Conserved Protein Domain Family
HJURP_C

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pfam12347: HJURP_C 
Holliday junction regulator protein family C-terminal repeat
Although this family is conserved in the Holliday junction regulator, HJURP, proteins in higher eukaryotes, alongside an Scm3, pfam10384, family, its exact function is not known. The C-terminal region of Scm3 proteins has been evolving rapidly, and this short repeat at the C-terminal end can be present in up to two copies in the higher eukaryotes.
Statistics
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PSSM-Id: 403531
View PSSM: pfam12347
Aligned: 32 rows
Threshold Bit Score: 53.8941
Threshold Setting Gi: 1604842583
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
EFN62369      62 KKehkgamspESPEPDAI--EYnLTPRTEAKYTKIDEEFQMMMQRHQHNGsrtmgQSNY------TLPVSVPVNSY 129 Florida carpenter ant
Q6S5H1        90 KKenk---qlSSPEETDK--QFvLTPRTEAKYNKINEEFDQMMKKNFIPQ-----QSNAggdypsQMPVAIPVQHS 155 starlet sea anemone
XP_028440015  87 klrnkghndcASPDPEDC---FgHSPLMDDHFGKLNEESDLMYKRCGPTAl---pQQNF------SMHVAVPVSNP 150 yellow perch
AAI55417      87 tlrkkglngcDSPDPD-AddSVgHSPESEDKYRKINEDIDLMISRQRLCAv---pPPNF------EMPVSIPVSNP 152 tropical clawed frog
XP_003967108  90 KKehr---gcDSPDPD-A--SYvLTPHTEEKYKKINEEFDNMMRNHKIPSal--pQQNF------SMHVAVPVSNP 151 torafugu
XP_007246204  62 KKehr---gcESPDPDTS--SYiLTPHTEEKYQKINEEFDNMMRNHKIPAvl--sQQSF------TLPVAVPVDDP 124 Mexican tetra
XP_013013229 535 KA--------ASPSQAISapGTdPLSRPKSSYAEIKARFDQLHQRILQMSp-----qQA------KVPSHVGMCGN 591 domestic guinea pig
EGW13599     524 KA--------VSPSTANSvpWTsPWGHGRNRYDEIKEEFDKLYQKYCLMSpp----qQV------KMTSCVTVSSK 581 Chinese hamster
XP_006529784 451 KA--------VWPSTAISapSIgSPGCGKDNYDELKKEFNRLYQKYCL-Sp-----qRA------KVTSCGRVSPM 506 house mouse
NP_001178742 533 KA--------AWPSTAISapDFpDCG---GHYDELKKEFNRLYQKYCLVSp-----rHA------KVTLCGRLSPV 586 Norway rat
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