5NW5_A        138 ARRFEVYATFNNIIPILTTKN----VNEvdQKFNILIVNIEsiieiciphlqiaQDTLlSSSEKKNP---Fvi------- 203  Saccharomyces...
E1C2U2         24 PA-GDLTDAHLSLVNRLSGEEgrefVAAvrKHFPRLCKVFK-------------AHISsENSE----------------- 72   chicken
Q5UIP0         22 SH-GGQTDAYLTLTSRMTGEEgkevITEieKKLPRLYKVLK-------------THISsQNSE----------------- 70   human
XP_014352365   24 ST-AEQTDAYLTIANRLSGEEgkqfVAVveKHFSRLCKTFK-------------GNISsGNLE----------------- 72  
1_pfamImport    4 PP-TEQTDAYLTIANRLSGEDgrqfIPAvlKDVSRLSEVLK-------------GHILsRNTE----------------- 52  
5_pfamImport    4 QS--EQTDAYLTIANRLSGEEgrqfLPAveKHFSRLGKAIL-------------AHIIsPNAE----------------- 51  
XP_007253540   25 GA-SEQTDAYLTIANRLSGEDgrqfFPIivKHFSRLGKSLQ-------------THISsENEE----------------- 73  
XP_005167632   25 GL-SAQTDAYITIANRLNGEEgrqfLPVvvKHFARLSKVLL-------------VHISsENEE----------------- 73  
Q54JQ5         50 INLLKESDENGMVISVLSNSDialrFINifQTHIICCNNNQstplpnlklknnnNNNNnNNNNNNNNnngNnnsilnnqi 129  Dictyostelium...
XP_004356223   16 STGKEARDAFNQLLGLLKEHv---eNDTisQSFKLTPQTITtyikiyqyyisssNNNQpSSDN----------------- 75  

5NW5_A        204 -rLYVQIVRFFSAIMSNfkiVKWLTKrpdlvNKLKVIYRWTTGALRNENSNKIIITAQVSFLRDEKFGTFFLSNEEIKPI 282  Saccharomyces...
E1C2U2         73 --LSNAALQALGFCVFNskiTSELS------ASEVEDLLSTLNSIAVKTSDKNTRTRALWVISKQTFPSEIIKK-EVSSL 143  chicken
Q5UIP0         71 --LSSAALQALGFCLYNpkiTSELS------EANALELLSKLND-TIKNSDKNVRTRALWVISKQTFPSEVVGK-MVSSI 140  human
XP_014352365   73 --LSNAALQALGFCVFHsnvASGLA------ASEVEELLSVLSSIAAVTSDKNTCTRALWVISKQSFSPEVVGK-KVPSI 143 
1_pfamImport   53 --LCQAALQALGYCVFHssvVSGIPA-----ESKAEELLLALNTIAIKSADKNICTRALWVISKQNFSPELIGQ-KVPEI 124 
5_pfamImport   52 --LSQAALQALGFCVYHshvVSGVS------EVFAAEILSALCSLVSKATDKNTCTRALWVISKQSFPAEEVAK-KVPSI 122 
XP_007253540   74 --LSQAALQALGFCVFNtniVSGIP------AHFAEEILLALCALVLKSTDKNTCTRALWVISKQNFPAEVVSK-KTPEI 144 
XP_005167632   74 --LCQAALQALGFCVFHshiVSVIP------ANISENILSTLCNVVVKSKEKFTCTRALWVISKQNFPPEVASK-MAPEI 144 
Q54JQ5        130 dkLAINSLRSLGFFLYSssiIKCLSS-----DTQIREISTLLENTIQVTKNKNICNYAIWCFSSQSFPNGPISNKLPNTY 204  Dictyostelium...
XP_004356223   76 --LAISSLRCLGYFIYSkfiVGHLL------ENQIKDISILLENTISTTKNKNICNFAVWCLTSQAFPNGPISTKLAKTY 147 

5NW5_A        283 ISTFTEIMe---INSHNLIYEKLLLIRGFLSKYPKLMIETVTsWLPgevlpriiigdeiysmkiliTSIVVLLELLKkcl 359  Saccharomyces...
E1C2U2        144 ISTLETILtkgdVQSMIVEYEALNVVIRLMEQAPAQMGEEAVrWAK--------------------LIIPLVVHSAH--- 200  chicken
Q5UIP0        141 IDSLEILFnkgeTHSAVVDFEALNVIVRLIEQAPIQMGEEAVrWAK--------------------LVIPLVVHSAQ--- 197  human
XP_014352365  144 VSTVETLItkgdVQSLVIEHEALNVVIRLLEQTPIQMREDAVrWAK--------------------VVIPLVVHSAH--- 200 
1_pfamImport  125 LKTLEAVRaredIQSAVVEHEALNVIIRLLEQAPVQMGEGAVrWAK--------------------LVVPLVVHSAS--- 181 
5_pfamImport  123 LGTLESVWkredIHSVVMEHEALNVIIRMLEQVPTQMGEGAVqWAK--------------------LVIPLVVHSAS--- 179 
XP_007253540  145 LKTLDAMQtr-dIQSILMEHESLNVVIKLLDQAPTQMGQGAVfWAK--------------------LVIPLVVHSAS--- 200 
XP_005167632  145 LKSLEAMQtr-eVQSILIDHESLNVIIRLLEQAPVPMAVGAVcWAK--------------------LVIPLVVHSAN--- 200 
Q54JQ5        205 CDLLENTP----FNSKTIENEVLNSFTTLLQQNIQLYLNSTEiWLP--------------------IIFNKILRLENl-- 258  Dictyostelium...
XP_004356223  148 CNILETVP----FGSPTIEREVLLSFTHIYAQNPQIFLPMAHkWIP--------------------LLFDKMLANSStsg 203 

5NW5_A        360 dfvDEHERIYQcIMLSPVCETIPEKFLSKLPLNSYDSANldkvtigHLLTQQIKNYIVVkNDNKIAMDLWLSMTGLLYDS 439  Saccharomyces...
E1C2U2        201 ---KVQLRGATaLEIGMPLLLQKQQEVAAVTEHLMTTKL----------ISELQKLFST-KNETYVLKLWPLFVKLLGKT 266  chicken
Q5UIP0        198 ---KVHLRGATaLEMGMPLLLQKQQEIASITEQLMTTKL----------ISELQKLFMS-KNETYVLKLWPLFVKLLGRT 263  human
XP_014352365  201 ---KVRLKAATaLEMGMPLLLQKQQEVASITEQLMTTKL----------IPELQKLFST-KNETFVLKLWPLFVRLLGKS 266 
1_pfamImport  182 ---KVRLRAAAaLEMGMPLLVEKQQEVAAIAEPLMASKL----------IPELQKLFLS-KNESNVLKLWPLFVRLLGRS 247 
5_pfamImport  180 ---KVRLRAAAaMEMGMPLLLEKQNEVSAVIEPMMSTKL----------IPELQKLFMS-KNETNVLKLWPLFVKLLGKL 245 
XP_007253540  201 ---KVRLRAAAaLEMGLPLLLEKQQEVAAIVEPMMSTKL----------IPEMQKLFST-KNESNVLKLWPLFVKLLGKL 266 
XP_005167632  201 ---KVRLRAAAaLELGMPLLLEKQQEVAAIVEPMMSSVL----------IPEMQKLFAS-KNETNMLKLWPLFVRLLGKL 266 
Q54JQ5        259 --pNITEKLKQiLEIVVNHYQMKNNVMSERVSEVLLSNC-------NSFMENMGKLFDT-KNEILSIQCWGIYVFFTGKL 328  Dictyostelium...
XP_004356223  204 dvgKLSEEMIKrLILPAPPHELFAPEVYKELTQGLIQEI-------DVFISKLTSLND--KNELHCATIWGYFIYFLGEE 274 

5NW5_A        440 GKRvydlTSESNKVWFDLNNLCFINNH-PKTRLMSIKVWRIIT--YCICTKISQknqegNKSLLSLLRTPFqm----tlP 512  Saccharomyces...
E1C2U2        267 LHR----SGSFINSLLQLEELGFRSGS-PVVKKIAFIAWKSLIdnFALNPDILC-----SAKRLKLLMQPL--------- 327  chicken
Q5UIP0        264 LHR----SGSFINSLLQLEELGFRSGA-PMIKKIAFIAWKSLIdnFALNPDILC-----SAKRLKLLMQPLs-------- 325  human
XP_014352365  267 LHR----GGSFINSLLHLEELGFRSGS-PVVKKIAFIAWKSLIdnFALNPDILC-----SSKRLRLLMQPLs-------- 328 
1_pfamImport  248 LHR----GGPFINALLHLEELGFRSSS-PVVKKIAFIAWKSLIdnFALNPDILC-----STKRLKLLMQPLs-------- 309 
5_pfamImport  246 LHR----GGPFINSLLHLEELGFRSSS-PTIKKIAFLAWKSLIdnFALNPDILC-----SAKRMKLLMQPL--------- 306 
XP_007253540  267 LHK----GGAFINSLLYLEELGFRSSS-PNIKKIAFLAWKSLIdnFALNPEILC-----SSKRLKLLMQPL--------- 327 
XP_005167632  267 LHK----GGAFINSLLYLEELGFRNSS-PNIKKIAFIAWKSLIdnFALNPDILC-----SSKRLKLLMQPLs-------- 328 
Q54JQ5        329 IF-----VNKMANKVLGLAEKCFTHEN-KLVRIETYNSWKLLI--DSMDIEYIS-----VDKRLELFCAPFmtgftserE 395  Dictyostelium...
XP_004356223  275 LFS-----NSIINKILKLPEKWFVCLEnPELRCQTFISWRYLI--DALRQKSLV-----IPKRLNLIATPLslglkretN 342 

5NW5_A        513 YVNDPSAREGIIYHLLGVVYTAFTSNKnlstDMFELFWDHLI 554  Saccharomyces cerevisiae S288C
E1C2U2        328 -SSIHVRTEALALTKLEVWWYLLMRLG----PQLPANFEQVC 364  chicken
Q5UIP0        326 --SIHVRTETLALTKLEVWWYLLMRLG----PHLPANFEQVC 361  human
XP_014352365  329 --SIHVRTEAMALTKLEVWWYLIIRLG----AQLPVNFEQVC 364 
1_pfamImport  310 --SIQVKTEALTLTKLEVWWYLVVKLG----PHLSTNFEQVG 345 
5_pfamImport  307 -TSINVRTEALLLTKVEVWWYLVIQLG----PNLSPNFDQVS 343 
XP_007253540  328 -SSILVRTEALLLTKLEVWWYLVVKLG----PNLATNFEQVA 364 
XP_005167632  329 --SIQVRTEALLLTKLEVWWYLAVKLG----PNLSANFEQVG 364 
Q54JQ5        396 AE--------VKKTSFSTWMYFLKQFK----TQLFDVFNKVF 425  Dictyostelium discoideum AX4
XP_004356223  343 SN--------VKLNCFITWLYLLNALG----GDLPNTFHIVA 372