Conserved Protein Domain Family
Prion_bPrPp

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pfam11587: Prion_bPrPp 
Major prion protein bPrPp - N terminal
This family represents the N-terminal domain (1-30) of the bovine prion protein (bPrPp). The proteins structure consists of mainly alpha helices. BPrPp forms a stable helix which inserts in a transmembrane location in the bilayer, with the N -terminal (1-30) functioning as a cell-penetrating peptide.
Statistics
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PSSM-Id: 491962
Aligned: 5 rows
Threshold Bit Score: 47.916
Created: 15-Feb-2025
Updated: 28-Apr-2025
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
O46501         1 MVKshIGSWILVLFVAMWSDVGLCKKRPKP 30  dog
XP_003226790   1 MGKhqMTCWLAIFLLLIQANVSLAKKKPKP 30 
XP_003788084   1 MAR--LGCWMLVLFVATWSDIGLCKKRPKP 28 
XP_005320560   1 MVN--PGCWLLVLFVATLSDVGLCKKRPKP 28 
XP_003499061   1 MAN--LSYWLLALFVATWTDVGLCKKRPKP 28 
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