Conserved Protein Domain Family
STAT1_TAZ2bind

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pfam12162: STAT1_TAZ2bind 
STAT1 TAZ2 binding domain
This domain family is found in eukaryotes, and is approximately 20 amino acids in length, and the family is found in association with pfam02865, pfam00017, pfam01017, pfam02864. This domain is the C terminal domain of STAT1. This domain binds selectively to the TAZ2 domain of CRB (CREB-binding protein). In this process it becomes a transcriptional activator and can initiate transcription of certain genes.
Statistics
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PSSM-Id: 492414
Aligned: 4 rows
Threshold Bit Score: 30.3337
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_015214637 714 SRLQstETMLPLSPEDFGELTRIIN 738
3_pfamImport   1 SRLQ--DNMMPMSPDDYKALEQYVS 23 
2_pfamImport   1 SKLQ--DNMMPMSPDDYNALRQLVT 23 
NP_001012932 717 SRLQspENLLPMSPEEFDEVSRMVD 741 chicken
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