Conserved Protein Domain Family
DUF3418
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pfam11898: DUF3418 (This model is not part of the current CDD release)
Domain of unknown function (DUF3418)
This presumed domain is functionally uncharacterised. This domain is found in bacteria. This domain is typically between 582 to 594 amino acids in length. This domain is found associated with pfam07717, pfam00271, pfam04408.
Links
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Statistics
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PSSM-Id: 519950
Aligned: 183 rows
Threshold Bit Score: 461.977
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
WP_012876860     879 KQGAAMATEKVLLYGVPIVSDRPVLFARVDPE---AAREMFIRHALVQGEWtthHTFFAENRRLLEEAEQVEARSRQRGL 955  Xylanimona...
WP_013042930     695 KAAAAQCKQRKLLFGLEL-SRRHVSLTPIDPK---ESTDIFVRNGLIEQGIheqPGFLKHNADICEEAVSELARRRMGSG 770  Coraliomar...
jgi:DaAHT2_0729  697 RRGQVVAKEKGTLFGLVVVAGRKVPFARIDPA---EARRIFIQSALVEGELkgnYHFLGHNRQLLADLKDLEERSRRRDL 773 
WP_015405382     641 KSGQVVADEKISLFGLILSADRTVNFGRTGKKnqkEARQIFIQHALLENDIqgnYSFLQNNIDILKKWQDTEERLRKRDL 720  Desulfocap...
Q6AL39           645 KTGQVIADEKVTLFGLVLLASRRVNFGKRDKKnraEARRIFIESALLSGDLwgkYPFLKNNLTLVSQWQETEERLRKRDI 724  Desulfotal...
Q2LSZ0           690 RREEVVAYQQVSLFGLVIVPQRKVSYAHIDPE---EASRIFVRSALVEGELktpLPFLLYNRQLVAEVIGMEDKIRRRDL 766  Syntrophus...
WP_015948622     766 NRGEVIAKEQVSLMGLIIIAGRPTSYGPINPQ---EATELFIQGALVECQTnekFGFLAHNQKVLNEARDMEERLRRRDL 842  Desulfatib...
WP_012174408     716 SREEVVADCRTTLFGLTVDFRESVSYGRVDPA---GAADIFIRSALVNGDVkqpLSFMAHNTRLIEEGVEIENRLRRKTF 792  Desulfosud...
WP_015905566     739 QRGEVVATEQISLFGLVIVPERTVAYGKINPR---EAGEIFIRQALVEQEVarpLGFMVHNQALIDELRQVEEKTRRRDI 815  Desulforap...
WP_277002314     743 KRGEVVASEQVSLFGLILASGRSVAYGKINPE---ESGELFIRHALVQGEIyqeFGFMTHNRNLIEEIATLEDKTRQRDI 819  Desulfobac...

WP_012876860     956 VASEDDLFAFYDERVPASVVSARHFDQWWSRARRETPDLLTFRLEDLV--DVDAVDPSQFPSSWtqG-E-LTLPLTYQFR 1031 Xylanimona...
WP_013042930     771 LTVEDRLFDFYRSRLNA-CGSYAELRRFAKEQFGGKLDFLKARIDDLLpeATDSSLGEAFPKQV--QiGgSTLPLHYRHD 847  Coraliomar...
jgi:DaAHT2_0729  774 LVADDRIFQFYEQRLPPEVCDQASLNRLLKK--RRGDTFLQLQREDLLyrEPKADLMEQFPTAM--QvGqISLQLSYHFE 849 
WP_015405382     721 VVDDTSLRNFYDARLPADVYDRFTLNRFLSR--NKDQSFLNMKEEDILarRPEDRELQDFPKEL--RmGsHTLQLSYNLT 796  Desulfocap...
Q6AL39           725 VYSDTALHQFYQDRLGEDVYDRTSLEKFLKQ--TEDKKALFMTEQDILrrTPETSEYADFPTTI--QiGsLSLKLSYTFD 800  Desulfotal...
Q2LSZ0           767 LQDESVLNDFYASRLPG-ICNVRTLKRKIRE--QGGDAFLRMTPADVLtrLPDEEELSLFPDEV--TvGgRSYRCVYRFD 841  Syntrophus...
WP_015948622     843 VVDELGISRFYEQRLDT-VYSIQSLKKIIKD--KGGDSFLRMDVTDVMvrSPEAEDLSQYPNRL--KvDgAKFKLQYRFD 917  Desulfatib...
WP_012174408     793 LAGDDDLFAFYRQRLDNDVYSMRTLKKRIAE---QGVDFLKMSRADVIkeEPDPEEMAGFPDTL--HlGrEQFACLYAFD 867  Desulfosud...
WP_015905566     816 VVTEDDMFLFYQQRLDQDFSNLATFTRFLKE--QGSDLFLRMTLEDLQqrSPDRDELLKFPDSL--EmGgGSFRLEYGFQ 891  Desulforap...
WP_277002314     820 LASDDEIYLFYQSRLPKPFYNIRTFAKFIKD--KKDDTFLRMTREDLQktDVDEALLARFPDTL--TtDqGEFALDYEFN 895  Desulfobac...

WP_012876860    1032 PGSDADGVTVHVPLSVLPRLSPSGFDWMVPGLLEELCVATIRSLPKAVRVQLVPAPDVGNAVAgwlrQNTPTWEDmarag 1111 Xylanimona...
WP_013042930     848 PGGDADGVTVQVPINQLGAIQEGILDWAVPGHLEEKVESLLRGLPKQIRISLHPLKERASEISkqikASDR--------- 918  Coraliomar...
jgi:DaAHT2_0729  850 PGAEDDGLSVLIPVQLAAHLRPERFEWLVPGMLEEKIFFLLKNLPKNLRRQLVPIPRTAAELAeklhEKLQSVn------ 923 
WP_015405382     797 PGKEDDGVTVRIPVDGVENFSESVFEWLVPGLLREKVNFLLKGLPKRLRKHLIPIPNTVDLLLddcnHYQG--------- 867  Desulfocap...
Q6AL39           801 PRGNRDGLTVHIPVDLADTISPGRFDWLVPGFLKEKITFLLKGLPKSLRKKLVPINSSVDRIMddisTKAQSPSG----- 875  Desulfotal...
Q2LSZ0           842 PGKADDGVTLKIPDVLLPDVPAAAADWMIPGHLRDRILALLRGLPKEYRKKLQPLAGTADYIVkhlgGPSG--------- 912  Syntrophus...
WP_015948622     918 PGRPGDGVTIKIPQPLVSSVPPEPLEWVVPGLLPEKVTAMIKGLPKPLRVKLVPVNKTVDRVMdkldKYKHL-------- 989  Desulfatib...
WP_012174408     868 PAKDEDGVTVRIPAHRAPDVDPDHLDWLVPGLLTEKIAALVKGLPKAYRKQLVPISRTVEIITtempQRKR--------- 938  Desulfosud...
WP_015905566     892 PGAETDGVTVKVPATSAASVSVSTIDRLVPGLLTEKIAALIKALPKRFRVRLVPVADTAAMIAdslpESDR--------- 962  Desulforap...
WP_277002314     896 PGAKTDGVTLKVPSQDAALISPHQVETLVPGLLREKIAALIKALPKSHRVKLMPIQQRADFIAdhlpDSDA--------- 966  Desulfobac...

WP_012876860    1112 dmaePFHVAFTRAVRALRDVVVPGDAWDterVER-LPAHLRMTFRVV-EsgvksggpttaagsrgsgRGGrgrgrdgrgs 1189 Xylanimona...
WP_013042930     919 ----PLRETLSAYLQAEYRILTNRDDWS---RTE-IPDYLKPRIQVR-Tk-----------------QGE---------- 962  Coraliomar...
jgi:DaAHT2_0729  924 ---iSLYQALGQEIYHRYGLRIEAAAWP---IKA-LPDHLRCRFCLV-Nq-----------------EDK---------- 968 
WP_015405382     868 ----SLYHALERGIFKMFRLRVGRSDWP-----EiLPSHLTMRYLLY-Dt-----------------SGR---------- 910  Desulfocap...
Q6AL39           876 ----NMLSCLESSILKLYRFNLQRSDWP-----QeLPHHLTPYFVLEaD------------------SGK---------- 918  Desulfotal...
Q2LSZ0           913 ----PLLSAVAGLLRERLGVDIPASAWS---ARE-VPDFLQVRFAVV-Dg-----------------EGR---------- 956  Syntrophus...
WP_015948622     990 ----SMGAALSHAIHETMDIEIPAISWP---GPSdLPPHLTARLAVT-Ds-----------------KGR---------- 1034 Desulfatib...
WP_012174408     939 ----PLVSALSLFIRKRFGVEVPASAWQ---PEK-LPEHLHARIAIT-De-----------------RNR---------- 982  Desulfosud...
WP_015905566     963 ----PLFVELSHFIKQRFKVDIPPSAWS---DAT-LEEHLKIRISIT-Da-----------------KGK---------- 1006 Desulforap...
WP_277002314     967 ----PLYSKLSGVIQKHFNLVIPASAWS---DED-LADHLKMRISIR-Dh-----------------KDR---------- 1010 Desulfobac...

WP_012876860    1190 psaaaavspsgtgaagaAIDESKDLLALQRRLA--------PKA---EAAVRAAVKGAVavaleearsrtaalsaggsae 1258 Xylanimona...
WP_013042930     963 -----------------VLAEGRNLESVRQELN--------AVE---QSVSQGSGLNSMpawqq---------------- 998  Coraliomar...
jgi:DaAHT2_0729  969 -----------------ILASGRNLSALASGGPpa-----aPPP---DKVVAALRQ------------------------ 999 
WP_015405382     911 -----------------TVATGRILHKLAHSVS---------SAspcKITPDKKTQNSLdr------------------- 945  Desulfocap...
Q6AL39           919 -----------------EVCSGN---NLKQMLTgtpnkgaiSQE---QFSLKKDAQIIVdkwkg---------------- 959  Desulfotal...
Q2LSZ0           957 -----------------EKAAGRDLSLLQQTLT--------------AEQDSRAFEQARrk------------------- 986  Syntrophus...
WP_015948622    1035 -----------------VVRFGRDVRELAQSMG--------------EVKDLGHLEKLRkq------------------- 1064 Desulfatib...
WP_012174408     983 -----------------EIEVSRNRDILRQSFD--------------QGLPADSLAPLKrq------------------- 1012 Desulfosud...
WP_015905566    1007 -----------------EVAASRENDLLDKYAKghg---------snDLLFEDAKRRL---------------------- 1038 Desulforap...
WP_277002314    1011 -----------------EIKSLRDLSKLGTFAT--------QRPaqkTNAFERTKKAF---------------------- 1043 Desulfobac...

WP_012876860    1259 anpsvvepvettgrrvvstgsttggggsttggggsttgrpggsttgggrgvvaERLGLATWPDGlp----dgRLPDVVST 1334 Xylanimona...
WP_013042930     999 ------------------------------------------------ataqyEKENLSRWSFG--------DLPESIDL 1022 Coraliomar...
jgi:DaAHT2_0729 1000 -----------------------------------------------------------RWQRQnisgaelpEIPQRLPM 1020
WP_015405382     946 ----------------------------------------------------wQDTLFQKWDFD--------GLKRNIPL 965  Desulfocap...
Q6AL39           960 -------------------------------------------------------wegdSWAFD--------QLPASIPL 976  Desulfotal...
Q2LSZ0           987 ----------------------------------------------------wEKSDLTAWDFG--------EIPESIDL 1006 Syntrophus...
WP_015948622    1065 ----------------------------------------------------wEKTGIKSWDFG--------DLPSSIPV 1084 Desulfatib...
WP_012174408    1013 ----------------------------------------------------wEKTGCRTWEFG--------DLPEEIVA 1032 Desulfosud...
WP_015905566    1039 -----------------------------------------------------ERTGVTSWDFG--------DISSPVLL 1057 Desulforap...
WP_277002314    1044 -----------------------------------------------------EKTGLREWNFP--------DIEQEIQL 1062 Desulfobac...

WP_012876860    1335 DLgGGVVVR--GYPALV----EEPGpkqeptVALRILADALEQPATHARGVRRLLLAENRLTAGRVTSRWSG-------- 1400 Xylanimona...
WP_013042930    1023 SDaAGLPLN--AYPALVe---SKGQ------VHLRLKQDLATALAATRNGWPALGEAVLARDLAWIRKDLKD-------- 1083 Coraliomar...
jgi:DaAHT2_0729 1021 TG-PDGQLIgyLFPGLQe--dDRGR------VNLHLFTAEKPAHLATCQGLLRLFCREFTARLKGLRKDLTF-------- 1083
WP_015405382     966 FT-QSNEIAgyLYPALHve-rNRGG------VTISFESNRKTAATLNLSGSLFLYQLKFKDEFKSLKKYCHTalsapssq 1037 Desulfocap...
Q6AL39           977 YN-KQGSISgfLFTVLDpi-eQRSK------VQVNFTRNKQEALQRNQKGLSYLYQLQFKGQLKPLRKSCSSalsapssl 1048 Desulfotal...
Q2LSZ0          1007 HA-NG-SFKgcAWPALTp---GDGC------VHLRLYKTREEAACVHREGIAALYGLYFTRELKELKKAL---------- 1065 Syntrophus...
WP_015948622    1085 K--KG------APPAYVclcpGDDC------VDLKIVEDKVKAQATHKKGVAALCTLECAKDIKHIKKYL---------- 1140 Desulfatib...
WP_012174408    1033 DA-GKRHIR--LFPGLVd---RTGH------VDLRLFESRSKALAAHVQGVKRLLLLALSREVRFLGRDV---------- 1090 Desulfosud...
WP_015905566    1058 G--QGQELSynVYYGLQs--eEQG-------VGLRLFKSHAEARRSHVAGVEKLSTICFEADFKALKKDV---------- 1116 Desulforap...
WP_277002314    1063 D--EGNGTRrkAFPGLCcg-pDSDS------VTLTLFKTREMALESHAKGVCRLFEIMFPDDIKALKKDI---------- 1123 Desulfobac...

WP_012876860    1401 --TQAL-TLAA-SPY-----RNTNLL------AE---DLQLATVMALTspaadlapgtpaGPHAvqiRDAESYNAAKAHV 1462 Xylanimona...
WP_013042930    1084 --LKQLgTLLL--PL-----GNAKQV------EE---PAWLHIRRHLF------------RTGIllpLKQSRFDKVLQRA 1133 Coraliomar...
jgi:DaAHT2_0729 1084 --PRQHwRLAH---------G-VASL------EElnrAIEQFVLREIF------------ATGSgelIGAAEFQARVEKL 1133
WP_015405382    1038 wlIALF--------------GNKTKA------ND---ALLEFVMRSLF------------TQKLdtiPDKSTYEAEVEKV 1082 Desulfocap...
Q6AL39          1049 wlVKNY--------------SDRKEA------SD---HLLQFILQGIF------------DLSEatlPGKESFAKVIGEV 1093 Desulfotal...
Q2LSZ0          1066 -------KLTEpLKTw------AESFigvrnmES---RLLEKVKKDLF---------------AvdvRTAEDFEAHARKI 1114 Syntrophus...
WP_015948622    1141 -------ALKGnAAKhaayfGGTKQM------EQ---VLFDTLLERTL---------------EkelHTEEEFREHVKTR 1189 Desulfatib...
WP_012174408    1091 -------ALSKqAALkavllGGAKSL------EQ---RMQQKVADNLL---------------AvsiRTAAEFEALAIEV 1139 Desulfosud...
WP_015905566    1117 ---KKWtLLRPrTSKf----GGWERF------QN---ALVSCVFRELF---------------SrdvRTPKAFLELADKH 1165 Desulforap...
WP_277002314    1124 ---NRTeGLRRiAPYf----NDKPTF------AR---MAYNAMAKAFF---------------QkeiFTQKAFDDHVQAL 1172 Desulfobac...

WP_012876860    1463 -RTHLEDETYRVAGHVVAALTAWRTLESEVrktssl---------------allntlQDIRE---HAATLIHDGFVSATP 1523 Xylanimona...
WP_013042930    1134 -DSERRGIVNQLLDQLRALLEARQAIELLLqqkqtk----------------qaisyPGLRA---QMEQLAPSNLLERYE 1193 Coraliomar...
jgi:DaAHT2_0729 1134 rRDGFYQEARRLYELILLVLQERWETLQAInrlvppaaggqsrvgsaaaaglpaeliAELQQ---ELAELLPPDFLEHHD 1210
WP_015405382    1083 qQLGLYRRGQEICDEMFQILRKRKEVSSHInhyaglsrk---------shsyneaqfKEYET---LLEDILPADFLTTQS 1150 Desulfocap...
Q6AL39          1094 qKMGLLQRGNLICQDIAEIFRLRRETAELLekvflt----------------rknanKEKETfslLIEEILPKTFLQEKE 1157 Desulfotal...
Q2LSZ0          1115 -AGKILISGQEGIRTVEPLLKAWFEIAGDFrnleivnrg----------nsgarefiLQLRR---EMEGLLPADFLCRFD 1180 Syntrophus...
WP_015948622    1190 -IPALVAQGEKLVESTSRIMEAFHKTSFRIseleaqcrn----------nkfglaflKNLRT---AMTQLLPPNFPNLYD 1255 Desulfatib...
WP_012174408    1140 -PGRLYERAHQLRTAVETVVGAYHDARRQIqtlvasqra----------ggdtalvlKTIEA---DLATLVPETFVTIYH 1205 Desulfosud...
WP_015905566    1166 -LPLVYRHGEELMKTMVTLFDEHDRTLTLLknlflksgn----------rptvlamaQTLEK---DLAALLPELFPSLYD 1231 Desulforap...
WP_277002314    1173 -RPKLYTLGRQAMEEILTVGREYATCFDLLqslslasre----------rplifealTAIFN---ELKNLCPANFLELYD 1238 Desulfobac...

WP_012876860    1524 PRRLPHLVRYLRAASYRLEKAQASPHRDAELAWRIHDVEEAYAKAraa-yaaGPADaaRAAeLAEVRWLIEELRVSLFAQ 1602 Xylanimona...
WP_013042930    1194 FNELPHLTRFLRACMRRAERARTNIQSDIEKSQRVAPFEKHLIALnklaqsdA-----HRAqTKAYQMLLEEFKVSVFAQ 1268 Coraliomar...
jgi:DaAHT2_0729 1211 AASLARLPRYLKALQIRTQRALSDPAKDAAKAARLAAFKQRLQKYpdaselsAG----KRSvLAEYRLMLAEYKISLFAQ 1286
WP_015405382    1151 AEDLAGCDRFFQALKIRIERAYANPAKDMTKSRQLESYVNRQKQIprditglPFE---CRKaLSLYSAMVAEFRVTIFAP 1227 Desulfocap...
Q6AL39          1158 ID-LNSCRRQFRSLQVRLERFSANPVKDGQKNALLAPHLKNIEVAektreklSDE---ACQlLDQYKKMVQEFRISVFSP 1233 Desulfotal...
Q2LSZ0          1181 AGRLSHIPRYLKALKIRAERGLLNPEKDRRRERELLPFVTRHNELvqnmtsgVSDE--KQQaLADLSLMIEEFKVSLFAQ 1258 Syntrophus...
WP_015948622    1256 DARLAHMPRYLQAVTIRAERGLLDLDKDKAKAAQVREFEDHLRRLakelgikTTPE--KRQaVEDFFWMIEEFKVSVFAQ 1333 Desulfatib...
WP_012174408    1206 IADLERLPRYMQAAVIRARRAVENLAGDRQKAEKVAWSCAVLDRLvaellpdTSDE--KRRaVEDFFWMVEEYKVSVFAQ 1283 Desulfosud...
WP_015905566    1232 FTRIKKLERYVAAIRIRAERGAVEPVKDSVKAGLVAEHTLKLNNLvatlskeSSRE--KVEaVEAFYWMIEEYKVSVFAQ 1309 Desulforap...
WP_277002314    1239 LNRIALLPKNLECLSIRARRWVDNPAKEAQKKQLVAPYEQKLAHLissldpgSSKE--KSNaVEAFFWMLEEYKISVYAQ 1316 Desulfobac...

WP_012876860    1603 QLGTDGTVSEKRIRKTL 1619 Xylanimonas cellulosilytica
WP_013042930    1269 ELGTAQKVSEKRLEKLY 1285 Coraliomargarita akajimensis
jgi:DaAHT2_0729 1287 EIKTIFPVSPQRLEEKW 1303
WP_015405382    1228 ELKGGMQVSEKKLKLQW 1244 Desulfocapsa sulfexigens
Q6AL39          1234 EIKTQMPVSDKKLLQHW 1250 Desulfotalea psychrophila
Q2LSZ0          1259 ELKTAFPVSARRLEEKL 1275 Syntrophus aciditrophicus SB
WP_015948622    1334 ELKTPMPISPKRLQKRL 1350 Desulfatibacillum aliphaticivorans
WP_012174408    1284 ELKTAFPVSKKRLEENL 1300 Desulfosudis oleivorans
WP_015905566    1310 ELGTLVKISPKRLNTMW 1326 Desulforapulum autotrophicum
WP_277002314    1317 ELKTRFKISAKRLDEAL 1333 Desulfobacter postgatei
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