Conserved Protein Domain Family
TypeIII_RM_meth

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pfam12564: TypeIII_RM_meth 
Type III restriction/modification enzyme methylation subunit
This domain family is found in bacteria, and is approximately 60 amino acids in length. The family is found in association with pfam01555. There are two completely conserved residues (F and S) that may be functionally important. This family is a bacterial phage resistance protein. It functions in a type III restriction/modification enzyme complex. It is part of the methylation subunit of the complex. It binds DNA and methylates it.
Statistics
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PSSM-Id: 492722
Aligned: 8 rows
Threshold Bit Score: 60.7844
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_024267432  37 EPMLIKLLLSDKKIKKHFFQDI-EGTFVFDKIKFQKFISNKQFLPDSYTAFKNKVGL 92  Salinispira pacifica
WP_014095940  39 DSNLIKLLLSNEETKKRFFTDI-DGILVFDKVGFGWVINNREFLPDSYTRYKNKIGL 94  Heyndrickxia
WP_012993119  38 NENLLTLLLSNKDVKETFFKNV-QGMLVFDKQKFAWFMESKEFLPDSYTAYTNKIGL 93  Mageeibacillus indolicus
WP_012744579  37 DKGLIKLLLKNKRIKEHFFKDV-DGVLVFDKEKFMKFIDNKEFLPDSYTAFKNKIGL 92  Kosmotoga olearia
WP_002955891  33 NRELLSFLLENAEFRERFFTRV-DSVAVFEKDKFLDFLKLR-MLNKSYTAFSNKIGL 87  Helicobacter cinaedi
P71366        41 DPTIIGLLLGNDDLKRHFFVEV-NGVLVFKLQDF-RFFLDKHSINNSYTKYANRIGL 95  Haemophilus influenzae Rd KW20
Q5M4P5        42 DEALLSKLFEVDFIMQHFVKEV-AGQKLFQIEQLEEAVLYNDYWDTSYTKYENRVGL 97  Streptococcus thermophilus LMG 18311
WP_012108571  36 DKILIDLLI-NSKFKELFFEKLqNDIWIFKQKTFIDYIDDKNFLLDSYTKFSNKIGL 91  Campylobacter hominis
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