSHSSCVPPFKQI 249  pig
XP_013013472  238 VEYKYDSRTKLFTANLLGADSVKCHSPE------CEK-TLQGLHECSHV-TVLIGDGNCSSPIHLQ 295  domestic guinea pig
NP_001255215   49 VNYTYESSNQTFKADLKDVQNAKCGNED------CEN-VLNNLEECSQIkNISVSNDSCA-PATTI 106  house mouse
EGW06747       75 VYYDYNSNKKSFEAKLKGDKNPQCEAAD------CEK--LKNLQECSQS-NFTVSNGSCI-PHKII 130  Chinese hamster
ELW57889      263 VGYEYDYINHTYSATLNATETVECQPE-------CINNTVHGLKECENI-DISISHTSCAFPNKIV 320  Chinese tree shrew
XP_004093212  237 VDYLYNKETKEFMAKLNVNEKVECGNNN------CTNNEVHKLAECKEI-NVSISHNSCTSYKELK 295  northern white-cheeked gibbon
XP_005608102  172 VNYSYNHANQSYDAKLNVTDEVECNSTEpngyisCVNNMFHGLPECKIF-TVRIYHNSCSSYKEFK 236  horse
AAS46951        8 VDYLYNNKTKLFTAKLNVNENVECTNNNhth-niCTNNEVLNLPECKEM-IVFVSHNSCTDRHKEL 71   pig-tailed macaque
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