Conserved Protein Domain Family
Smoothelin
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pfam12510: Smoothelin (This model is not part of the current CDD release)
Smoothelin cytoskeleton protein
This domain family is found in eukaryotes, and is approximately 50 amino acids in length. The family is found in association with pfam00307. Smoothelin is a cytoskeletal protein specifically expressed in differentiated smooth muscle cells and has been shown to co-localize with smooth muscle alpha actin.
Links
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Statistics
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PSSM-Id: 520308
Aligned: 11 rows
Threshold Bit Score: 43.1749
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_055230204  570 KAPEGRSPLSAEELMTIEDEGVLDKMLDQSTDFEERKLIRAALRELRQRK 619 
XP_012812963  657 AEPENKGKLTAEDLNAIEEEEVLDKMLDKATDFEERKLIRAAMRDLRQRK 706 
4_pfamImport    1 SKTDGKSSLTSEELAAIEDEDVLNKMLDNTSDFEERRMIRSALRDLLKKK 50  
7_pfamImport    1 EEQQAALTALSEQLEAITSVEELTKLLRAAGEYEERKLIRAAIRKLRAEE 50  
NP_001259279 3127 SSSSAPVTRTTCDIEEIWDEQVLKQLLEQASTYEERRKIRARLRELMAER 3176
EDW00113     3189 LRTTSISEDFDIDIEAIFELATLEQLLETVSSYELRRRIRAQIRLIKKNM 3238
NP_001259278  206 DEDS----DLELEIEEIFDLQRLEKLLETVASYEMRRRIRAQMRLIRKNM 251  fruit fly
XP_047297423   46 EPTELGASEMADEALAGLDEGALRKLLEVTADLAERRRIRSAIRELQRQE 95   human
XP_047297423  127 AEQRAALARLAGQLESMNDVEELTALLRSAGEYEERKLIRAAIRRVRAQE 176  human
XP_029693349   15 ESKASAGKLSSEELAAIEDEEVLNKMMDTAADFEDRRLIRAALRDLLKRK 64   torafugu
XP_025011426  637 REVEKKSKLNVEELNRIEDEDVLDKMLDQTTDFEERRLIRNAMRELRQRK 686  chicken
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