Conserved Protein Domain Family
BCLP
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pfam12304: BCLP (This model is not part of the current CDD release)
Beta-casein like protein
This protein is found in eukaryotes. Proteins in this family are typically between 216 to 240 amino acids in length. This protein has two conserved sequence motifs: VLR and TRIY. BCLP is associated with cell morphology and a regulation of growth pattern of tumor. It is found in adenocarcinomas of uterine cervical tissues.
Links
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Statistics
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PSSM-Id: 520190
Aligned: 23 rows
Threshold Bit Score: 233.7
Created: 16-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q53RY4        19 MRVGLALILVGHVNLLLGAVLHGTVLRHVANPRGAVTPEYTVANVISVGSGLLSVSVGLVALLASRNLLRPPLHWVLLAL 98  human
XP_007251987  14 MAKGLTLIVIGHINFILGAIVHGSILRHISKPSGKISTEYTVSNIIAVTSGLLSIASGIVAILVSRNITNWKLHVGLLVS 93 
XP_068070627  14 MKKGLTLIVIGHVNFILSAIVHGSVLRHVSKPSNEISTEYTVSNIISVSSGLLSIGSGIVAILVSRNIANWKLHIGLLVS 93 
XP_040024177  14 MKKGLTLILVGHINFILGAIVHGSVLRHISKPSQHISTEYTVANIISVTSGLLSIATGIIAIVVSRNLPVLRLQIGLLIA 93 
Q4RKP6        14 MRAGLTLILVGHINFILGAIVHGSVLRHISKPSSRITTQYTVDNIFSVTSGLLSILTGIIAILMTRNLRLKKLQVGLAVS 93  spotted green p...
XP_003228791  17 MKTGLILIVIGHLNFITGALVHGTVLRHIANPRDTISLQYAVSNIVTVVSAILTISCGIAAIVLSRYISRKPLAWAVFSL 96 
XP_005317826  18 MKTGLVLVVLGHVSFIIAAVLHGTVLRYVAAPRDAVALQYCVVNILSVTSAIVVITSGIAAIVLSRYLPSTPLRWTMFSS 97 
XP_001381418  18 MKTGLVLLVLGHISFIAGALLHGTALRYVTDPQDAVSLQYAVSNILAVTSAILIITCGITVIVLSRYLSLTSLRWTVFAA 97  gray short-tail...
XP_028936312  18 MKTGLVLIVLGHISFIAGALVHGMVLRYMMDTHDAVTLQYSISNILAVTSALLIISCGITAIVLSRYLSRTPLRWAVFIM 97  platypus
XP_005999296  14 MQIGISLIFIGHINFILGAIVHGTVLRHVSKPDNIITVEYCVANIISVVSGLLSITTGIVAILVSRNLSNMKLHWWMMGM 93  coelacanth

Q53RY4        99 ALVNLLLSVACSLGLLLAVSLTVANGGRRLIADCHPGLLDplVPldEGPGHTDCPFDPTRIYDTALALWIPSLLMSAGEA 178 human
XP_007251987  94 SFLNTLLSTACCVGLLLAISLTIKADGSALMQGCNSTGMPi-NA--RSPINANCPFDTTRIYDTTLSLWFPCTLLSAMET 170
XP_068070627  94 SFLNALLTLACLLGLILAISLTISGDGSALMKGCNSTNMPvnAR---SPVIVNCPFDATRIYDTTLALWFTCGAFTAVEA 170
XP_040024177  94 SFLNALLSAACCIGLLLAISITVAHNGEGLLLGCNFTDVPinAR---SPVSAKCPFDTTRIYDTTLALWIPCALLSAVEI 170
Q4RKP6        94 SFLNALLSAACCLGLLVAVGFTVANNGEGLMLGCNDTEAPinAR---SPVSARCPFDTTRIYDTALALWIPCTLLSGFEA 170 spotted green p...
XP_003228791  97 SVGSTLLSLFCSAGLAVAIVVTFANQGRTLLELCTFANVD------LIQISHECPFDPTRVYSSALALWGLSFLLDSIEI 170
XP_005317826  98 SVACALLSLICALGLLASIAVTFATQGRALLAACTFGSPE------LLALTPDCPFDPTRIYSSSLCLWGISLVFCVAES 171
XP_001381418  98 SVTSALFSLVCSLGLLASIAITFANQGRSLLATCSFSNSE------PLSLTPDCPFDPTRIYSSTLCLWAISLTLCVAAS 171 gray short-tail...
XP_028936312  98 SLTSALFSVTCALGLLASIAITFANQGQSLLATCSFSSPE------LAQFSPDCPFDPTRIYSSTLCLWGISLVLEVAES 171 platypus
XP_005999296  94 SLLNSLVSAACCVGLILAISLTVSNGGRNLLSGCNVTELQtkTK--VVVLGNDCPFDTTRIYDTTLALWVPSMLLAALES 171 coelacanth

Q53RY4       179 ALSGYCCVAALTLRGVGPCRKDGLQGQL 206 human
XP_007251987 171 GLSVWCFIIGLTLRGIGPCGHTYLKEQL 198
XP_068070627 171 GLSVWCFIVGLQLRGIGPCAQNYIREQL 198
XP_040024177 171 GVSIWCFLVGLALRGLPPCGNSYIKEQL 198
Q4RKP6       171 GLSAWCFLVGLGLRGLVPCARKYIKEQF 198 spotted green pufferfish
XP_003228791 171 IFSVRCFLIVSGLLNLKFCCKGTRKKKV 198
XP_005317826 172 VFAVRCTQLAHQLLELRPWWGKSSHHMM 199
XP_001381418 172 AFAVRAAQLTHQLLELRPWWGKRSHKLv 199 gray short-tailed opossum
XP_028936312 172 IFSVRCAQLIHQLLELKPWWGKSSTRMV 199 platypus
XP_005999296 172 AMSVRCLVVAVILRRLGVCEKDYLEQle 199 coelacanth
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