2BAF


Conserved Protein Domain Family
Fibrinogen_aC

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pfam12160: Fibrinogen_aC 
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Fibrinogen alpha C domain
This domain family is found in eukaryotes, and is approximately 70 amino acids in length, and the family is found in association with pfam08702. This domain is the C terminal domain of fibrinogen in mammals. The domain lies in the C terminal half of the alpha C region in these proteins. The function of the domain is that of intramolecular and intermolecular interactions to form fibrin.
Statistics
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PSSM-Id: 403400
View PSSM: pfam12160
Aligned: 12 rows
Threshold Bit Score: 87.9359
Threshold Setting Gi: 429484490
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2BAF_A         36 N-EKVTS-G--HTT-TTRRSCSKVITKTVT-NADGRTETTKEVVKSEDGSDCGDA-----DFDWHH------TFPSRGNL 98   cattle
XP_023361678  377 SgEKDTS-G--TRT-TTRHACSKTITKTVV-GPDGRKEVTKEVVNSEDGADCGDIp----DFNFERpegssfSFTGLGSL 447  Tasmanian devil
AAC67564      215 SnERATS-GssSSTsTVRRSCSKTITKTVT-GPDGHKQVVKEVVHSEDGSECPEVp----DLDSMH------SFMSRGSL 282  rabbit
XP_007496272  380 SgEKAKS-G--ATT-ITRRSCSKTITKTVV-GPDGNKQMTKEVINSKDGDDCS-------DFDFEHpeegsfTFTGLSSL 447  gray short-ta...
ELV09854      423 GkEKVTS-G--GTTsTTRHSCSKTITKTVI-GPDGRKEVTKDVVTSEDGSDCGDAv----DLGTLH------SLPGRGGL 488  Chinese tree ...
P02671        445 GkEKVTS-G--STT-TTRRSCSKTVTKTVI-GPDGHKEVTKEVVTSEDGSDCPEAm----DLG---------TLSGIGTL 506  human
NP_001258840  297 LvDKTSS-A------SSVHRCTRTVTKKVIsGPDGPREEIVEKMVSSDGSDCSHLqg-grEGSTYH-------FSGTGDF 361  chicken
XP_016083774  363 vgSKDTS-G--LFT-TKRSSCSKTVTKTIVnGPEGPKEVTKEVLTSDDGSDCSDLagvgfDLGTGG------IFNSRGTP 432  platypus
XP_023609085  367 GkEKVIS-G--GLT-SSRSSCSKTITKTVI-GADGRKQVTKEVVTSEDGSDCGDAt----DLDSFL------T-SSRGSL 430  little brown bat
ELK08295      803 GnEKVISgG--GPT-ASRHSCSKTITKTVV-GADGRRVVTKEVVNSEDGSDCDITt----DSDSFH------TFSGKGGL 868  black flying fox
XP_023412866  503 G-EKVTS-G--STT-TTSRSCSKTVTKTVI-GADGRKEVTEEVVTSKDGSDCGDPk----DLDLFH------SLAGRGSL 566  African savan...
E9PV24        392 GkEKVTS-S--GTS-TTHRSCSKTITKTVT-GPDGRREVVKEVITSDDGSDCGDAt----ELDISH------SFS--GSL 454  house mouse
2BAF_A         99 DDF 101  cattle
XP_023361678  448 DEF 450  Tasmanian devil
AAC67564      283 DDF 285  rabbit
XP_007496272  448 DEF 450  gray short-tailed opossum
ELV09854      489 DDF 491  Chinese tree shrew
P02671        507 DGF 509  human
NP_001258840  362 HKL 364  chicken
XP_016083774  433 DGT 435  platypus
XP_023609085  431 DEF 433  little brown bat
ELK08295      869 DEF 871  black flying fox
XP_023412866  567 DEF 569  African savanna elephant
E9PV24        455 DEL 457  house mouse
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