Conserved Protein Domain Family
Lipase_bact_N
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pfam12262: Lipase_bact_N 
Bacterial virulence factor lipase N-terminal
This domain family is found in bacteria, and is typically between 258 and 271 amino acids in length. There are two conserved sequence motifs: DGT and DGWST. This family is the N-terminal region of bacterial virulence factor lipase. The N-terminal region contains a potential signalling sequence.
Links
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Statistics
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PSSM-Id: 372000
View PSSM: pfam12262
Aligned: 5 rows
Threshold Bit Score: 317.571
Threshold Setting Gi: 81399160
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Q7MEB8        31 SVTFEPSVQELLGRETSINFNLKGTSASVPLPSYVLMDTTDGTLGIPTNG-----------DDALTNPRAAMNTMDGWST 99  Vibrio vulnific...
Q87HU7        31 KVTFESEVQALLDRGTSISFTIQGANADVPAPSYLLMDTSDGTLGLPTNG-----------DDALTNPRASMNTMDGWST 99  Vibrio parahaem...
WP_012600661  31 AVKYEQYIQDSLARTTSIKFHLSGANKAVPLPSFALMDTTDGTLGLPTGG-----------KDSLTNPIAAMNTMDGWST 99  Vibrio tasmanie...
Q6LP23        28 KATIDPDIEKSLKAETKINFDLLSTKKEVVTPSFLAVDSYDGTLATDGSNllsnekpdpaySTNIADPKIALGKNDGWGT 107 Photobacterium ...
Q9KL83        31 EVVYESYIQQALQRDTTIKFALSGKDANVPLPSFALMNAKDGTLEIPPGS-----------NTSGSNPLVAMGQVDGWPI 99  Vibrio cholerae...

Q7MEB8       100 SMPIVLPFEGAGFNEGILTSGVSVIK----LNQRLTdwdGQSNPID-KVLAINTDF--VVQTKGNSLFIVFKDSLNESSE 172 Vibrio vulnific...
Q87HU7       100 SMPIVLNFNGDGFAPGMLASGVKVIK----INQRLTewdGKTNPIA-KVLVQNQDY--VVQANGKSLYVQFADSLDESSE 172 Vibrio parahaem...
WP_012600661 100 SMPIVMNFEGTGLADGVATGGVYILK----LSSSLT---STTPPTVtGVLTLGTHFnvLSSAATDAFTIVFKDSLDASSE 172 Vibrio tasmanie...
Q6LP23       108 LEPITIEFKGKALTESPDPKSFVIIEsfnpTSQTDT-----TTPAA---LTYGTDY--IVTTAGQSLIVSLLKPLKANSN 177 Photobacterium ...
Q9KL83       100 TMPLFLDFKGAGLADNIITSGIYLYE----LTDSMT-----GSPSIkALLTNGVDYtaVSSAASDKILIMPTKALNASSE 170 Vibrio cholerae...

Q7MEB8       173 YIFSVSDTVLDKNGNPVGTSTSYATAKSTQVVYESGSLASVQKVTKATEGILGMA------GVIPSDIVYSSWFSTQSIG 246 Vibrio vulnific...
Q87HU7       173 YIFAVTQDVTDVNGEPIGTSSSYAVAKSKQVKYESGDLASVQAVTEAVEGIFGLA------QVNPADIVYSSWFSTQSVG 246 Vibrio parahaem...
WP_012600661 173 YVLALSNELADVNGDPVGMSSSYAALKSSSVTYTDGSLAQAQKVTQGVEQIFAGAnaagkvSLDSKDIIYSTWFTTESVG 252 Vibrio tasmanie...
Q6LP23       178 YMFAVTDALLDESNNSVGTSNSYAVLKVSNPPPSEA-LIPAQKIIHATEKTIEATt-----GTLQKDIVYSTWFTTASAG 251 Photobacterium ...
Q9KL83       171 YILAVTSEVSDANGNPVGTSASYAALKSKNKIYSEGDIATLQKVTQGVEKIFQLS------GVDETQIVYSTWFSTQSVS 244 Vibrio cholerae...

Q7MEB8       247 DTLAAVKGVTATGFSTGPNTLN--TVY 271 Vibrio vulnificus YJ016
Q87HU7       247 DTLAAVKGVTATGFATGANTLN--TIY 271 Vibrio parahaemolyticus
WP_012600661 253 GSLFATKAATATGLASAN--LN--GVW 275 Vibrio tasmaniensis
Q6LP23       252 DDLYAAKAAIALSVGSVVETGNasAIW 278 Photobacterium profundum
Q9KL83       245 NTLFATRGATASAFASGSNQLE--TVW 269 Vibrio cholerae O1 biovar El Tor str. N16961
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