7VFU


Conserved Protein Domain Family
VGCC_beta4Aa_N
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pfam12052: VGCC_beta4Aa_N (This model is not part of the current CDD release)
Voltage gated calcium channel subunit beta domain 4Aa N terminal
The beta subunit of voltage gated calcium channels is coded for by four genes 1-4. Gene 4 can produce two types of beta4A domain (beta4Aa and beta4Ab) according to how the gene splicing is carried out. This family is part of the beta4Aa N terminal domain. It is made up of an alpha helix and a beta strand. It is thought to regulate the channel properties through protein-protein interactions with non Ca channel proteins.
Links
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Statistics
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PSSM-Id: 520048
Aligned: 8 rows
Threshold Bit Score: 67.2112
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
7VFU_D        58 GSAESYTSRPSd-sDVSLEE-DREALRKEAERQALAQLEKAKTK 99  human
XP_009017056  15 GSFESNCSQNSs--NLSLEE-EQESIRKNAEKLAQTMLEKARTK 55 
EEC14293       9 GSADSNYSQPSs--DLSLDE-DRENTRRETERLALAKLQSAREK 49 
EGT32535       7 GSGDSNFSHHD---ELELEAgNRETLRRDAERQAALQLERAKYK 47 
XP_013421346  52 GSADSNYSQPSs--DLSLDE-EREALRRESERQALAKLEKARSK 92  Lingula anatina
XP_005991485  16 GSADSCTSRPSldsDVSLEE-DREVVRRDAEQHALLQLERAKSK 58  coelacanth
XP_029689745  59 GSADSYTSRPSd-sDLSAEE-DREAYRREAERQAQLQLDRAKSK 100 torafugu
XP_043911311  13 GSADSYTSRPSd-sDVSLEE-DREALRKEAERQALAQLEKAKTK 54  West African lungfish
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