Conserved Protein Domain Family
Pax2_C
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pfam12403: Pax2_C (This model is not part of the current CDD release)
Paired-box protein 2 C terminal
This domain family is found in eukaryotes, and is approximately 110 amino acids in length. The family is found in association with pfam00292. This family is the C terminal of the paired-box protein 2 which is a transcription factor involved in embryonic development and organogenesis.
Links
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Statistics
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PSSM-Id: 520248
Aligned: 16 rows
Threshold Bit Score: 109.885
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_005988293 433 SSMA-PFSAFSHHTPVYGQFTGQAIIPGRDMVGSALPGYPPHIPaSGQGSYASSAITGMV-AGSDYTGNAYSSSPYSSYS 510
XP_005460264 353 NHFPnAFNSFSHHAPVYGQFSSQSVISGRDMVSSTLPGYPPHIPsPAQTGYSSSAITGMVaAGADYSGQSYSHSPYTSYS 432
XP_004401984 280 VKSSlSASTNPELGSNVSGTQTYPVVTGRDMASTTLPGYPPHVPpTGQGSYPTSTLAGMV-PGSEFSGNPYSHPQYTAYN 358
3_pfamImport   1 NSLA-NPGAGAELGGSVSGPQSYSLVPGRDLSSTTLPGYPPHVPpTGQGSYSTPSLTGMV-PGRCYASSPAGTQSRAIYN 78 
1_pfamImport   1 SSLA-NP-TPADLGTSVPGAQSYQLVAGRDLASTTLPGYPPHVPpAGQGSYSTPALTGMV-PGSDFSGSPYTHPQYSTYN 77 
XP_015201926 349 ASTP-SYCAYAHRGSSYGQYASQPLIAGREMASTTLPGYPPHVPpTGQGSYPTSTLAGMV-PGSEFSGNPYTHPQYTTYN 426
XP_029705979 173 NSLA-NPGTGAEIGASVTGPQSYSLVPGRDLASTTLPGYPPHVPpTGQGSYSTPSLTGMV-PGGDFSGSPYSHPQYSTYN 250 torafugu
XP_029705978 253 NSLA-NPGTGAEIGASVTGPQSYSLVPGRDLASTTLPGYPPHVPpTGQGSYSTPSLTGMV-PGGDFSGSPYSHPQYSTYN 330 torafugu
XP_056705414 281 SSL--STSANPDLGNNVSGPQTYPVVTGRDMASTTLPGYPPHVPpTGQGSYPTSTLAGMV-PGSEFSGNPYSHPQYTTYN 357 tarantolino
XP_018083072 349 ASTP-TYSSFTHHGPPYGQFGSQPLIAGRDMSSTTLPGYPPHVPpTGQGSYPTSTLAGMV-PGSEFSGNPYSHPQYTTYN 426 African clawed ...

XP_005988293 511 EAWRITNSG----LL-----------------------------GSPYYYSSASRTTAPpa------aAAAYDH 545
XP_005460264 433 EAWRFTNSS----LL-----------------------------GSPYYYSSASRTGPPs--------AAAYDH 465
XP_004401984 359 EAWRFSNPA----LL-----------------------------SSPYYYSAAPRGSAPaa------aAAAYDR 393
3_pfamImport  79 TPQRWASPSgsadLF-----------------------------QQDY---GSLLGTEIgc------sSGLFTS 114
1_pfamImport  78 ESWRFPNPS----LL-----------------------------VFQQDYG-SRLGSEIgc------tSGFFPG 111
XP_015201926 427 EAWRFSNPA----LL-----------------------------MPH-------LEAPPlpllplpttATSY-H 459
XP_029705979 251 ESWRFPNPS----LL-----------------------------VFQQDYG-SLLGTEIgc------sSSLFTS 284 torafugu
XP_029705978 331 ESWRFPNPS----LLvfqqdygsllgteigcssslftsqagqmqGSPYYYSATSRGAGSaa------tATASAY 394 torafugu
XP_056705414 358 EAWRFSNPA----LL-----------------------------SSPYYYSATSRGAAPpt------aAAAYDR 392 tarantolino
XP_018083072 427 EAWRFSNPA----LL-----------------------------SSPYYYSATSRGSAPpt------aATAYDR 461 African clawed frog
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