3PVS


Conserved Protein Domain Family
MgsA_C
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pfam12002: MgsA_C (This model is not part of the current CDD release)
MgsA AAA+ ATPase C terminal
The MgsA protein possesses DNA-dependent ATPase and ssDNA annealing activities. MgsA contributes to the recovery of stalled replication forks and therefore prevents genomic instability caused by aberrant DNA replication. Additionally, MgsA may play a role in chromosomal segregation. This is consistent with a report that MgsA co-localises with the replisome and affects chromosome segregation. This domain represents the C terminal region of MgsA.
Links
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Statistics
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PSSM-Id: 520015
Aligned: 521 rows
Threshold Bit Score: 173.69
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
3PVS_A        268 GSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSN 347 Escherichia coli
WP_022132589  257 GSDENAALHYLARLLEAG-DLISPCRRLLVIASEDVGMAYPMCAVIVKACVDSALQLGLPEARIPLAQAVVTMATAPKSN 335 Negativibacill...
CDF01241      254 GSDENAALHYAARLIEAG-DIISLSRRLLVIAAEDIGLAYPQAISIVKACVDSALQLGLPEARIPLSEAIILLATAPKSN 332
CDE77838      254 GSDENAAVHYAARLIEAG-DIISLSRRLLVIAAEDVGLAYPQAIPIVKACVDSAMQLGLPEARIPLGDAVVLLATAPKSN 332
WP_015557218  253 GSDENAALHYTARLLEVG-DLLSLVRRILVIAAEDVGLAYPQAMPIVKACVDAALQLGLPEARIPIAEAVILLATAPKSN 331 Ruminococcus
42_pfamImport   1 GSDENAALHYAARLLAAG-DLLSICRRLLVIASEDIGLAYPQAIVITKACVDSALQLGLPEAQIPLAEAVVLLATAPKSN 79 
CDD02520      246 GSDENAAIFYLARLLEGG-DLLSPCRRLLVIASEDIGLAYPQAAAITNSCVESALKLGLPEAAIPLSEAVIMLATAPKSN 324
CDE05654      258 GSDPDAAVFYLVSLLEYG-ELLSVCRRLQVMASEDVGLAYPAAASAVRAMCESAKEVGMPEARIPLANAAVLLATAPKSN 336
CDC63342      247 GSDPDAAVFYLGRLLASG-ELLSACRRLQVIAAEDIGLAYPQAIPIVYAACQSAVSLGMPEARIPLADAAILLATAPKSN 325
CDB02863      254 GSDPDAAIHYFARLIDGGSDIQTIGRRLLVMASEDVGMAYPSAVSIVNSCVQASMMVGLPEAAINLSQAVILLAAAPKSN 333

3PVS_A        348 AVYTAFKAALADARERPDYDVPVHLRNAPtklMKEMGygqEYRYAHDEaNAYaAGEVYFPPEIaq--trYYFPTNRGLEG 425 Escherichia coli
WP_022132589  336 SSYMAINQAIADVRAGKIGDFPRCLQNKHfdgAEVENkgqFYKYPHDYpDHY-VRQQYLPDILqg--tvYYHFGQNKTED 412 Negativibacill...
CDF01241      333 SAESAIDAAIVDLKSCDALDFPRHLQNKHydgEGAAIkgqHYIYPHNYkNHY-VKQQYLPDALkd--hiYYSFGENKQEQ 409
CDE77838      333 SGYMAINSALEDVRTKECGDFPRHLQNKHcdgEDAQVkgqHYLYPHDYpNHY-VKQQYLPDPIkd--rvYYHFGENKSEQ 409
WP_015557218  332 SAYLAIDAAAADLQRGTTCEIPRQLQNKHfdgADAKVrgqHYLYPHDYpNHW-VKQQYLPDELkd--rvYYQFGQNKQEQ 408 Ruminococcus
42_pfamImport  80 SAYLAMHRAMEDVEKHGALDFPRHLQNCHfdgAGAAVkgqHYLYPHDYpNHY-VPQQYLPDEIrd--avYYEFGTNKQEQ 156
CDD02520      325 SAYMAYANAKADIDAGRGANVPTHLRDKTtpsDSVka--aKYIYPHGHpNNY-VKQQYLPDDLtd--rrYYTYGDNKQEK 399
CDE05654      337 SSYLAAAAALEDFNAGRGKIPPEPLRAPLyr---------gYVYPHDYpGHY-VKQQYLPDDLad--rvYYKFGDNKTER 404
CDC63342      326 SGDAAVTMAMADAEKGMGGQVPVHLRAPLyq---------gYRYPHDYeNHY-VAQQYLPDDLrd--rrYYTYGNNKTEG 393
CDB02863      334 SAIAAFERASEDIRNRTTDDVPDHLKDNHykgAEKLGigvTYKYPHAY-GGY-VKQQYLPDDLyregvkYYTPTENGSES 411

3PVS_A        426 K 426 Escherichia coli
WP_022132589  413 A 413 Negativibacillus massiliensis
CDF01241      410 A 410
CDE77838      410 A 410
WP_015557218  409 A 409 Ruminococcus
42_pfamImport 157 A 157
CDD02520      400 A 400
CDE05654      405 A 405
CDC63342      394 A 394
CDB02863      412 S 412
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