Conserved Protein Domain Family
Malate_DH

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pfam12434: Malate_DH 
Malate dehydrogenase enzyme
This domain family is found in bacteria, and is approximately 30 amino acids in length. The family is found in association with pfam00390, pfam03949, pfam01515. There is a conserved AAL sequence motif. There is a single completely conserved residue R that may be functionally important. Malate dehydrogenase is one of the enzymes involved in the citric acid cycle in mitochondria. It converts malate to oxaloacetate using NAD as a cofactor.
Statistics
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PSSM-Id: 492618
Aligned: 2 rows
Threshold Bit Score: 68.7459
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q0K6Z3   1 MtspqQSPSQDDLKQQQREALRKAALEYHEFP 32  Cupriavidus necator H16
Q121Q8   3 T----PTAATPDNRDEKRAELRRAALEYHEFP 30  Polaromonas sp. JS666
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