Conserved Protein Domain Family
CAP59_mtransfer

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pfam11735: CAP59_mtransfer 
Cryptococcal mannosyltransferase 1
The capsule of pathogenic fungi is a complex polysaccharide whose formation is determined by a number of enzymes including, most importantly, alpha-1,3-mannosyltransferase 1, EC:2.4.1.-.
Statistics
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PSSM-Id: 403053
View PSSM: pfam11735
Aligned: 188 rows
Threshold Bit Score: 180.043
Threshold Setting Gi: 58259053
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
CAM45646               288 HFYIALNLWKNE-EVLPDLTEALIVFLEedvkpFF--DlatSVVVAIYSNISPDRTSELIAtLLIPRLHAAG-VRNVYat 363  Leis...
WGS:AAWC:PGTG_11650.3  179 KVMIALNLHSSQ-DVLPAIANAILNSLR-----YLgiE---NVFVSVYENGSWDHTPEGLG-HLGAVLTGLG-VRHHIrs 247  Pucc...
XP_003047949            63 dyIFAVRVVNNLdQL-PTLLGAVLNAMY-----YLgpY---RCALTVISSGWRPHLDDVLE-ELHLGLNHIG-AVYNYts 131  [Nec...
ERT03378               113 KYYFAIDLRDTV-PLLPRLLGSVVETIK-----FLgpA---SCALSIVEGNSHDGTYDILQ-AIRASFNDLD-TTYFLrs 181  Spor...
EPE05347               116 KYFFAIDLREAL-PVLPRLLGSVVETIR-----FLgpS---NCALSVVEGNSNDGTYDVLH-ALRPKLDSLA-TTYYLrs 184  Ophi...
EFX06014               123 iYFFAIDLREVV-GLLPRLLGSVVEVVR-----FLgpE---KCALSIVEGNSRDGTLEVLE-ALRPSLDALA-TTYYLqs 191  Gros...
XP_008078737           157 KYYFAINLHDSI-QIIPRLLGSVVETMR-----FLgfD---RCTLSIIEGRSVDGTYEVLK-SLAPALGKLG-VTYHFns 225  Glar...
jgi:THITE_2111903       97 RYFFALNLRNCL-PLLPQLLGSILEVIR-----FLgpE---HCALSIVEGNSPDGTAEVLA-ALEPELIRLGiRTYFTln 166  Thie...
XP_007849496           156 KYFFAINLYNSF-DIIPDLFATLFRISA-----ILgpQ---NIYVSIYENGSTDQTKALLR-IFDALTKSVG-LRVTIrt 224  Moni...
EKC98868                15 KYFIAINLYNSF-DVIPDLFSTLFKTAA-----VLgyH---NVFVSIYENGSKDQTKALLR-LFDALARTVG-LRVTIrq 83   Tric...
CAM45646               364 tegtclgyvERQpFHERIEWMACIRNKALEPLYE---------KGMnVFggsqQQqqeqqadvngdadglvVLFFNDILF 434  Leis...
WGS:AAWC:PGTG_11650.3  248 are-----etiwtGVDRIKLLSEYRNMALSSF-----------ENAdRAlhgiSE----------------LVFINDVFL 295  Pucc...
XP_003047949           132 fay--------------gpraYKHRNQAIGAVrharke---------------------------vsedatIVFLDDVDI 170  [Nec...
ERT03378               182 s-----avdPk--EGDRIAKLAELRNLALQPLLDgnvp-----------gadqDt---------------tVVFLNDVAA 228  Spor...
EPE05347               185 s-----tinPq--QGNRIAKLAELRNIAVQPLREepar------------ytaDt---------------tVIFLNDVAP 230  Ophi...
EFX06014               192 s-----dvdPl--KGDRITRLAELRDMALQPLRDeggqry--------------------------sakttVIFLNDVAA 238  Gros...
XP_008078737           226 s-----dvnPe--VGNRIGNLAALRNDALEPLRAspt--------------yeNa---------------sVIFLNDVAI 269  Glar...
jgi:THITE_2111903      167 n-----qidPLAeGSDRFSSLATLRNLAVAPLLaafsnpptitTTAaANa--------------------sVLFINDVAI 221  Thie...
XP_007849496           225 smrt------rgafnhRIEYLAEVRNAAFLPLHElr------dAEGeIF----DT----------------IVFMNDILP 272  Moni...
EKC98868                84 smrt------rgafnhRIEYLAEVRNAAMTPLHElr------eNEGeVF----DT----------------IVFMNDILP 131  Tric...
CAM45646               435 HPQDITALLESraeArmaatTrphgwlssvmktkhesaevadagiggkgnlekrhvsttsplpsgatsttppttFDMACG 514  Leis...
WGS:AAWC:PGTG_11650.3  296 CAQDILELIWErnfQ-----K-----------------------------------------------------ADASCG 317  Pucc...
XP_003047949           171 CSEDILELILQrenL-----G-----------------------------------------------------ADMTCG 192  [Nec...
ERT03378               229 CTEDILELVHQrrrL-----G-----------------------------------------------------ADMTCG 250  Spor...
EPE05347               231 CSEDILELIYQrhaQ-----N-----------------------------------------------------ADVVCP 252  Ophi...
EFX06014               239 CPEDILELVHQrqvL-----G-----------------------------------------------------ADMVCG 260  Gros...
XP_008078737           270 CMEDILELVHQritL-----E-----------------------------------------------------ADMVCG 291  Glar...
jgi:THITE_2111903      222 CADDLLELAHQrarQ-----G-----------------------------------------------------ADMACA 243  Thie...
XP_007849496           273 CVDDILELIYQsrlN-----N-----------------------------------------------------AGITCA 294  Moni...
EKC98868               132 CVDDLLELIWQsrrQ-----N-----------------------------------------------------AGITCA 153  Tric...
CAM45646               515 MDFYF---------------------------TFYDTWITRDRLGKPF------------------KPQMPYSDD----R 545  Leis...
WGS:AAWC:PGTG_11650.3  318 TDWREsktildeygwtsksngpsntdnpsksvVLYDSWVARSLTGKT--------------------------------L 365  Pucc...
XP_003047949           193 MQWAPnksn--------------------gipLLKNDGTCRDMQGERFghvppe-------kwtegTDVKEYFWKs---S 242  [Nec...
ERT03378               251 LDWVyvg----------------------rdpTFYDVWVARGMNGDSFfeippdgnw-nsawnlfwNN-----------D 296  Spor...
EPE05347               253 LDYTyvg----------------------rdpTFYDVWIARGMNGDSFfeippdgnw-nsawnlfwND-----------D 298  Ophi...
EFX06014               261 LDWVyvg----------------------rdpTFYDVWVARGMGGDSFfeippdgnw-nsawnlfwND-----------D 306  Gros...
XP_008078737           292 MDWKnlw----------------------kdpTFYDVWIARTMTGDSFfevgedgnw-dsawnlfwSD-----------D 337  Glar...
jgi:THITE_2111903      244 MDWTgatddddd------------dddaqpgpAFYDVYIARAINGDLFfdvppatvswdraadlfwNE-----------P 300  Thie...
XP_007849496           295 ADYMYhsei--------------------qspVFYDNWVARDINGTALe----------------nAP----FEMilhhP 334  Moni...
EKC98868               154 ADYMYhdei--------------------gapVFYDNWVARDLNGTALe----------------nAP----FEQvfhhP 193  Tric...
CAM45646               546 ATQEAFYRifnhepsg-----------gyapetsAIPVKCCWNGLAAIRGRFFlPPtpqHR-LEFPAQ-------DAAET 606  Leis...
WGS:AAWC:PGTG_11650.3  366 RPRLDFLTeyrdgysvifdhedtklyqnrfqnalAVPVYSCWNGIVALSPRPF-RAp--TG-LKFRAAdrkidecPSSEC 441  Pucc...
XP_003047949           243 KDQARFNEk------------------------rPFQVFSCWGGAAAFTASTF-TR---LE-QIFRLPikg-aecTQPDT 292  [Nec...
ERT03378               297 AARASLAAh------------------------rPFQVFSCWNGAAVFAAKPL-LDa-aSR-IRFRGPrdg--ecSQGEP 347  Spor...
EPE05347               299 DAKSQLFSr------------------------iPFQVFACWNGAAVFTAKPF-VE---KV-ISFRAPydg--ecSQGEP 347  Ophi...
EFX06014               307 DGRSGYFEh------------------------hPFQVFSCWNGGAVFTAAPI-VD---GT-IRFRGPseg--ecKQGEP 355  Gros...
XP_008078737           338 KTQQRFQDh------------------------lPFQVFSCWNGGAVFGARPF-FK---TA-IEFRAPreg--ecFNGEP 386  Glar...
jgi:THITE_2111903      301 IARARLERh------------------------aPFQVFACWNGAVAFTARPL-VE---GK-VAFRGAradkgecWQGEP 351  Thie...
XP_007849496           335 ESSARFQAh------------------------lPIQVQSCWNGIAVLDPAPF-YEp-pHVrVRFRMAritegecSASEC 388  Moni...
EKC98868               194 ESNSRFQRh------------------------lPIQVQSCWNGVAILDPAPF-YEq--PH-TRFRMAdllkkecSASEC 245  Tric...
CAM45646               607 TVR 609  Leishmania braziliensis MHOM/BR/75/M2904
WGS:AAWC:PGTG_11650.3  442 QLL 444  Puccinia graminis f. sp. tritici CRL 75-36-700-3
XP_003047949           293 RLF 295  [Nectria] haematococca mpVI 77-13-4
ERT03378               348 ELF 350  Sporothrix schenckii ATCC 58251
EPE05347               348 QLF 350  Ophiostoma piceae UAMH 11346
EFX06014               356 QLF 358  Grosmannia clavigera kw1407
XP_008078737           387 AIF 389  Glarea lozoyensis ATCC 20868
jgi:THITE_2111903      352 QAF 354  Thielavia terrestris NRRL 8126
XP_007849496           389 SLI 391  Moniliophthora roreri MCA 2997
EKC98868               246 SLI 248  Trichosporon asahii var. asahii CBS 8904
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