Conserved Protein Domain Family
Sox17_18_mid

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pfam12067: Sox17_18_mid (This model is not part of the current CDD release)
Sox 17/18 central domain
This is the central region of eukaryotic SOX17 and 18 transcription factor proteins. It lies just downstream of the HMG-box family, pfam00505, and is followed by a C-terminal domain.
Statistics
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PSSM-Id: 520058
Aligned: 28 rows
Threshold Bit Score: 53.8268
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q4RR75       180 FRDPAGSNS--SFDtyPYGLPTpPEMSPLDAMDHEhvpPAYYSTSasssvscsssvsCPEDvH--HQNH--TH 246 spotted green pufferfish
XP_006085339 203 YRDCQGLGAa-PLD--GYPLPT-PDTSPLDGVDPD---PAFFAAP------------LPGD-CpaAAGPy-SY 254
1_pfamImport   1 YRDCQSLGAp-PLD--GYQLPT-PDTSPLDGVEPD---PFAPRCP------------LPAD-CpaAAGAy-NY 52 
P43680       191 FRELPTLGa--EFD--GLGLPT-PERSPLDGLEPGe--ASFFPPPl-----------APED-C--ALRAfrAP 242 house mouse
XP_023350160 247 FRELHPLGA--ELD--NFGLPT-PEMSPLDVLEPSe--PAFFPPH------------MQDD-C--SLLGfrSP 297
B3DLD3       173 FRDLHPLGGsgDLE--SYGLPT-PEMSPLDVVEPSe--PAFFPPH------------MREE-A--DPGPfrTY 225 tropical clawed frog
XP_003220734 252 FRELRSVGs--DME--NYGLPT-PEMSPLDVLEQTe--PAFFPPH------------MQDD-C--NVMPfrGY 302
XP_017209261 211 FRDLHPSGa-pELE--SFGLPT-PEMSPLDVLEEGggdSVFFPPH------------MQED-V--GLSSwiNY 264
XP_015220505 202 FRDLHSVGs--EFE--SYGLPT-PEMSPLDVLEEGd--PVFFPPH------------MHDD-V--NLVPwiNY 252
XP_036734800 288 YRDCQGLGAp-PLD--GYPLPT-PDTSPLDGMEPD---PTFFAAP------------LPGD-Cp-AAGPy-SY 338 Chinese pangolin
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