Conserved Protein Domain Family
Inovirus_Gp2

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pfam11726: Inovirus_Gp2 
Inovirus Gp2
Isoform G2P plays an essential role in viral DNA replication; it binds to the origin of replication and cleaves the dsDNA replicative form I (RFI) and becomes covalently bound to it via phosphotyrosine bond, generating the dsDNA replicative form II (RFII).
Statistics
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PSSM-Id: 403046
View PSSM: pfam11726
Aligned: 20 rows
Threshold Bit Score: 116.298
Threshold Setting Gi: 295797474
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P52125          17 RIKQVIDDSLNEHLNSMILRVDLHDPIDTENM--DNpffqprvdsGAISRFTSALKAKL------------KHDKHIKTQ 82  Escherichia c...
WP_012368757    13 QIDRTVRKSLLTNNRVTAIRVDLRFPSSTTCYheDS---------TVITRFIESLKAKI------------GADLRRKNK 71  Proteus mirab...
Q47ZW5          43 vhEKVLMKALSHHKRTSAFRFELKFPRNKQYI--VN---------HAISKFFDSLRVRI------------KSDIANKNK 99  Colwellia psy...
Q4FTE5          33 SLNKYMSYFLEKYARVLIVRVDVKI----------KvefahlvdiETFNGFVNQLMETI------------QRDREIEKK 90  Psychrobacter...
jgi:Alvin_3272 175 gslNYINYLFERYARLLVVRVDLSF------------------------LTPSQCHDRDwtpvtfedalayRERFTRSWK 230 Allochromatiu...
Q7MP50          47 SMVDVFEQALSQFDIALATRLDLFLPEDHQDT--DL---------SILNDYFNLLKEKL------------DTD------ 97  Vibrio vulnif...
Q9KUL9          35 TMDKVFDQALTQYQRTLAMRLDLYLPKDHQDT--DL---------SILNDYFDILKEKI------------DAD------ 85  Vibrio cholerae
Q9KUM0          40 EIDRVLTEALNQYPRIFAVHINLNLPSDFGEDy-----------lTVFAHFFRILESAT-------------NELCKDKY 95  Vibrio cholerae
Q9KUM1          32 gIESVLENALEQYARLFIVRVDLNLPTDFRGD--DS---------AVMTRFFRSLKSQV-------------AAYRRRSA 87  Vibrio cholerae
jgi:Tola_2275   33 RIIETVQKSLRYYSRVRAFRIDLRFANDYMDGdvDTpshfqqadpKAITRFFESLKSQL--------------KVYRKNK 98  Tolumonas aue...
P52125          83 RkdWPDS------RHSTLRYAWVREYTK-NRKRHYHLILCFNQDAYYHLGDYD-LNRNTLRTMITTAWYSALGIPIDSSG 154 Escherichia c...
WP_012368757    72 V--WARN------YSCPLSYVWVREFGEiSSRKHYHLLLLVNKDVYWGLGDYT-KTEGTLYALIQQAWCSAIGVNYSTER 142 Proteus mirab...
Q47ZW5         100 R--LDKK------YECKLSYVWVCEYST-SINWHFHVVIFLNRDVYNCFGRLK-ANEGNMYSRIRAAWASAIGVSFDAAL 169 Colwellia psy...
Q4FTE5          91 RkaGKVAdkdkgsFEDLRGYAWAIEQGVdNGGLHCHLVLIYNGDKR--------QHDWFLGEAVGKKWVEIT-------- 154 Psychrobacter...
jgi:Alvin_3272 231 R---EPL------FEHLVGYVWKIEHGA-LKGFHTHWLFFFDGSKV--------REDMTLGHLIGEHWKVIV-------- 284 Allochromatiu...
Q7MP50          98 ----------------SLFYVWRKREDK-VPSHNYRVMLFSDYSQHFGPAICW-DKRNELVGHLKTAWQEAIEKHYSGEA 159 Vibrio vulnif...
Q9KUL9          86 ----------------SLPYVWRKRADK-TPSHNYRVMLFLDDSQYFGPAICW-DKGNQLVDHLKTAWKEAIEKHYKGKE 147 Vibrio cholerae
Q9KUM0          96 TdrTYRY------QQTVIRYIWAKESK--STSKHHHLILLFDRDLFQNLGTGReGWGRFLYKKVRKTWDRVVEAYYRQPC 167 Vibrio cholerae
Q9KUM1          88 RlnRKPY------RETTIRYVWAKECDT-STSSHYHVALIFDRNIFRSLGDFG-EYQQSLANRIRNAWKRSVEAMYSGKE 159 Vibrio cholerae
jgi:Tola_2275   99 N---IMV------SRDDFKYIWTREKDE-SFHHHYHLVLLFDKDVYYHLGDCSpDNSSGIAAMIQKAWCSALRVSFPEYA 168 Tolumonas aue...
P52125         155 -KLVNYPPNGKYLLN-RKRDNFEQTY-------------------SDLMNRVDYMTK---VRTKIVGDG--DRNFGCS 206 Escherichia col...
WP_012368757   143 -YLVHIPDNAVTWLD-NNNANNESTI-------------------FELNQRCRYLAK---EHTKYYGDG--ERSFGCS 194 Proteus mirabilis
Q47ZW5         170 -GLVHLPDNDVYDVN-TNADNYEQQL-------------------EDILYRLSYFAK---VQTKPYGQGgdNRFFGYS 223 Colwellia psych...
Q4FTE5         155 -------GGLGWHNN-GNTTERKRHYerqgtlgigmihgnnplevKNAIYAALYLTRpdkYEQRLKAWTpsMRSFGRG 224 Psychrobacter a...
jgi:Alvin_3272 285 -------GSHATYWN-CNV--YKTQYrhlgigqi---dhadqtkrQALQRVVQYLCKvddFISLKHTGR--RRAFGRg 347 Allochromatium ...
Q7MP50         160 rSLVFLNDRGNYGVGtRCRSKDVNIK-------------------NTVFHRMSSLAEaweEK---------RYCFGSS 209 Vibrio vulnific...
Q9KUL9         148 rSIILFNNRGNDGLGtRCKSKDTNIK-------------------RCVFHRLSSFAEawkEE---------RYCFGSS 197 Vibrio cholerae
Q9KUM0         168 sGLAYSPTNEGFELF-SDTESFPLQL-------------------NEFFYRISRLAKptaNRNAHP-----NKSFGCS 220 Vibrio cholerae
Q9KUM1         160 kPAIHFSKQGQYHLL-RNSEEFGEVF-------------------QSVFYRLSYLAK---RRTKHFGKR--MNNFGHS 212 Vibrio cholerae
jgi:Tola_2275  169 -TLVHFPDNCAYNLEgKNATLQDEKF-------------------IWALERFLYLSK---VDTKTTDDG--FRNFGCS 221 Tolumonas auens...
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