Conserved Protein Domain Family
GPHR_N

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pfam12537: GPHR_N 
The Golgi pH Regulator (GPHR) Family N-terminal
GPHR_N is the N-terminal 5TM region of the Golgi pH regulator proteins in eukaryotes. It plays vital roles in the transport of newly synthesized proteins from the Golgi to the plasma membrane, in the glycosylation of proteins along the exocytic pathway and the structural organisation of the Golgi apparatus.
Statistics
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PSSM-Id: 403659
View PSSM: pfam12537
Aligned: 88 rows
Threshold Bit Score: 34.8141
Threshold Setting Gi: 74832195
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_001526926             227 LMERKINEVSIVGITILAILSGAGSASTPYRVISMdslkkLtnykgansstLQTSSnssegiERDINLAIRNYNNTTLLL 306 Lod...
CAR27960                 178 YTENILTKLSIVGITVMAMLSAVASVSTLYYTYTT-----LrsrikyssadHSQKV-------FDDNSTGTLLWYADDMV 245 Zyg...
CCF58122                 182 YTSNILTRLSIGGVTIMAMLSGIACASTLYYTYLF-----IknrskrkylpISSTA------ADSIQNRKLLLWSNRSRF 250 Kaz...
Q6FNM0                   180 YSKSILTSLSIAGVTVMAILSGIASISTLYYTFSM-----IfkrrsdisgmQSSS--------LISRNRRLNLWTTQRQL 246 [Ca...
CCD23850                 141 YTRNILTKLSIAGVTLMAILSGIATVTTTYYTFLYvwrkyVirnknkstlvPSV---------DDRINQRFVIWATDEDI 211 Nau...
XP_004181995             179 YTYNILTKISIAGVSILAILSGIATVSTLYYTFTF-----IwkrgtasklgLSTI--------NRRTNSNSLLWTTDVSV 245 Tet...
CAR23214                 180 YSTNMLTKLSIMGVSVMAFLSGVASVSTPYYVFQL-----Irykr--------------rkpdSSFSERIPVAWMDDVVL 240 Lac...
Q6CQY8                   206 YTYNLLTKASVIGVTVMGILSGLASVSTPYYAYQY-----Frhrnk-------------rdtkYTIHNNVDLLWSSESVI 267 Klu...
Q74Z40                   180 YSSSPLTRLSLVGVTIMGVLSGIASMSTPYYVARF-----LlnwqkdapvvL-----------NHAFSHISMMYFSTAMI 243 Ere...
WGS:AAFB:cds.EHI_196900A  96 SLYGLLEKLAVIGIFISAILSGYSSIQLPMKHLDP-----F----------HKRYS------DEQIKTKYAQLK-----F 149 Ent...
XP_001526926             307 SKREQEL 313 Lodderomyces elongisporus NRRL YB-4239
CAR27960                 246 IKKIEEY 252 Zygosaccharomyces rouxii
CCF58122                 251 HEKLdyy 257 Kazachstania africana CBS 2517
Q6FNM0                   247 QSQIDNY 253 [Candida] glabrata
CCD23850                 212 KEKlkiy 218 Naumovozyma dairenensis CBS 421
XP_004181995             246 MEKIHDY 252 Tetrapisispora blattae CBS 6284
CAR23214                 241 REQKGEC 247 Lachancea thermotolerans CBS 6340
Q6CQY8                   268 RDRIRNY 274 Kluyveromyces lactis
Q74Z40                   244 QERMQEY 250 Eremothecium gossypii
WGS:AAFB:cds.EHI_196900A 150 MEQRGET 156 Entamoeba histolytica HM-1:IMSS
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