Conserved Protein Domain Family
NiFe-hyd_HybE
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pfam11939: NiFe-hyd_HybE (This model is not part of the current CDD release)
[NiFe]-hydrogenase assembly, chaperone, HybE
Members of this family are chaperones for the assembly of [NiFe] hydrogenases, in the family of HybE, which is specific for hydrogenase-2 of Escherichia coli. Members often have an additional N-terminal rubredoxin domain.
Links
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Statistics
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PSSM-Id: 519975
Aligned: 34 rows
Threshold Bit Score: 104.667
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_011714117   6 LMQQLETTFTAIHKNQMQGIPLLNPMIRVEAVGFQRWqVGWLGVVITPWLMNLVYIP-----DD-ASALEAAPLGDKQVH 79  Magnetococcus m...
WP_002443832  14 PGPQLAAWYQEHAAPRMADLPFYRADMPIQCCDFQRFeGQWVGTLLTPWMLELVVMP-----GP-GQVWDERPTGEALGL 87  Shimwellia blattae
WP_263066062  18 PVVWLEAEFSRIAQERMRLLPFYRDGIPVRACGFTLFeQQWFGCLLTPWMLSLLVLP-----GP-GQQWPRRDLATRLAL 91  Dickeya dadantii
Q6D7U5        12 PAAQLETAFQAIAEREMQSLPFFQPQIPVSACGFQLFeHQWIGCMLTPWMLSLLVLP-----GP-DQCWLRRTVGESLGL 85  Pectobacterium ...
WP_011706345  28 PAPLLVAQYERIAQQEMQALPFYHPAMPIVAEC-TLFeGQWLGCVLTPWMLSVVVLP-----GP-DQLWPVRGSSDRLAL 100 Aeromonas hydro...
WP_012073019  24 PALLLQTEMER-TRPNMRSLPFFRENIPCYCPPFILLdNQWIGTVLTPWMLSLVILP-----GP-NQEWETRPLGDKLGV 96  Actinobacillus ...
Q8ZM18        12 PVARVQAAFEEIAHRSMHDLSFLHPTMPVHVSDFTLFeGQWTGTVITPWMLSALIFP-----GP-DQIWPRRTVGEKLGL 85  Salmonella ente...
2_pfamImport   1 PRMQVQAAFEEIARRSMHDLSFLHPNMPVYVSDFTLFeGQWTGSVIAPWMLSALIFP-----GP-DQLWPVRKVSEKLGL 74 
3_pfamImport   2 PTEQIRNAFEKVAADTMHDLTFLHPSMPVYVTELTLFeGQWTGCVITPWMFSAVIFP-----GP-EQLWPQRKVSEKIGL 75 
WP_015279921  22 LTSAVIAAHQAVLREQLAGDPLLNPALGMEVRAYREVe-DWRALLLTPWMLARRFFPqqvpdLPlPPNWSATNRREADYL 100 Thioflavicoccus...

WP_011714117  80 RF-PERSYTMLVNDFAG-------VGRCWSFSIHSPMGEFPAHDAAVARAEAFLALLLTPQQgeepqddaldeariqril 151 Magnetococcus m...
WP_002443832  88 AF-PAGDIRFRVSSPQP-------DLPLLSCSLLSPLPATLSPEQAQTIARDALRLLLALPVtepa-------------- 145 Shimwellia blattae
WP_263066062  92 DL-PCGSVKFVVSESDD-------GRQYLSCSLMSPLDSMLDAGQALQLAQQSARMALSLPVcdada------------- 150 Dickeya dadantii
Q6D7U5        86 SL-PCGDIRFTVGYVDG-------CGQYLASSLMSPLNKTLTAESMLSLAEQTVRMALSLPVvdgnm------------- 144 Pectobacterium ...
WP_011706345 101 QL-PCGNLTFMVGALPE-------TGQLLACSLMSPIDPHLGADEGRALVSSTLKMLLSLPVqqgeg------------- 159 Aeromonas hydro...
WP_012073019  97 AL-PYKTLMFTVSQLEG-------IPCYLSHSLASPLARKLTAEQGVQLADDCLKMALSFPLnqpq-------------- 154 Actinobacillus ...
Q8ZM18        86 QL-PYGTMTFTVGELEG-------VSQYLACSLMSPLSRSLSPEEGVRLADDCARMLLSLPVsnpd-------------- 143 Salmonella ente...
2_pfamImport  75 RL-PYGAMTFTVGELDG-------VSQYLSCSLMSPLNHGMSAQEGMRLADDCARMLLSLPVsdpda------------- 133
3_pfamImport  76 RL-PYGIMTFTVGELEG-------VSQYLACSLLSPLPHTLSPQEGMRLADDSARMLLSLPVtdpda------------- 134
WP_015279921 101 ILgPTMRFELLGQTQQghlgyrstLGHYLLQPLCLDMSSYRDAEA----VFAAWSEVIRTRNanmertrr---------- 166 Thioflavicoccus...

WP_011714117 152 stddiralyeeeqakvmeeaglvskqgsqacpatqtgaepmgermqqpmSRRALLPG 208 Magnetococcus marinus
WP_002443832 146 ---------------------------------------------aldtSRRALLTG 157 Shimwellia blattae
WP_263066062 151 ---------------------------------------------penlGRRALFSR 162 Dickeya dadantii
Q6D7U5       145 ---------------------------------------------pasrGRRAFFhl 156 Pectobacterium atrosepticum
WP_011706345 160 ---------------------------------------------gvnlSRRRLFSG 171 Aeromonas hydrophila
WP_012073019 155 ----------------------------------------------pdlKRRNIFRS 165 Actinobacillus succinogenes
Q8ZM18       144 ---------------------------------------------apqtSRRALLFG 155 Salmonella enterica subsp. enterica se...
2_pfamImport 134 ---------------------------------------------pqlaGRRALLFG 145
3_pfamImport 135 ---------------------------------------------pamaGRRALFTG 146
WP_015279921 167 -----------------------------------------dcrmqrevSRRELFgr 182 Thioflavicoccus mobilis
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