2BAF


Conserved Protein Domain Family
Fibrinogen_aC
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pfam12160: Fibrinogen_aC (This model is not part of the current CDD release)
Fibrinogen alpha C domain
This domain family is found in eukaryotes, and is approximately 70 amino acids in length, and the family is found in association with pfam08702. This domain is the C terminal domain of fibrinogen in mammals. The domain lies in the C terminal half of the alpha C region in these proteins. The function of the domain is that of intramolecular and intermolecular interactions to form fibrin.
Links
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Statistics
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PSSM-Id: 520102
Aligned: 10 rows
Threshold Bit Score: 78.3687
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2BAF_A        36 NEKVTS-GHTT-TTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDA-DFDWHH------TFPsrGNLDDF 101 domestic cattle
3_pfamImport   2 GEKDTS-GTRT-TTRHACSKTITKTVVGPDGRKEVTKEVVNSEDGADCGDIpDFNFERpegssfSFTglGSLDEF 74 
P02672       440 nEKVTS-GHTT-TTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDA-DFDWHH------TFPsrGNLDDF 505 domestic cattle
XP_007496272 381 GEKAKS-GATT-ITRRSCSKTITKTVVGPDGNKQMTKEVINSKDGDDCS---DFDFEHpeegsfTFTglSSLDEF 450
1_pfamImport   2 KEKVIS-GGLT-SSRSSCSKTITKTVIGADGRKQVTKEVVTSEDGSDCGDAtDLDSFL------T-SsrGSLDEF 67 
4_pfamImport   2 NEKVISgGGPT-ASRHSCSKTITKTVVGADGRRVVTKEVVNSEDGSDCDITtDSDSFH------TFSgkGGLDEF 69 
2_pfamImport   1 gEKVTS-GSTT-TTSRSCSKTVTKTVIGADGRKEVTEEVVTSKDGSDCGDPkDLDLFH------SLAgrGSLDEF 67 
5_pfamImport   2 KEKVTS-GGTTsTTRHSCSKTITKTVIGPDGRKEVTKDVVTSEDGSDCGDAvDLGTLH------SLPgrGGLDDF 69 
P02671       446 KEKVTS-GSTT-TTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAmDLG---------TLSgiGTLDGF 509 human
E9PV24       393 KEKVTS-SGTS-TTHRSCSKTITKTVTGPDGRREVVKEVITSDDGSDCGDAtELDISH------SFS--GSLDEL 457 house mouse
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