Conserved Protein Domain Family
SET_assoc
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pfam11767: SET_assoc (This model is not part of the current CDD release)
Histone lysine methyltransferase SET associated
SET domains are protein lysine methyltransferase enzymes. SET domains appear to be protein-protein interaction domains. A subset of SET domains have been called PR domains. The SET domain consists of two regions known as N-SET and SET-C. SET-C forms an unusual and conserved knot-like structure of probably functional importance. Additionally to SET-N and SET-C, an insert region (SET-I) and flanking regions of high structural variability form part of the overall structure. This domain is found in fungi associated with SET and N-SET domains.
Links
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Statistics
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PSSM-Id: 492091
Aligned: 58 rows
Threshold Bit Score: 65.2238
Created: 21-Aug-2024
Updated: 4-Dec-2024
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_003715029  472 FVAHKSVPVSPLTVPHMKKRLRGFTMDDILiIEKYGYYLIFADSSygrdQAERCYKCTNHSRFFDYDMIM 541 
Q6CIT4        355 FVPAKITFYHRFNAADFRYQLRKYNWAKII-DHYTGVYIVFHDLE----NAKACLEYESGALVINSHRTH 419  Kluyveromyces lactis NR...
XP_003675158  417 FVSRVFMALHGFRTEDFKYKLRRYRYSKFL-DHITGLYIVFGDLL----ECKKCFELESGKMTLVSRSRR 481 
XP_003668713  429 FVPKTFLFFHGFRIEDFKYKLRRYRYSRVL-NHATGIYIVFNDLK----ECQNCRNIESGKLTLLSRklh 493 
Q6FKB1        458 YISRRFISVMGLRLIDFKSKLKAYKCSRFL-EHATGFYIIFNNLE----HAKLCMDAESGKLTMASRrkr 522  Nakaseomyces glabratus ...
P38827        422 HVSKIFVAKHRFCVEDFKYKLRGYRCAKFI-DHPTGIYIIFNDIA----HAQTCSNAESGNLTIMSRsrr 486  Saccharomyces cerevisia...
XP_001646446  405 FVPKSFTSIHSFRVEDFKLKLRKYRWARIL-DHQAGIYIVFNDLV----HARSCMNAESGIMTLISRSRN 469 
XP_003679850  367 cISKFFANNHGFRVEDFKAMLRRYAWTRII-DHPAGIFAVFNDEE----SARTCMNNESGRMTMISRtkr 431 
XP_003957802  418 FVSKVFTSLHGFRVEDFRYKLRNYSYARFV-DHISGIYIVFNDIE----EAKRCIHNESSKLTLISRSRR 482 
Q4PB36        780 YVHIPRPKNCDIDVTSVEAQLRSTAPIWVR-EGQKGFYAAFHTSK----EANQCKVVNETLTIGGYTLQV 844  Ustilago maydis 521
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