Conserved Protein Domain Family
Dmrt1

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pfam12374: Dmrt1 
Double-sex mab3 related transcription factor 1
This domain family is found in eukaryotes, and is typically between 61 and 73 amino acids in length. The family is found in association with pfam00751. This family is a transcription factor involved in sex determination. The proteins in this family contain a zinc finger-like DNA-binding motif, DM domain.
Statistics
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PSSM-Id: 403548
View PSSM: pfam12374
Aligned: 19 rows
Threshold Bit Score: 58.9944
Threshold Setting Gi: 82098132
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P85119        86 ELGISHPIPLPiAAELLIKREHGGSsSCLMLE-----SSSTQTTSTSTSGSTTSSEGKMLIQEIPSITSRGHLESTSD 158 tropical clawed frog
XP_006001259 114 ELGISHPIPLPsAAELLVKRESNGNgSCLLVEggvggGGGATPTASNSAGSASATEGRVLVQEIPSISSRGHLESTSD 191 coelacanth
Q5YD53        76 EMGICSPINLS-GSDTLVKNEAVGE--NVFTLs----SGPPSPASSSATASPTNLGSRSMLSLSPAMSSRGHTDCTSD 146 zebrafish
XP_015194169 112 EMGICSLVPFP-NPDVVIKNEASGDrACLFSAr----GKSPPSSTSSRATTPPATGSRSSQQDSPSAASRGYAEGTSD 184 spotted gar
APF31796      58 ELGICSPVPLS-GAGMMVKNEAGAE--CFFSAe----GRNQAAT--STSSSSVVPASRSVTSSRPSAGARAANDGQSD 126 komon-damashi
CAG08193      83 ELGIWSLGPLP-GAGVMVKNEPGAE--CCFTVe----GRSQTST--SGPSSAVATASRTVPSSQPSAGARAHHEGQSD 151 spotted green puf...
Q801F8        81 ELGICSPEASS-GPEVMVKNEAGAD--CLFSMe----GRSGTPA--VPPNPLSAAGSCSASSSSPSAAARVYGEEASD 149 Japanese medaka
NP_001254571  86 ELGICSPVALA-GPDVTVKNEAAAD--CLFSEe----GRSPSPS-----PSLAVTGGRSASSPSPSAGGRALAEGPSD 151 three-spined stic...
AAF79931      85 ELGICSPVSLS-GSEMMVKNEVGAD--CLFSVe----GRSPTPT---SHATSAVTGTRSASSPSPSAAARAHTEGPSD 152 Nile tilapia
XP_003216601  35 ELGISHPIPLPnATEMYVKKEGSANgSCLLLEs----SSPQQSTTAATTVSSASTEGRMLIQDIPSLASRGHLESTSD 108 green anole
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