This domain is found in Golgi associated RAB2 interactor proteins and it is likely a Rab2B-binding domain. Some members included in this entry, such as GAR1A/B and GAR2, are RAB2B effector proteins required for accurate acrosome formation and normal male fertility. GARI-L4 is a RAB2B effector protein required for the compacted Golgi morphology. GARIL5 is a Rab2B effector protein which promotes cytosolic DNA-induced innate immune responses.