Conserved Protein Domain Family
NdhS

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pfam11623: NdhS (This model is not part of the current CDD release)
NAD(P)H dehydrogenase subunit S
This family is found in Bacteria and Streptophyta includes members such as NdhS (NAD(P)H-quinone oxidoreductase subunit S). NdhS, also known as CRR31 (chlororespiratory reduction 31), is a subunit of the chloroplast NADH dehydrogenase-like (NDH) complex. It is also a subunit of the cyanobacterial NDH-1 complex. NAD(P)H-oxidizing subunits have not been found in chloroplasts or cyanobacteria, where ferredoxin is probably the electron donor. NdhS contributes to the formation of a ferredoxin binding site of NDH and is necessary for high affinity binding of ferredoxin. The cyanobacterial NDH-1 complex, also known as NADPH:plastoquinone oxidoreductase or type I NAD(P)H dehydrogenase, is involved in plastoquinone reduction and cyclic electron transfer (CET) around photosystem I. The chloroplast NDH is more similar to cyanobacterial NDH-1, which is believed to be the origin of chloroplast NDH, than to mitochondrial NADH dehydrogenase present in the same species. The NDH complexes of chloroplasts, however, contain many subunits that are absent from cyanobacterial NDH-1 complexes.
Statistics
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PSSM-Id: 519806
Aligned: 21 rows
Threshold Bit Score: 91.6048
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015224307   2 ILPGSKVTVTNVDDIYYRFEGLVQRITDDNAAVLFEGGNWDKLVTFRLSELE 53  Halothece sp. PCC 7418
Q7V9R5         8 ILPGSSVKVNNPSSIYNGYKGFVQRIAENKAAVLFEGGNWDKLLTIPINELE 59  Prochlorococcus marinus
CAK27039       4 ILPGSTVRVSDGRSIYNGYQGFVQRISGDRAAVLFEGGNWDKLVTLPLKTLT 55 
Q46IK8         8 ILPGTTVTVNNQDSIYNGYEGFVQRISGDKAAVLFEGGNWDKLLTLPLKDLK 59  Prochlorococcus marinus str. NATL2A
WP_012953866   3 ILPGTTVKIINSDDIYYCFEGLVQRVSDGKAAVLFEGGNWSKLVTFPLSEIE 54  Candidatus Atelocyanobacterium thalassa
Q8DL61        45 ILPGMTVKVTNPNDTYYQFQGIVQRITDGKVAVLFEGGNWDKLVTFQASELE 96  Synechococcus elongatus
XP_009389542 162 FLPGMIVIVKNPKSPFYMYSGVVQRVTDGKAGVLFEGGNWDKLLTFDLSELE 213
XP_002973360 166 LMPGMTVIVKNPKNPYYMYTGILQRVTDGRAGILLEGGCWDKMLAIELKDLE 217
WP_015195246   4 ILPGTTVKVINPDDTYYKFQGLVQRIDDNRVAVLFEGGNWDKLITFKLSELE 55  Stanieria cyanosphaera
1_pfamImport   1 ILPGSTVRVKNPADTYYRYEGLVQRVSDGKVAVLFEGGNWDKLITFRLSELE 52 
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