8JC0,8Y81


Conserved Protein Domain Family
TCR_zetazeta

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pfam11628: TCR_zetazeta (This model is not part of the current CDD release)
T-cell surface glycoprotein CD3 zeta chain
The incorporation of the zetazeta signalling module requires one basic TCR alpha and two zetazeta aspartic acid TM residues. The structure of the zetazeta(TM) dimer consists of a left-handed coiled coil with polar contacts. Two aspartic acids are critical for zetazeta dimerization and assembly with TCR.
Statistics
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PSSM-Id: 519810
Aligned: 8 rows
Threshold Bit Score: 50.0196
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
8JC0_a        28 DPKLCYLLDGILFIYGVILTALFLRVKFSRS 58  human
XP_015219528  27 DPRLCYILDGVLLIYGIIITALYFKDKFSKP 57 
Q4T375        12 DANVCYILDGILVMFGAILTILFCRLKMNDA 42  spotted green pufferfish
NP_001003171  21 EPQLCYILDAILFLYGIVLTLLYCRLKIQVR 51 
XP_003457835  27 DPQLCYILDGFLGIYGLIITGMFIKEKFFKS 57 
8Y81_C        21 EPQLCYILDAILFLYGIVLTLLYCRLKIQVR 51  Norway rat
XP_014352588  29 DPRLCYILDGILFIYGIVITALYLKNKLSAP 59  coelacanth
XP_011604612  27 DPRLCYILDVFLGVYGLVITGMLIREKFFRS 57  torafugu
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