Conserved Protein Domain Family
MVL

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pfam12151: MVL 
Mannan-binding protein
This domain family is found in bacteria, and is approximately 40 amino acids in length, There is a single completely conserved residue G that may be functionally important. The domain occurs in two types of proteins. In mannan binding proteins, it forms a homodimeric molecule which complexes into a homo-octamer. In thiamidases it occurs without repeats but in the presence of other domains. MVL is distinct amongst other oligomannoside binding proteins in that it exhibits specificity for certain tetrasaccharides. Each molecule of MVL has four distinct carbohydrate binding sites.
Statistics
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PSSM-Id: 492405
Aligned: 13 rows
Threshold Bit Score: 38.5555
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_012487018   453 QSQAKQQCPSVCTNSSSFfsWNGQWTNQDAKTgqqlpMTVCGC 495 Cellvibrio japonicus
Q12NL1         531 NQAAQTVCPTVCKATNTEkvWRGEWTNTVDGS-----GAVCGC 568 Shewanella denitrificans OS217
Q73YU7          20 tGKAHASAPSFCGELGGD--WDGQYCHTSVTSe---rNAVRDI 57  Mycobacterium avium subsp. paratuberculosis
3_pfamImport     1 APPASASAPSFCSGLGGA--WDGHYCSTDVRSe---rQATR-- 36 
WP_012392159    22 APSAWGSAQSFCGELGGD--FDGRYCHTTVTSv---rKADRDI 59  Mycobacterium ulcerans group
Q63LA5         412 yRGAQAVCPTVCAAQGG---WNGQWTNQSPAApa--gQSACGC 449 Burkholderia pseudomallei
Q21NZ3         440 QPQAQTQCPTTCKTAGAl-kWNGQWTNQDAKTgkqlpMTVCGC 481 Saccharophagus degradans 2-40
jgi:Cylst_4212  38 rlDAKDKCPRTCGSVGAT--WNGQWDSNIPNQ-----SSVCGC 73 
WP_012241494   175 NADAPSKCPAACGTSRA---WNGQWSTSVAGQ-----MSVCGC 209 Sorangium cellulosum
1_pfamImport     1 -SDAQTKCPNVCNPQNMS--WNGQWWTTVPGA-----MSVCEC 35 
Q28L60          89 QNHANQVCPRLAASIRGT--WTGQWWTTQPSV-----MSVCQI 124 Jannaschia sp. CCS1
Q28L60          37 QNHANQVCPAVAASHGGT--WTGHWWTTVPNQ-----MSVCQV 72  Jannaschia sp. CCS1
2_pfamImport     1 NTHAQTQCPNTCAAYSSAtkWNGQWWTTVPGQ-----MSVCEC 38 
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