Conserved Protein Domain Family
OrsD

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pfam12013: OrsD 
Orsellinic acid/F9775 biosynthesis cluster protein D
This family of proteins is functionally uncharacterized. This protein is found in eukaryotes. Proteins in this family are typically between 247 to 1018 amino acids in length. Family members include orsellinic acid/F9775 biosynthesis cluster protein D (orsD) from Emericella nidulans. The orsD gene is part of the cluster that encodes components for the biosynthesis of orsellinic acid, as well as biosynthesis of the cathepsin K inhibitors F9775 A and F9775 B, but the function of orsD is unknown. OrsD contains two segments that are likely to be C2H2 zinc binding domains.
Statistics
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PSSM-Id: 371847
View PSSM: pfam12013
Aligned: 13 rows
Threshold Bit Score: 121.019
Threshold Setting Gi: 154271276
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
KIS69153        4 DDFIYNAEHGVVVCRS--CATCLVPreQSWRHHLRAKPHELLRE---SLQRTVDHLa-tYSLRSSDelRAQAKNASRQP- 76   Ustilago mayd...
Q2UV83          2 DLFMYNETYCLWICTS--CHYAVTP--QHLDRHLRTHHRQHPSVktaELRQAVLTE---MLKKPWI--EPRKEPSRFPS- 71   Aspergillus o...
Q0CCU7          2 DLFTYYEPSRVWICKP--CQFAVPP--RHLQEHLRTRHSTHPTAttgALRQDTYQR---MSKRPWL--DPTREPCIYPD- 71   Aspergillus t...
Q4WL58          2 DLFLYNPTYQVWICTAprCQYAVSP--RTLLGHLRTRHRSHPTVatpALCQAVLTE---MLQRPWA--DPSQGPCPQPS- 73   Aspergillus f...
XP_001536491    2 DLFIYNRSHRLWICRP--CGFAVAV--ANVLTHLAKRHRNHPSAataGLREAAVAAmmqDQLEPVF--DRTQEPCCPPP- 74   Histoplasma c...
KIS68295        4 DNFAYDADHRVIVCRI--CQSCILPkeQSWSTHLRSKPHHMKGD---ELQRTIDHFs-sYDLRTFDe-lRDRTARSWRKv 76   Ustilago mayd...
KIS68052        4 DTFHHNPEHGVIVCRQ--CETCLMPreSSWVGHLRIRPHHMKGE---HLVRTLEHFhsfGNFSSVDdlRQRAAARRRQD- 77   Ustilago mayd...
CAK43688       20 QLLHYLPDYQVVICSA--CRYAVQP--HGILRHLKEIHRIL-RGrrrKYSHYV---------ASLS--LREPNDVIPPSg 83   Aspergillus n...
Q2GSC4          9 DLLAYNAKHRVLICRE--CQYAIQK--SALGSHLL-RHKVYRREr-qRLLSAI---------AQLE--ILEPDDVQLPS- 70   Chaetomium gl...
Q5AUW7         10 KILEYDGRYGVLICHE--CRYAIQK--SALQSHLL-RHKIY-RAdrqQLVAMI---------NELD--LLEPDDVLLPP- 71   Aspergillus n...
EDN05500       62 QLFIHCESYLIIICRR--CKHAVWP--TEIERHLKGKAHQLKHAvvqQIKENI---------EQWDnvARDTTQLTLPT- 127  Histoplasma c...
Q0CZA1          1 MLFERIPRLQVMICRQ--CRYGVWP--AEAERHLK-RHHQLDHQtvrPMLQSI---------AQWTdvARNSQAVDIPH- 65   Aspergillus t...
Q5B2Y8          4 LLFETIPELQIMVCRQ--CKHGVHL--IEVETHLYRKHFMT-SLqiqPVLETV---------QQWTnlIRDPGAVEIPR- 68   Aspergillus n...
KIS69153       77 HPCQVIPGLALY-DGFIChcapGDCTYMTRRIKLMRDHLTVHDN 119  Ustilago maydis 521
Q2UV83         72 PDSPPIPHLPIY-SGLRC----PRCSYIGRSSNTLRNHLSHSHP 110  Aspergillus oryzae
Q0CCU7         72 AGSPPIPHLPVY-TGYQC----PRCRYIVRAPRVLFNHIRKTHP 110  Aspergillus terreus NIH2624
Q4WL58         74 TGDPPVPGLPVY-QGRGC----PHCPYICRALAGLQDHRARKHK 112  Aspergillus fumigatus
XP_001536491   75 PESAPVPGLPVY-RGYRC----PHCPYVSRTLGAVSKHQPKAHP 113  Histoplasma capsulatum NAm1
KIS68295       77 TSCPPIQGLQTH-DGYTCvcvkDKCNFSTLRELTIRSHVATHGM 119  Ustilago maydis 521
KIS68052       78 QPCRPVDGLALY-EGFICtc-tATCFFSTRRLDKIRKHIC-VHG 118  Ustilago maydis 521
CAK43688       84 ADQFPVPYLPVE-PGLQCq--sAGCKYLCASNKRMQSHWRTVHG 124  Aspergillus niger
Q2GSC4         71 ASSLPVEGLPTI-SGYGCt--aAGCGNLCASSKRMRRHWSEKHG 111  Chaetomium globosum CBS 148.51
Q5AUW7         72 PESPPIDGLPVI-AGYRCt--aPGCANLCASLKRMKGHWRESHG 112  Aspergillus nidulans FGSC A4
EDN05500      128 ILNEPIPELPIQ-DGYRCqr-dPQCQYVAGNMNTMRKHWQNKHS 169  Histoplasma capsulatum NAm1
Q0CZA1         66 CLDEPLPIIPCFsQGLLCrrdpATCHYLVANMKSMRKHWQAVHQ 109  Aspergillus terreus NIH2624
Q5B2Y8         69 ALDHPLPILPVStNGMQCrr-dLDCPYIATNLNTMHNHWQQVHG 111  Aspergillus nidulans
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