Conserved Protein Domain Family
Med16

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pfam11635: Med16 
Mediator complex subunit 16
Mediator is a large complex of up to 33 proteins that is conserved from plants through fungi to humans - the number and representation of individual subunits varying with species. It is arranged into four different sections, a core, a head, a tail and a kinase-activity part, and the number of subunits within each of these is what varies with species. Overall, Mediator regulates the transcriptional activity of RNA polymerase II but it would appear that each of the four different sections has a slightly different function. Med16 is one of the subunits of the Tail portion of the Mediator complex and is required for lipopolysaccharide gene-expression. Several members including the human protein MED16 have one or more WD40 domains on them, pfam00400.
Statistics
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PSSM-Id: 371639
View PSSM: pfam11635
Aligned: 15 rows
Threshold Bit Score: 522.016
Threshold Setting Gi: 122067238
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
A3LY88        147 QDPALPVNPGAAIVSFSWLNIEKVQIINKPAALVTLEnqns-------------------snspFVYTYGVNQFQPHGVT 207  Scheffersomyc...
Q59PP6        190 PDINVAVNPGASIVAFKWLNIEKPQIVNKAATRLAENpttts-----------------snsssSIYGYGINQYQPYGVC 252  Candida albic...
EDK46979      128 QDMSSPVNPEASIVAFKWLNIEKPQILNKPAALVAPQdhqlassssaaaaaagssattnnstssSMYAYGVNQYAPHGLS 207  Lodderomyces ...
Q75E72        153 ERKHTKKEYYSTILDFQWIGNQKPSVAQVAAQRDRTN---------------------------NIFKNQMHQCPPYGVF 205  Eremothecium ...
Q08D69        108 QSLVGSEVDGDPIVALSWLHNG-VKLALHVEKSGVSS---------------------------FGEKFSRVKFSPSLTL 159  tropical claw...
Q16K67        114 KSVYSVKFPGENIIAAAFFHNG-RKLNLQTDKKDQYL---------------------------YLEKFQKVKFAASVRQ 165  yellow fever ...
XP_001541319  133 QASMDADDDWSQPVGLMWLNLNRPLFGFHKATRANDR-----------------------------WNYPAYRRRPLGPL 183  Histoplasma c...
Q0D1E0        140 QGAFDPDDDGAQIVGMMWLNVHRSVQAFSQANKRQGR-----------------------------WNYSSFRRRPIGPF 190  Aspergillus t...
A1CQ63        142 QATSDPDDDGAQIVGMMWLNVNRVVHAFHQAAKVQGR-----------------------------WAYSPFRRRPIGPF 192  Aspergillus c...
CAK45284      140 RQPAFSPDDGSQIVGMMWLNTQRSVHAFYQAAKVQGR-----------------------------WAYSPFRRRPIGPF 190  Aspergillus n...
A3LY88        208 HPISTKQACVALRQNGQFT-LYFQGEHKVEYHKTS--VALSDDIVI------------------ITKASIGFTNDKQ-IV 265  Scheffersomyc...
Q59PP6        253 HPIPTKQACVALRKNGQFI-LFYQGEHKVEYHKIC--CNLTDNISI------------------IEKASIGFNNDKQ-II 310  Candida albic...
EDK46979      208 HPIATKQACVALRRSGAFM-LYYQGEHKVEYHKTM--VNLNGLQPLqlqlqllplmlhahipmmIDKAAIGFTNDKE-II 283  Lodderomyces ...
Q75E72        206 HPASIKSACIAIRRNGYID-LWYQFSNTLDFKKIS--LQLSKDkes----------------ewLQYAQIAHTDKEQcFL 266  Eremothecium ...
Q08D69        160 FGGKPMEGWIAVTVSGLVT---------VSLLKPN--GQVLTATESlcrl-----------rcrVALADIAFTGGGNiVV 217  tropical claw...
Q16K67        166 FGGVPVEGVLIVSATGMLGaFVIPPESNANIQKLSepIKLVPVTESlavt-----------rnyYTTADICYGKNGYfRV 234  yellow fever ...
XP_001541319  184 HPA-NKPGLVVVTKSGHIK-LIYQ-NPDSRWAEIS--TELKAVGyld---------------glLTHAALAPAEGNG-IS 242  Histoplasma c...
Q0D1E0        191 HPA-GKAGLICITRSGVIR-FLYQ-NPDLRWTEIS--AELKNTSysd---------------rlLTHAALVATPGG--IL 248  Aspergillus t...
A1CQ63        193 HPV-NKAGLVCVTRSGTIR-LLYQ-NPDSRWAEIS--TELKNTGysd---------------rlLTHAALVSTQGG--VL 250  Aspergillus c...
CAK45284      191 HPA-NKAALLCITRSGSMK-LLYQ-NPDGRWDDIS--VDLKSTSysd---------------rlLSHAALVATQNG--IL 248  Aspergillus n...
A3LY88        266 VTAYDSV----TRNISTYSVTVDWgflvesaKRQKVDPHYHTPKEEHKTPKLNVTRISASIPVPTflaaaEEEgmdmdkm 341  Scheffersomyc...
Q59PP6        311 VTAWDSL----SNDINVYSIDINWgflvesaKRQKLDQHYHTPKEAQKPPRLTLKKLHQMKPIQC-----FKEedgesqs 381  Candida albic...
EDK46979      284 ISAWDSL----TNTIFTYLVTIDWgfltesaKRQKTDPHFHTPKESQKPPTMHLKLIHQMTPEQ---------------- 343  Lodderomyces ...
Q75E72        267 IGVFSNV----AKSFAFYELLINW-------NVNTTNQAMFHD------PKLTLRHILRVRPDAlgp------------- 316  Eremothecium ...
Q08D69        218 ATCDGSS----TSPVQFYKVCVSV-------------VSEKCKIDTEILPSLFMRCTTDPARKD---------------- 264  tropical claw...
Q16K67        235 AVGNGDSksanSNMIQCFRVAVKQ-------------REETLEINSTALPSFFLAEGMGKDLKE---------------- 285  yellow fever ...
XP_001541319  243 IAAYST-----YGKLYFYRIQVKW-------DPPEWDLTMKPGGGPVAFPTPAFQILHTKTEILS-----AIFhpqahdv 305  Histoplasma c...
Q0D1E0        249 VVTHS-A----CQKICFYRLQINW-------TPPQWDQSQMKQ-GSNQFPVPSFRFMHSKVEVPY-----DIPmsrapaq 310  Aspergillus t...
A1CQ63        251 VATHSA-----CQKLCLYRVQIAW-------NPTQYDPGQQKP--PAPWPVPSFRFLHCKVESLC-----DVIgtnrnpg 311  Aspergillus c...
CAK45284      249 VATYS----------------INW-------NPPQWDPAQQPKQTPPQFPVPSFRFTHSKVETSC-----TVPgmhrndg 300  Aspergillus n...
A3LY88        342 dvdadsedgnqpsyQIGSLASIDIISAGAEKDSS-----LDILISYTfedg-------sgiaSSTIYRYSLSEES----- 404  Scheffersomyc...
Q59PP6        382 qs----vvpemgklKVEELSSIDIISSNPDPKSG-----LSILITYG---------------SSIIYRYALEKSDssntt 437  Candida albic...
EDK46979      344 -----------------GLTSIDIISANPEKSSQ-----ASILWTY----------------GTTVYRYQITDTA----- 380  Lodderomyces ...
Q75E72        317 ------------ngELLKLENFHVISKTALPGTR-----PEILISYNilg----------teRSLVRRFQMVLSNpdm-- 367  Eremothecium ...
Q08D69        265 --------------KFPAVTHLKFLARDMS---------EQVLLCASnq------------cSSIAECWSLRKEGlp--- 306  tropical claw...
Q16K67        286 ----------------LRVAHVQWVFSEDA---------DSLIVASNht-----------ggGCFVEQWELTEES----- 324  yellow fever ...
XP_001541319  306 dy---itgfpspngSIYNLTHLEIITAPQAVPGTqaatgPCIIAVASipaqsqlgqpppsgpSSILVRWQLDTMA----- 377  Histoplasma c...
Q0D1E0        311 ns----ehltpppnPLYRLTHLDAILATQETATN-----PWVVAVFSisprvspdhpqqqgpPSIIVRWQLESTP----- 376  Aspergillus t...
A1CQ63        312 dn----qglpsftnSVYGLTRLDIILPALDNPAGst-stPWIVAVYSsplhatpdhpqqqspASVIVRWQLDTGA----- 381  Aspergillus c...
CAK45284      301 eep--dmmhqsisnPLYTLSRLDIILPASDNAAGtt-anPWIVAVFStppqatpdhpgpqgpASVIVRWQLDTAA----- 372  Aspergillus n...
A3LY88        405 -------ELISSAFGELGVRKNVTAP-ANSPTVQTVtlqDKLIRSGTIQSITTALSDY----------FILLYYLDGHVD 466  Scheffersomyc...
Q59PP6        438 sggetskNPISQAFYNLGVEKKIDWK-GDDSSVRLVf-kDKLMRRGQIESIINGFLDL----------SSLIIYKDGTVD 505  Candida albic...
EDK46979      381 -------NLIHEAFVELGRRQGVTGElRSVKTIDLV---DKITRLDPIQSIASGPSDM----------YAVIYYRNGKIE 440  Lodderomyces ...
Q75E72        368 ----vflSSLGLAITALHNNHS-----VLRYSMKHV---QDLTFDSKIMDIQSHSLDA----------LVCFRLHNGRFQ 425  Eremothecium ...
Q08D69        307 -----lnNIFQQLSPAVSDKQPMILKwRILSATNELervSAVALPKLPISLTNTDIKVasetkfypglGLALAFHDGNVQ 381  tropical claw...
Q16K67        325 -------TPIHKLFQSNKNEPFKTLLwVSK---------SQYMYTSKVIKICTTKLNFls------ssFVYLAMSDNSIH 382  yellow fever ...
XP_001541319  378 -------QSLHPNFDNVVSKNTASSP-KPKIIFRKL---DDIYFDRYVVSIDYMEAGS----------VLAITQDDSSIS 436  Histoplasma c...
Q0D1E0        377 -------QVLHPKFDEVVSKKSNVQI--------------------------KTEYGN----------VVAVVYDDSSIS 413  Aspergillus t...
A1CQ63        382 -------VTLHPKFDEVGSKKSSAQM-KPKLELRRL---EDIYSDRYAISIDQIEYGN----------VLAITYEDGSIV 440  Aspergillus c...
CAK45284      373 -------FTLHPKFDEMAAKRNSTQI-KPRPVLRRL---EDIYSDRYVISVDQIEYGN----------VVAITYDDSSVS 431  Aspergillus n...
A3LY88        467 VVDRNSMKIVNNS-------------DDTNLPPKTISSIFDVGFNFPKId-----------------nSSNLIMAVSPNL 516  Scheffersomyc...
Q59PP6        506 VVDTTSKQIVNNSknnnsvtgdemelDNNDYPPKLISNLFDQGFQFPKIs-----------------hKNRLVLAISPTM 568  Candida albic...
EDK46979      441 ILDAVEWEPV----------------GSKEYPPTTISTMFDLGYGFPSVgkeeqdhttknqnqnqnqnQNQLMMAVSPNL 504  Lodderomyces ...
Q75E72        426 LYNRHTWAVESETad---------akQIGGYTKDTIISIFGSGFNYPLLpp----------------aDAIEWCAISPSS 480  Eremothecium ...
Q08D69        382 IVHRLSLQPMAVL-------------YGSSLRPSEEPSLKRQRSPTPCI--------------------HFKALQMSWTS 428  tropical claw...
Q16K67        383 CLQRDTLKRLTCTn-----------iVSIRDPNDHSSKQIKLGLKIGAI-------------------------DVTHLG 426  yellow fever ...
XP_001541319  437 FFEARSMRP-----------------ITENEDDNIVTSMPNAGFTFPID------------------------------- 468  Histoplasma c...
Q0D1E0        414 FYDANTMTV-----------------CHGFGDAETVTCLAQAGFHYPAY-------------------ATGLSISFSPSG 457  Aspergillus t...
A1CQ63        441 FHDPKTMAV-----------------FNGVDDTNTVTSLAQAGFHYPPE-------------------ASGLHMAFSPNA 484  Aspergillus c...
CAK45284      432 FYDPKTMAL-----------------FNGVDDANTVTGLAQAGFHYAPDas----------------gCQGQHVSFSPSA 478  Aspergillus n...
A3LY88        517 TSVAYADFKGGst--rLNLKVFEKEKYLGISPKEL------FATSVGFAFRHAYACYTNTCSDDLVALIQTEIVR--LQI 586  Scheffersomyc...
Q59PP6        569 SSIVYTEIYGEtv--nLQLKPLERIDNFGTNSHDL------YYTSVAFAHRYAFALYTSTCSDDLLLLIQSEINR--IKD 638  Candida albic...
EDK46979      505 TSIVYTEIYGAdenshLILKTAEKVRNVGVSPKEL------LITSAGFAYRHAYACYSNTCSDDLVLLIEAEIDR--VKQ 576  Lodderomyces ...
Q75E72        481 GGII------------LKLKCKPQPTFYALEQSVLtdpsrdIVHATAFAFEFVRFNNMIHSGEDLAIAAKTHVFR--LQR 546  Eremothecium ...
Q08D69        429 LALVGLDTQGK----------LSMLRVSPSMGHSLdm--stSLRHLLFLLEYCMVTGYDWW--DILLHVQPGMVHnlVEK 494  tropical claw...
Q16K67        427 HLFVTLDTFGQlyvyrCNFMCQDQLGTPA------------LIVQTVNLLEYCLVTGLDSL--DILLTLKTQILEnvLER 492  yellow fever ...
XP_001541319  469 -------------------------------------------ASAALALGYVRACGSDASADDILTVI--------VRQ 497  Histoplasma c...
Q0D1E0        458 CNAVMLDSEGQ-----VQLRCMEHA--YGAESGLF------DQTIASLTMAFCRAVGSDMNSDDILVIL--------RQQ 516  Aspergillus t...
A1CQ63        485 CAAVMLDAEGQ--------TQLRLTEHTYGAEGGLhdenkySAAIAALTLAFCRGCGSDVNIDDVILIL--------VRQ 548  Aspergillus c...
CAK45284      479 CAAVMLDSDGQ---------------------------------THLRVMEHSYGAENGLYDENAQI------------- 512  Aspergillus n...
A3LY88        587 SLQKTITdkphniemiikKFVESIVSESHKAINFQLDAfNKESVDKLLS-NPPLQKLL----SLQLVLGELQD-----KN 656  Scheffersomyc...
Q59PP6        639 AVDGDTItrnk----lgkQLCDSVIIECHKAINFHLDTiTKESLDKLLSnNASLQKLL----SLQLILGEFQQsshfpNN 710  Candida albic...
EDK46979      577 TLSKQMPdkqenvnlivkKFIETIISESHRSINFQLDAfSKESVDKLLS-NPPLQKLL----SLQHILGEAQG------N 645  Lodderomyces ...
Q75E72        547 LSEERAV-----------NFIASVIGAILSLYGIHFDG-PKEILEKLLQ-SKAIQKIF----LLQMELGSHLK------N 603  Eremothecium ...
Q08D69        495 LNEEYTRqnaalqqvlstRILAMKASLCKLSQTTVTRVcDYHAKLFLISiSCTLKSLLrphvLNTPDKSPGDRlteicNK 574  tropical claw...
Q16K67        493 LTENFHRqppnvqqyyyvNFLTMKIALYRLSISGQQKAhDLSNLLILHSiLIAFKSLLrpsdLTSHDKGPAENla-mvLS 571  yellow fever ...
XP_001541319  498 LNPGAE------------TFVTEVYSILFMSVDFTEH-------DKLVN-HQSIQKGL----TMQAMLGFRSRf---qPR 550  Histoplasma c...
Q0D1E0        517 LSADAQS-----------MFIHGAYRALPVNCEFTLEG------DKLLS-NHALKERK----ENRLTLHP---------- 564  Aspergillus t...
A1CQ63        549 LSSEAQI-----------NFINEVYRALSVNCNFTMEQ------DKLMN-HIYIPRCL----SLQAALGFKDKy---tPR 603  Aspergillus c...
CAK45284      513 ------------------TFINEVYRALPINCNFTVEQ------EKLMN-HPYIPKCL----SIQAALGFADKy---kPR 560  Aspergillus n...
A3LY88        657 SIVSDIAWIVLNLRSTSFGIMFSLSSIYRQISKkkpte-----dslqdSITRGECIMSLVGNVKWLIDLMVYINQELLQL 731  Scheffersomyc...
Q59PP6        711 YVVPDIAWIVLNLRSASLGIMFTLSSIYRQVSKkkpse-----dtlqdSITRGECIMSIIGNFKWLIDLLVYLNQELLQL 785  Candida albic...
EDK46979      646 TVMSDIAWLILNLRSTNFGIMFTLSSIYRQISKkkpse-----dtmqdSITRGECILSLIGNIKWLIDLMAYFNQELMQL 720  Lodderomyces ...
Q75E72        604 KNVYSMAYASMKLRSINLAMNGVARNVHAMIQHtavvnslpngrafqfAFSKQDLIYSLIPSVNWFVSFVTFLTQQLIML 683  Eremothecium ...
Q08D69        575 FTDTDIDKVMINLKTEEFVLDM-------------------------------PTLQSLQQLIQWLGDFVLYLLASL--- 620  tropical claw...
Q16K67        572 ESVPDVDKVLLNVEAKEFTMER-------------------------------PTLQSLQQLIQWVADLALNILAKL--- 617  yellow fever ...
XP_001541319  551 TSSSAVSWIILNIRQIMVLLLTFSHYLKSGRDF---------------TPSEPEALHMILGNIKWILDLAKYLVNDLFEI 615  Histoplasma c...
Q0D1E0        565 -----------------------------------------------------EAIRMVLGNTKWLLDFLQYTLNEFLEL 591  Aspergillus t...
A1CQ63        604 SSPSAIPWAILQLRHASVLYAFFFQYNKGAPTE----------------SHDPDVLRMVLGNTKWALEFSFYVSNELFDL 667  Aspergillus c...
CAK45284      561 SFASSVSWSILQLRHAAILYPFFFQYNKGIQAEp---------------------------------------------- 594  Aspergillus n...
A3LY88        732 sysk------qdsSNSKLTIKNSIALPIILSKVPRLFLMYALSSIGRTHEILKKLHKDLSeasKLFTPMKESLNRYFtic 805  Scheffersomyc...
Q59PP6        786 iyvknnflnngntTTSKLTLSNSIVLPLILNKVSRLFLMYAISAMGRTHEILKKLHKDLTeanKLFAPMKESLNRYFsis 865  Candida albic...
EDK46979      721 tyf-------kndSRSELDLSNSIVLPVILSKVPRLFLMYAISSMGKTHEILKKLHKDLAesnKLFKPMKESLNRYFtif 793  Lodderomyces ...
Q75E72        684 -------------VNNPMDNTHSLVLGILSCITTRHLMLKVILELKNMIGLITKFPETTY---TVLNESSRFLRKAL--- 744  Eremothecium ...
Q08D69        621 ----------------PNQG---------SSVRPGHSFLRDGASLGTLREMMVMI--------RIWGLLKPSCLPVY--- 664  tropical claw...
Q16K67        618 ----------------------PESRSFMSNKSQGYDISKDIIALNSIRELLVMI--------RIWGLLNPQCLPVF--- 664  yellow fever ...
XP_001541319  616 edtip---pdrnlFSLPSKTYESPSLILVLSSVPRSFLRHIFRYLSRFPLAFKAAS-------NLSGESYQLFASINnti 685  Histoplasma c...
Q0D1E0        592 anefesipsdaetVSQKLKTIRSLPLMVILSGLPRSLLRFIGRALRGIYASYSTL--------PLIGDSRVYYAEICqii 663  Aspergillus t...
A1CQ63        668 adefesmasdqeaFTQKLKSTTSLPLIILLSSMSRAFLRFICRGLRGIHAGYATAA-------PLTGDARVYYAEIYqtl 740  Aspergillus c...
CAK45284      595 --------------HDPVKTTNSLALIILLSSMSRAFLRFICRGLRGIHAGYTNA--------SLGGDSRLQYAEICqal 652  Aspergillus n...
A3LY88        806 NNSPLTLSLFENFLRECDALITKE----------------QSI-RLAGKEKgyslkvEQKLVCQG-----------ELTE 857  Scheffersomyc...
Q59PP6        866 NNSPITVNLFESYLRECDALLNKEvpqkiltannsingnvNGNsGTSTNKPysalkfEQKLLIKGidvnddndsstKISN 945  Candida albic...
EDK46979      794 NNAPLTLNLFENYLRECDALVTKE----------------MATkGSLKIEQ---------SLVFG-----------IIPS 837  Lodderomyces ...
Q75E72        745 GDSPVNLEKFEVFLNEINNKFLSL----------------LDDhGAQSMDR------EPSFMVKA-----------EIPP 791  Eremothecium ...
Q08D69        665 TATSDTQDSMSLLFRLLTRLWLCC----------------RDEsHPCDPDE--------SLIDEC-----------CLLP 709  tropical claw...
Q16K67        665 SRSADNLDILGTLFRLLTKLSLNP----------------NEP--------------DDLLLDEC-----------CLLP 703  yellow fever ...
XP_001541319  686 EQSSLKPDVCEKMLTHIDSLVTRS----------------YEAaGFGNAERna---pEREMLITC-----------SIPP 735  Histoplasma c...
Q0D1E0        664 DSLPVRLDVYDKFLSEAEAAAKKS----------------YMLvGIQNPDRsg---aEKELLLNA-----------RIPQ 713  Aspergillus t...
A1CQ63        741 ENSPVRIDAYEKFLAGVDSAVRHA----------------YHSaGFGDAERpg---pEKELLVNA-----------RVPP 790  Aspergillus c...
CAK45284      653 DATPARIDVYEKFLSAVDSAVRHA----------------YHGaGFGDTERpg---pEKELLVNA-----------RIPP 702  Aspergillus n...
A3LY88        858 D---MEQIGKILIDRH-AVNINRDMKVSDLYFYDVDWLDIG-VNKRSARTSKGLSETVIypssqlkpkmiprlqysdkec 932  Scheffersomyc...
Q59PP6        946 Ti--IEELSNMILDRY-SISISRETKLSELMFYDTDWLNIGiNKKEVPSYTIDALRKLI--------------------- 1001 Candida albic...
EDK46979      838 E---VQDLAKTLVERY-SISIARESKVPDLFFYDTEWLNLG-NESKNKNINNQLGNNIVyn------------------- 893  Lodderomyces ...
Q75E72        792 A---LGHVREFLLSFA-GSALLAQTNLAEVFFASTHNLRIF-DHQHFHPSVANLLQPPEkglvvddailpdac------- 859  Eremothecium ...
Q08D69        710 SqllIPNMDWLPLGNG-IISRLQSKLPLRLQFGKPPVAPSY-ASVQYEAYTRSPTq------------------------ 763  tropical claw...
Q16K67        704 NqvlIPQLQYVPSRTMiASPLLPHVTLPVMCDYGVEN-----ESLKFCPEVPIVEGGLSnd------------------- 759  yellow fever ...
XP_001541319  736 V---LQPAVMSILTETmPLIVRSEVDRMALALYDYSWLGIG-DDKRTELFKRTHDVDILk-------------------- 791  Histoplasma c...
Q0D1E0        714 S---LIHAVTVLFQHS-IPALRPEIDCMAIYLSDYSWLGLG-TDPRAEMYRRTRDVDIVkklp----------------- 771  Aspergillus t...
A1CQ63        791 V---LVSAVATILRQT-VPALKSEIDRITIYMGNYSWLGLA-HDRRTEMYRRTRDVDIIkkiplrslgp----------- 854  Aspergillus c...
CAK45284      703 V---LVAAVSTILRQT-VPGLKSEVDRMAIYMHDYSWLGFG-SDLRSELYRRTREVDIIkktpirmt------------- 764  Aspergillus n...
A3LY88        933 idslrkiiisvdmnqitgktdtsrNGTTNHKAAIANDKIAklRKCTRCRSVSLVADplvfdapsTIGL-----WTMVFQR 1007 Scheffersomyc...
Q59PP6       1002 ------------------------ISDSSTSTSLAKGEKL--RVCTRCRAVSLVGD--------VTGL-----WTMVFQR 1042 Candida albic...
EDK46979      894 -----------------------nGVDALRKVNIFDKV----RRCTRCRSVSLVTDplvfeapsTIGL-----WTMVFQR 941  Lodderomyces ...
Q75E72        860 ----------rgsssfspldyddiSSEWVDMSALVRI-----KRCVRCGCVTRAGNpvaknntiLETSivtkrWTALYSR 924  Eremothecium ...
Q08D69        764 -----------------------pKIDHLRRLHLGTFPTEpcKSCTRCGCVTMLKSpnk--ataVKQ------WEQRWIK 812  tropical claw...
Q16K67        760 -----------------------nVIDSVMYLQLGRRPPSl-RRCTRCGSCSSVVSvak--taaMKA------WEQRWID 807  yellow fever ...
XP_001541319  792 -----------------------kNVNKLPDPTVAK------RRCVRCCEVSEDTWlprs-asmYRLI-----GKIGVLR 836  Histoplasma c...
Q0D1E0        772 ---------------------lrpVGRDERQEGKHNGHGQmrRRCVRCCGMLCGPYpsrt-hvsFRMM-----YKTGLLR 824  Aspergillus t...
A1CQ63        855 --------------ytevdaapsgKTNAQGPPQQPQPQQQrrRRCVRCCEISGDTHpprs-llsFRMI-----AKLGLLR 914  Aspergillus c...
CAK45284      765 ----------------iaqgsngpQLGKPNNQGVLR------RRCVRCCDVSEGTYpprs-vlaFRMI-----FKLGHLR 816  Aspergillus n...
A3LY88       1008 TCICGNAWVN 1017 Scheffersomyces stipitis CBS 6054
Q59PP6       1043 TCMCGNAWVN 1052 Candida albicans SC5314
EDK46979      942 TCICGNAWVN 951  Lodderomyces elongisporus NRRL YB-4239
Q75E72        925 YCQCTGLLYE 934  Eremothecium gossypii ATCC 10895
Q08D69        813 TCLCGGLWRK 822  tropical clawed frog
Q16K67        808 KCRCNGFWRL 817  yellow fever mosquito
XP_001541319  837 TCVCGGTFAM 846  Histoplasma capsulatum NAm1
Q0D1E0        825 YCLCGAAWMV 834  Aspergillus terreus NIH2624
A1CQ63        915 SCVCGGMWTL 924  Aspergillus clavatus NRRL 1
CAK45284      817 SCICGGMWTL 826  Aspergillus niger
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