6YIH


Conserved Protein Domain Family
INCENP_N

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pfam12178: INCENP_N (This model is not part of the current CDD release)
Chromosome passenger complex (CPC) protein INCENP N terminal
This domain family is found in eukaryotes, and is approximately 40 amino acids in length. INCENP is a regulatory protein in the chromosome passenger complex. It is involved in regulation of the catalytic protein Aurora B. It performs this function in association with two other proteins - Survivin and Borealin. These proteins form a tight three-helical bundle. The N terminal domain is the domain involved in formation of this three helical bundle.
Statistics
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PSSM-Id: 520114
Aligned: 13 rows
Threshold Bit Score: 50.3787
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6YIH_C         2 PGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEA 37   human
XP_031800066  31 MGSASILDLCGTKLMEFMCNVENKDMVWLQEIKEEA 66  
KAI4071733     6 PGPIHLLELCDQKLMEFLCNMDNKDLVWLEEIQEEA 41  
P53352         5 TGLARLPVVCNQRLAELLRQVDDVDLLWLEEIHEEA 40   chicken
3_pfamImport   1 RGPTHLLDVCNQKFSEFLFSAEYKYLVWLREIEEEA 36  
5_pfamImport   1 EGPWRLLEVCEQRFSQFLHSAQHKHLAWLREVEEQG 36  
Q0IHP2         5 ECLSHLLQVCARKTEEFVRTLDSKHMVWLLEIEEEA 40   tropical clawed frog
6_pfamImport   1 SSTDALLQVFQGKLRDFEEEVDSKHMVWLKEIEQEA 36  
XP_040017686   6 SSVRSLMQLFDGKAQEFTNDIITVHMVWLEEIQQEA 41  
4_pfamImport   1 PSVRSLTEMFVGKTQEFINEIENVHMVWLEEIQQEA 36  
2_pfamImport   1 SSMQSLREMFVGKTQEFIDEITNVHLVWLDEIQQEA 36  
XP_007653122   6 PGPIHLLDLCDQKLLDFVCNIDNKDLMWLKEIEEEA 41  
XP_046798342   5 DGPMRLLEVCGQRLSRFLHDAEHKHLAWLREVEEQG 40   chicken
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