pfam12008: EcoR124_C (This model is not part of the current CDD release)
Type I restriction and modification enzyme - subunit R C terminal
This enzyme has been characterized and shown to belong to a new family of the type I class of restriction and modification enzymes. This family is involved in bacterial defense by making double strand breaks in specific double stranded DNA sequences, e.g. that of invading bacteriophages. EcoR124 is made up of three subunits, HsdR, HsdS and HsdM. The R subunit has ATPase and restriction endonuclease activity. This domain is the C terminal of the R subunit.
Jiyao W et al.(2023). "The conserved domain database in 2023.",