Conserved Protein Domain Family
Toxin_YhaV
?
pfam11663: Toxin_YhaV 
Toxin with endonuclease activity, of toxin-antitoxin system
YhaV causes reversible bacteriostasis and is part of a toxin-antitoxin system in Escherichia coli along with PrlF. The toxicity of YhaV is counteracted by PrlF by the formation of a tight complex which binds to the promoter of the prlF-yhaV operon. In vitro, YhaV also has endonuclease activity.
Links
?
Statistics
?
PSSM-Id: 492012
Aligned: 26 rows
Threshold Bit Score: 186.715
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
?
Aligned Rows:
Download Cn3D
PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
Q89TU0        13 VYAHPLFLDQFETMIAAVEKARKKDP-KGYKKKRAAKLLSAVLKVAFDDIPSDPTRDVYRQGGTLGD-EYKHWFRAKLLQ 90  Bradyrhizobium ...
P64594        12 LYAHPCFQETYDALVAEVETLKGKDP-ENYQRKAATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSgKNKDWSRVKFGA 90  Escherichia col...
WP_015209563   8 LKIHPAFGEQYQKLINQVEQLKEKNP-EEYQMHPATKLLNNITELIFKRIPEDPTAPEFRQGKTLGT-ERKHWFRAKFNR 85  Cylindrospermum...
1_pfamImport   1 LLFHDCVIEQLQKLHAAARRAQENDP-NGFESNANVKLFRALSQLMLDVVPSDPARDEYRQGNTLGP-AHRHWRRAKIGR 78 
WP_015220445  11 IYFHPLFYQQWLELVNRVKYLKQRSApENFVTHPDVKLLKALDQGIKDKIPKDPFASYFALKKPLQ--KYSRLKKMGLPS 88  Cyanobacterium ...
WP_015192019  11 IFFHPLFNAPWISLVAKVKQLKTKLEpKDFVTHPDTKLLKAIDLGIKDKIPSNPFASYFALQKPLH--KYGRLKKMGLPN 88  Stanieria cyano...
WP_015079922  15 IFFDPLFNTQWIELRDKVKKLKDELPkEEFIKHPDAKLLKALNIGIKEKITQDPFASYFILQKPLQ--KYGRLKKMGLPE 92  Anabaena sp. 90
WP_012167212   9 yfLKRLFGQQRLALRTEVKRLKATLPpEDYVRHPQVKLYAATMQAIKAKIPADPFASHFALTGPLK--KFGRVKKMGIPN 86  Acaryochloris m...
WP_015197878  12 YFHPQLFGTQYQELFDRVSELRKKLPeSEFKTHATVKLFAAITIAIETKIPSDPLASHFALTGALK--RYGRVKKMGLPE 89  Calothrix sp. P...
WP_015158542  12 YFHRQLFGEQRRQLRERVKQLKAELPeADYLTHPDVKLLAAVMVGIKEKIVLDPLATQFALTGPLR--RYGRMKGMGLPQ 89  Chamaesiphon mi...

Q89TU0        91 -QFRLFFRYQqsADAKIIVLAWVNDDSTLRAYESANDAYAVFRKMLDRGNPPDSWNELVAAAS 152 Bradyrhizobium japonicum
P64594        91 gRYRLFFRYS--EKEKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWETLTRETE 151 Escherichia coli K-12
WP_015209563  86 -RFRLFFRYS--TAKKIIIYAWVNDEFSLRKEGSKTDPYQIFTKMLENGNPPDSWDELLNVSN 145 Cylindrospermum stagnale
1_pfamImport  79 -RFRLFFRYD--SKAKIIVYAWVNDEQTLRSSGSKSDPYAVFEKMLGRGNPPDDWNALVLASK 138
WP_015220445  89 -RYRLFFRVFk--EANTIIILWLG---FPRKERDKKDCYKVFSKMVINGNFPEDIASFLDLAN 145 Cyanobacterium aponinum
WP_015192019  89 -HYRLFFRAF--KEKKVIIILWLG---FPRKEGDQKDCYQVFSKKILKGEFPNSLDDFLREYQ 145 Stanieria cyanosphaera
WP_015079922  93 -RYRLFFRVF--KEQKIIIILWLG---FPRKEGDKKDCYQVFTKKVENGDFPENVDQFMIeym 149 Anabaena sp. 90
WP_012167212  87 -RYRLFFRAFkvPESQSIFVLWLG---YPRKEGDKKDCYRAFRKMVERGDFPDSLDDLMVESE 145 Acaryochloris marina
WP_015197878  90 -RYRLFFRAFdtPKLKSIVILWLG---FPRKEGAKDDCYQVFTKMVARGTFPDSLDELIKEpg 148 Calothrix sp. PCC 6303
WP_015158542  90 -RYRLFFRAFtsEERQVLIVLWLG---YPRKAGDKQDCYEVFTKMVGNGDFPDNLPELLMATd 148 Chamaesiphon minutus
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap