Conserved Protein Domain Family
DUF3533

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pfam12051: DUF3533 
Protein of unknown function (DUF3533)
This family of transmembrane proteins is functionally uncharacterized. This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 393 to 772 amino acids in length.
Statistics
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PSSM-Id: 403315
View PSSM: pfam12051
Aligned: 26 rows
Threshold Bit Score: 198.3
Threshold Setting Gi: 148532134
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
ABN67592        6 VYISIFSVFIGILS-IYWGTLYRRDTRYKNMGFLVVSEDLPfe-vdGSRLDPFLNDAFLSMIQNNETVinl----akWEQ 79  Scheffersomyce...
Q4WCV7         14 AFVLLQLLFLANMS-YLYGSAYHDSYRISSMNVLFVDYDQG-----------VIGESVAAAYSQMQGDsf-----ptLRQ 76  Aspergillus fu...
CAK47968       34 NLLILQLLFLGLFC-YLFGSIFQQTTHIHNLNVLFVDYDGG-----------AIGRAVRTAYQQLQGAgfptlreqsAEV 101 Aspergillus niger
Q0CRK0         10 NLILLQILFLSLLC-YLFGSLYQETTHVHNINVLYVDYDGG-----------AIGDAVREAYTQLQGPgfpn-----lie 72  Aspergillus te...
Q5B7F2         84 SGIILTLLFLSLFS-YLFGSLYQLTGHTHNLNVVLVDYDGG-----------VIGDAVRQAYQQLRSDsfpt-----iin 146 Aspergillus ni...
jgi:Lreu_1896  12 LPIIVALFIGAYFS---ITAIPSTHVKVNDLPIAIVNEDSG-----------VTGENLAKQITEATSSsnssamsikWTV 77  Lactobacillus ...
Q0SEA7         22 APLLLVSVVMSLLAaLYMGGMLNPTKHLNHFPIALVNQDEG-------DTTPNSNPPQQQNFGDQIAAglve--gvdPDK 92  Rhodococcus jo...
KIS65668       71 AAMLIMVVIWTIVS-IYWGSVYKEIDLSPNLNAWVINRDTG-----------AVGSAVQQALLDTNNSaarp--rstWTV 136 Ustilago maydi...
EAW13432       47 VVLMLCVFILCILS-LYWAVQFRAEDRLPALTVWVVDFDNQvepykNDTLTAIVGPVVTDVARQAVQSnrk---gvgYTI 122 Aspergillus cl...
Q2U0W5         42 TVLTLCVFILCILS-LYWAVQFRVEQNLHSLTVWVVDFDGMvd--pYRDTKPIVGPAVTDVAENLIQTpetg--rlgYTI 116 Aspergillus or...
ABN67592       80 ITLSEFQEsarahnnnITAEVYRKVHHQKYWAAVHIKPNASQLIYRSLaTANFSLTASGEitELIDVVYESGRQYSALSQ 159 Scheffersomyce...
Q4WCV7         77 HPPSEYP---------SQYSIRQAVCEGHFWGAIYANPGASSRLSSALsSPDVAQTYDSS--QALTYVWNGVKY-ASYAQ 144 Aspergillus fu...
CAK47968      102 YP--------------NPASIVSTVCNIHYWGGFYIAANASSRLSAAL-TGIRTATYNTS--DVMTLVWNEARYSTVVDS 164 Aspergillus niger
Q0CRK0         73 RSQRDYP---------TPNDLEGTICDIEYWAAFYTSPNASDRFTAALaGGSLASSYNRS--DVLTMVWNEARYPSVSDS 141 Aspergillus te...
Q5B7F2        147 HPPSQYP---------QPAALRSTVCNIEYWGALYISGGASDRLATAIsNAQAAASYNRS--DVLTWIWNEARYPTVIDT 215 Aspergillus ni...
jgi:Lreu_1896  78 FD--------------SEKKLLKDMNREKYYGAIVIPKDFSEKLQSLTaPNAQK--------AELKIIINQGMG-TTVTT 134 Lactobacillus ...
Q0SEA7         93 VELRQI----------GIAQAQSALDNGEIYGAIVIPSDFTKRTFILA--QAGVIPGDVE--RPVITIYTNPR-AGTISA 157 Rhodococcus jo...
KIS65668      137 IDPARFPT--------QDQIDYEVTNALSTWLVVTVVENATAKLEQAR--ANGDSSWDPR--SLVSLTYATSRNFQVVPS 204 Ustilago maydi...
EAW13432      123 KSPADFDF--------DPWAVRQGVYDEHAYAAVIVNPNATALLYDAV--RNGNSSYDPS--GAAQFITISARDQTTYSS 190 Aspergillus cl...
Q2U0W5        117 KSPDEFNY--------DPWAVRQGVYDEHAYAAIIVNANATTLLHDAV--KNGNSSYDPT--GAAQFVVITARDETTYSS 184 Aspergillus or...
ABN67592      160 YVSKHISQIEDVWLS-SYVSQMIYePIIKSLNDTQRLALLANnntisILASKPAFNIIDLRPSPSSAVLGPSELGLIYAL 238 Scheffersomyce...
Q4WCV7        145 IISSSLQMLAHAATG-AYQQINGT-KAMGAVDTLNPAIAH-------TLLNPIAASSIDIKPTNQGVRFYYNTVSMVMPI 215 Aspergillus fu...
CAK47968      165 AIQSNILSLSEAARI-VYTTTNGP-SILQTVNTSDQTAIT-------TLADPWTLSTINIQPTTQGSRLIYNTLVVILIL 235 Aspergillus niger
Q0CRK0        142 VISDPIRKLSEVARI-AFTDRGGK-QMIQALNTSSPAAIS-------VLSSPWMLTSVDIQPTTQGSRMIYNTLVILLIL 212 Aspergillus te...
Q5B7F2        216 LAQQITSLSEAARVA----------YVQLNGTGAVQSLDATSpaavaAYSNPWELTSINIQPTTQGSRVVYNTLVVVLIL 285 Aspergillus ni...
jgi:Lreu_1896 135 QVNTALTQMTTQLNN-KLSTNLLQnVANRSTSIPATMAL--------NLSNPLTIKKEKVNKTGDLANGGA--------- 196 Lactobacillus ...
Q0SEA7        158 NLVQNIGEMALDKANqTMGQQLTT-QVTQQLQATAPDLQLSGas-rlVLDDPIDVRVVAHNPLPDGTGFGLAAFYYALLI 235 Rhodococcus jo...
KIS65668      205 MVLSPAMTTLNKAVA-QLSSQMAAqYLSTVAGNQTAISNLANap--qTITQPIILNQRDLRPYDVPVAIAVLVVGLIYQC 281 Ustilago maydi...
EAW13432      191 YIDPALSSFQLAALA-EFGPKWVQ-TLAAQSVNISRVPQ--------AVNPAIGFQQVDLRPFGPAAATPSVTIGLIYLI 260 Aspergillus cl...
Q2U0W5        185 YITPGLTAFASTVLA-EFGPRWVQ-TVAQESLNISNVPQ--------AINPAIGFNTVDLRPFGPAAATPSVTIGLIYLI 254 Aspergillus or...
ABN67592      239 LFSFHQ---------FNFSLEIYNYI-----RTKL----KFRHY------LVWRFVASQINCLVLALVYSLIT-IAFQVP 293 Scheffersomyce...
Q4WCV7        216 LQQFFF---------IMALNGLTAEFgv--vLRTM----SLRGS------IVLRLTLSVLYTFIAALCMTGYI-WGFREA 273 Aspergillus fu...
CAK47968      236 IQEFFY---------LGYLNGLYQQFh---lYTSV----DAHRI------AIIRQLISGIYTFIGSLCTTGAI-WAFRYG 292 Aspergillus niger
Q0CRK0        213 IQEFFY---------LGCINSLYLQFr---lYTAV----SPHRI------VVVRIIISAVYTFIGSLCVTGAI-WAFRNG 269 Aspergillus te...
Q5B7F2        286 IQEFFF---------LATINGLYVQFg---iFRRI----NPKRM------IVFRFIISAVYTLAGSICATGAI-WAFRAG 342 Aspergillus ni...
jgi:Lreu_1896 197 --HFFQ---------SVWLGSLGTSMllgfaFSKI----RFKSLkekfsaLFVQLIAAGISALVIGYGVPALQsWILDVN 261 Lactobacillus ...
Q0SEA7        236 VLAGFTgatiastliDGMLGFTPTEVgplylHNEAvpisRFNTL------LI-KWAVMVVLAMIVSGLYLWIS-SALGLP 307 Rhodococcus jo...
KIS65668      282 ILAFVF---------TMANFGARQAL-----QPYL----RFRSL------VAMRFAAPLVCYFFLSLMISLLN-IPFEVP 336 Ustilago maydi...
EAW13432      261 IIAFFN---------FPFLMPVHVQLik-gdHPPL----KGPQW------LLWRLCSNITAYFFLSLFYSFVS-LAFQVP 319 Aspergillus cl...
Q2U0W5        255 IIAFFN---------SPFLMPIHAQFlk-gnHPPL----KIPQW------LLWRVCSNITAYFFLSLFYSFVS-LAFQIP 313 Aspergillus or...
ABN67592      294 T-------------NVAFGH-SGFVVLWMFMYLYISASGGINENVVTVIlafdQKVFLAPWMIFNIVINISS--TFAPFV 357 Scheffersomyce...
Q4WCV7        274 W-------------AVTGGQ---FALTWMAIWLVMHLNFLLIDAVTSVL----PMKFMPFAILTWIIINVSS--TIGPFD 331 Aspergillus fu...
CAK47968      293 W-------------HVNGGQ---FMITWMALWLFAHLNFLVLDVFTIWL----APPFVPMALISWVVLNVSS--ILLPFE 350 Aspergillus niger
Q0CRK0        270 W-------------HVDGSQ---FMLNWMILWLFAHLNFLTLDVFSIWA----PPPYVPMALITWIVLNVTS--ILLPFE 327 Aspergillus te...
Q5B7F2        343 W-------------QVNGNQ---WALTWITLWLFAHLNFLTLDVFAVWL----PPPYVPMSLITWVVLNITS--ILVPFE 400 Aspergillus ni...
jgi:Lreu_1896 262 I--------------------PNFTELGLFMSLCAFAFIIFINGVESWV----GIISIPVFMLLLFFAAPLL--TAVPES 315 Lactobacillus ...
Q0SEA7        308 I--------------------TDPLALWEYGAFAIAAVGITAMSVMAAF----GNLGLLINLLVFVVLALPSsgGTIPLE 363 Rhodococcus jo...
KIS65668      337 F-------------GRTFSYgAGFMTWWCATFIAMCVLGFVTECFISIV----GPRFIGFTLVFWIIINVSV--ANLPIE 397 Ustilago maydi...
EAW13432      320 FsnhpasetllvsnPNAYGH-GSFVVFWMLNWVGMAALGLPCENMGMIL----GFPWSALFLIFWVISNVAT--GFYALD 392 Aspergillus cl...
Q2U0W5        314 FsnspapdtvsasnPNAYGH-GSFVVFWMLNWVGMSALGFPLENMAMVL----GFPWSSLFLIFWVISNVAT--GFYALD 386 Aspergillus or...
ABN67592      358 LMPGFYRYGFAL-PMYNTYEALKVV---FFDTWK-GNLGRNLGVLVIWIVVMNI 406 Scheffersomyces stipitis CBS 6054
Q4WCV7        332 LSPGFYRLGYAL-PAYELYQLLLDI---WTEGCN-PPLYRELPILFAWWVVGFV 380 Aspergillus fumigatus
CAK47968      351 LSPGFYKWGYAL-PAHAIFQVMVDI---WSGGCN-PQLDYALPVLFAYEVVGMV 399 Aspergillus niger
Q0CRK0        328 LSPAFFQVGYIF-PAHSVFQVLMDI---WSGGCN-PQLNYALPVLFSWEILSLA 376 Aspergillus terreus NIH2624
Q5B7F2        401 LSPAFYKWAYAL-PAHACFNILIDI---WSGGCN-PQLGYALPVLFAYELSSGI 449 Aspergillus nidulans
jgi:Lreu_1896 316 LN-GFYSTLADWlPMSYMYRGVKSImyfNHGPANsVVMGLIYTIITGLILIITA 368 Lactobacillus reuteri DSM 20016
Q0SEA7        364 AAPRLYTWLGEFePMHQIYIGVRAIm--FFGAAGdAGLIHAVWMTLAGLLIGLV 415 Rhodococcus jostii RHA1
KIS65668      398 LSPSFYKYGYSM-PFYSIRQIYVKI---IFDVGErVEMLKWFGILWAWLAVVML 447 Ustilago maydis 521
EAW13432      393 LAPAFFRWGYAW-PLHRIVEALRTI---LFDTHS--RIGLDFGVLFAWVGVSIL 440 Aspergillus clavatus NRRL 1
Q2U0W5        387 LAPGFFRWGYAW-PLHRIVEALRTI---LFGTHS--RIGLDFGVLFAWIGVSIL 434 Aspergillus oryzae
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