6B7O,7MIS


Conserved Protein Domain Family
SidE_PDE
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pfam12252: SidE_PDE (This model is not part of the current CDD release)
Dot/Icm substrate protein
This family of proteins is found in bacteria. Proteins in this family are typically between 397 and 1543 amino acids in length. This family is the SidE protein in the Dot/Icm pathway of Legionella pneumophila bacteria. There is little literature describing the family.
Links
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Statistics
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PSSM-Id: 492486
Aligned: 29 rows
Threshold Bit Score: 138.376
Created: 21-Aug-2024
Updated: 4-Feb-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
6B7O_A         19 KTRLSQPYTEVGSEWEynyknptatfakgdghnlqryiTIDGKQLHRPIAGLAHTMRTLMYSQLMYCsskKQPSPHVCQD 98   Legionella pn...
WP_115303632  555 DNVINQPYLDEKREIT----------------------DTNGFIVYRPNHDVTHSSRKLSYKDYIIR---ALLGSTLECY 609  Legionella be...
WP_058446476   61 NNYINRPYLDIPSVIAkys----------------ynlQHDNYTVYHRNHDVTHAVRQRHYAKNYLE---IIAKYGKDEF 121  Legionella fe...
WP_058531898  138 ADIIETPYVDDPRDYI----------------------ERQNVIAYHTNHGTCHGIRQDKLSVAYLQ---LIKKQGNAVT 192  Legionella ru...
WP_058531897  129 QELIEHPYLDDPQNYE----------------------VRYNSIAFHINHGTASGLRTMILVQSGLA---LLKQWGRDEV 183  Legionella ru...
WP_058502560   68 EDMIEQPYADNPNDLIsnsn--------------------rnmVAFHENHGTAHALRQREFSKRYLS---IIQQEGTSPH 124  Legionella is...
WP_020583993  131 KHILSQPYHEEKNRQI----------------------TLNEAIVYRPNHNGTHGSRTVQYLDQIWR---LIIEKGSPES 185  Endozoicomona...
XP_005757344  206 GHHFNVPYPLPGAAPLhvppsaalpad-----apppsehgsahGVPRPNHGLANAVRKAALVRPIAKa--YASGYVGSSL 278 
WP_057625351  796 EHYLSKPYKECPsti-----------------------kiGDKNINRPNHNLPHVFRVKNAIELVIHy--FSRYAIEDDF 850  Candidatus Be...
WP_075066711  940 NKYLSKAYVEANcli-----------------------ylKGYEIARPNHNSTHTYRVMLCIEQITNy--FSHYAADEEF 994  Candidatus Be...

6B7O_A         99 GRTIad--lsELDLKKINIAQLFFVAGRESEASYGDAy---HRYHLYGAKQFEEYArkhlt--hlfseEEIRLYSRCIED 171  Legionella pn...
WP_115303632  610 QKSLke--ltPEENACLNLLIFLYRSGRTNELGSAVD----ASNAERSANLFAMVT------------LQLGFNAELVAS 671  Legionella be...
WP_058446476  122 STLAkaiindAEVKTCLELAIFLCRSGRTNEQSGRDD----PNNAKRSSELFTEVA------------TRLGFDKGLIEF 185  Legionella fe...
WP_058531898  193 LQTAns--ltSEEEACLQLAAFLFRSGRTNELGWKDD----ATYGQRSAVIFKQVA------------IDLGFNTAIVDL 254  Legionella ru...
WP_058531897  184 QTLAkn--lgTKEQSCLQLAGFLLRSGRTNELSWDDD----PTYSPRSAYVFTTIA------------HELGYDPELIKD 245  Legionella ru...
WP_058502560  125 KEAAla--mtEEEIACMELAAFMFRAGRTNERGGRGD----PSNAERSAILFESVA------------KQMGFKDDLIKG 186  Legionella is...
WP_020583993  186 KKILeq---iSSKQEVLKLAAYMMRSGRVNEAPLRVD-----NYYDRSALLFKACA------------DQLDITPENVDW 245  Endozoicomona...
XP_005757344  279 KRSDfa--fgEAQLLALELAALFGAAGRESEFSYSEDavrhTAYKKVSCDAFAAYAksiqlphrdda------------- 343 
WP_057625351  851 KEFCqe--csLEEIEWLRVAAAFSVTGRESEINAGSDleryDRYRESSATHFIDFVnktknmqlpevaHMAERVKHVVRY 928  Candidatus Be...
WP_075066711  995 KDFCqs--lnDTEIEWLRVAAAFSITGRESEISAGENltkyDEFRAASCQHFMEFVskskp---nidsRQLERVSEVVRY 1069 Candidatus Be...

6B7O_A        172 --------------------------------RVGDSFDGTPEGYIIHLSHMIDLMRCK-----SPvevflgHSKGVSGI 214  Legionella pn...
WP_115303632  672 mkmcfsylsigts-------idsyfsegytgdANVKKYKAFLVYRIANISHDLDLVRCNswryfFEtedvylKAKSLDPS 744  Legionella be...
WP_058446476  186 lafsiathkpdf---------akykdlvsklpGNDKEKLAKLLYRIIDLSHHTDLVRCK-------------TGGPDQPV 243  Legionella fe...
WP_058531898  255 itlcfdyhskn-----------ehinplpdhiMQQTRNKLDLFTSILKLSHESDLIRVN--------------MDGYAQQ 309  Legionella ru...
WP_058531897  246 iadcfdfd----------------keltsddkSPQRWHRKTLYQTLLKLAHQAELVRCK---------------PKLESL 294  Legionella ru...
WP_058502560  187 mstfmcshmpvgdwksgkinlkgaekgftavgNVTAQQKAMVMKRILDLSHHNDLVRCW-------------RDDNRTQI 253  Legionella is...
WP_020583993  246 aaqmiqe------------------sarnpelNFSRRLEDIFTRSLLSIAHECDLVRCY-------------DERKMERE 294  Endozoicomona...
XP_005757344  344 ----------------------------lqalrgafasqASAMTRVLEVAHDLDLFRCCtvaqmHP-------------- 381 
WP_057625351  929 mgnpsyekqs------------dgafginnhpDASERQRRNFYYRILSVAHKLDLPRCYtasqyEA-------------- 982  Candidatus Be...
WP_075066711 1070 mgnphye------------------dkinlhpNEHERKIRNYYHRLLSIAHKIDLPRCYsanqyHN-------------- 1117 Candidatus Be...

6B7O_A        215 VPTLIHLFGKQDG------------------LDIMHYARGLFAATGEAVP 246  Legionella pneumophila
WP_115303632  745 IKNFQFDIIKQMKiffpndr-----eaqaitNKLLILAKKSCEASGTPVF 789  Legionella beliardensis
WP_058446476  244 RKDIEHELSELLAenkvn--------vpnavSNLLTYAIQACKTTGTCVK 285  Legionella feeleii
WP_058531898  310 REPIVGELNKVLDqkndi---------gnlaDSLLLYAGQLCAETGAPIT 350  Legionella rubrilucens
WP_058531897  295 STKINVLFNDILLstcsi---------sgltGQFLLFAAVLCKNTGSPVL 335  Legionella rubrilucens
WP_058502560  254 SGPLQNQLDYLLGdtaka---------ahttKAMMNYAAQMCKATGAQVI 294  Legionella israelensis
WP_020583993  295 MGLIKTLLSPLLDrgidt---------eatiAKLINYGIELCTLTGNKLT 335  Endozoicomonas elysicola
XP_005757344  382 --KLESIKSELHTssvna---------lpadRLLFQQAVDAIRATGDRLL 420 
WP_057625351  983 ------------SmklchdlslvsdsqkndyLEMIRYNIELIKAHGGLLS 1020 Candidatus Berkiella cookevillensis
WP_075066711 1118 ------------AmkicrelsqpgeaqqtmlNEIIRYNIELIKAHGGRLS 1155 Candidatus Berkiella aquae
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