3BRC,3WB0,5D5P


Conserved Protein Domain Family
HcgB

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pfam11576: HcgB 
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FeGP cofactor biosynthesis protein HcgB, guanylyltransferase
This entry represents the guanylyltransferase component of the Iron-guanylylpyridinol (FeGP) cofactor biosynthesis protein HcgB. This family of proteins with unknown function appears to be restricted to Methanobacteria.
Statistics
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PSSM-Id: 402947
Aligned: 13 rows
Threshold Bit Score: 231.034
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3BRC_B            3 EDLIGKAYLESAEDRRRGDRSEEVEAIRKYIRSARRTVVPNWNAEKVDAINDVLRSFN----------LREAEHLQFNTN 72  Methanotherm...
jgi:Mvol_1086     5 NKIIKNSYIHSLENCRNGDQIEEIEAIQNVIKNSKKIVVATSNGKKFKVVKNIILKVLdnhcndnnqnNVNIEMLDICTN 84 
WP_011834103      7 DCCVSSAYSQSLNGTRLGDTAEETMSIREYIKSSRHIVVPNHDDRKIAVINSVLSSFG----------LPRAVHLCIPTN 76  Methanocorpu...
jgi:Metfor_0859   2 EDLIRGAYHESLAGARKGDTDAELEAIRHYIRGARTIIVPNRNTVKISVINTVLAEFG----------LPRAVHLHCDTN 71 
WP_013329923      4 EDFISKACIESSTGIRRGDKREETEGIREYILNSKTIVIPNCNDEKVAAVNEVLDELD----------LPKAGHLNIHTD 73  Methanolacin...
WP_016357636      4 EKMIKNAFEESENNCRFGDKIEEVHEIQTYIKNAKKIYVPNKNGIKVKVLNKVLKEYG----------LNEAHILKINTN 73  Methanobrevi...
WP_012955330      4 EESIRKASIQSYEGTRKGDTIEEIEAIQNYIRNA-KIVVPNKNGIKVEVINEVLAKFN----------IPPAEYLQVNTN 72  Methanobrevi...
jgi:Maeo_1291     4 nKIIKDAYLESITNKRCGDKIEELLYIQNKILNAKKIVVATNNKKKFDIINNILISLFkny----dkpLPTIEKLDLPTN 79 
3WB0_B            5 EEIIKKAFIESINNIRRGDKEEELKKIQEKIVNAKKIVVATNNQKKFKVIRDIMLRVC----------NAEIKMLDIDTR 74  Methanocaldo...
5D5P_D            4 ENTIKSAYEESLNNARFGDKIEEIDAIQSTIKSAKNVTVATSNEKKFKVVSDIISRIT----------DANISMLEIPTN 73  Methanococcu...
Q8TZB7            3 KETLLKAWWESWEGTRRGDEEREVEGLREYLTSADRLAVVTGNEDKLRAVNKVLRRFG----------LPEAEMIRVPTE 72  Methanopyrus...
jgi:Dester_1507   6 lELFKNAFLESLVGNRKGDKPEETALLRERILKG-KIGIVTNNKKKFTIAKKTISLFG----------IKNISQIEIPTE 74 
WP_013413848      4 EKLIKKAYVESVEGRRQGDKIKEVKEIQKYILNAKNIVVPNKTKEKVKAINEVLEKFG----------IQKAKHLKFYTD 73  Methanotherm...
3BRC_B           73 WADLTRXPAVTKALXALDISGADLVIARGRLGVPGSGSLLVIXDSRGRLLSAAXSPPHVIHSXEVREAVRSEXTHALERI 152 Methanotherm...
jgi:Mvol_1086    85 SADLTRMPALTKGLIAVDITDADLIIARGRLGIAGSGSLLLLMDGKGRILTGAMSPSSIIHKESIEHKMEFELLQALKKI 164
WP_011834103     77 SPDLTRTPAVSKALMALDITGADLVIARGRLGVPGSGSMLVIMDSRGRILSASLSPSHLYHAKSISDAVTHEMEEALVRV 156 Methanocorpu...
jgi:Metfor_0859  72 CCDISRMPALTKALMALDISGCDLVIARGRLGMPGSGSMLVILDNRGRILTAGLSPSHSIHKKPVELAVHDEMVMALERI 151
WP_013329923     74 SCDVSRMPAVTKALMALDMTDADLIIARGRLGVPGSGSMLVIVDCKGRLLSASISPSHHIHGKTVYQAVKDEMTDALSRI 153 Methanolacin...
WP_016357636     74 FADTSRIPALSKAYIALDQCDCDLIISRGRLGVPGSGSLLVFIDNKGRILTAGSSPSHAVTSKPLEEAVYMEAVEALEKV 153 Methanobrevi...
WP_012955330     73 YADFSRMPAIAKAMIAVDQSDADLVIARGRLGIPGSGSFLVFMDSKSRILTAATSPSHIIHNQPLEKTVYKETLEALKKV 152 Methanobrevi...
jgi:Maeo_1291    80 SVDLTRFPAINKGLIAVDTSDADIVIARGRLGAPGSGSMLIIMNNKGRCLSASLSPTSLIHKKDIEDAVKDELNEALERI 159
3WB0_B           75 FADLTRMPALTKGLIALDIEKADLYIARGRLGAPGSGSMLVILDEKGRVLTASLSPSSVIHKEDIEERIKKELIEALSRI 154 Methanocaldo...
5D5P_D           74 SADLTRMPALNKGLIAVDSSDADLIITRGRLGIPGSGSLLLIMDKKGRILTGSVSPSSIIHKNPIDKTVELELITALERI 153 Methanococcu...
Q8TZB7           73 MADATPCPAIFKAIMGVQVSDADVVIARGRLGVPGSGAMTVFMDARCRLLTAALSPPHVLHEMSVKEAMEREAEEALRRL 152 Methanopyrus...
jgi:Dester_1507  75 IFDLTEIPTLSKALAGRFFKNCNFYVARGRLGAPGSGALTIMIDEFGHVISAVTSPPHHLHKFSLETSVFLDIFRLLKRL 154
WP_013413848     74 ACDLNRTPAISKALMALDIVDCDLVIARGRLGVPGSGSMLVIMDSKGRILSAALSPPHIIHKKSVEKAVKDEMTTALKRI 153 Methanotherm...
3BRC_B          153 GF 154 Methanothermobacter thermautotrophicus str. Delta H
jgi:Mvol_1086   165 GI 166
WP_011834103    157 GF 158 Methanocorpusculum labreanum
jgi:Metfor_0859 152 GL 153
WP_013329923    154 GF 155 Methanolacinia petrolearia
WP_016357636    154 GF 155 Methanobrevibacter
WP_012955330    153 GF 154 Methanobrevibacter ruminantium
jgi:Maeo_1291   160 GI 161
3WB0_B          155 GI 156 Methanocaldococcus jannaschii DSM 2661
5D5P_D          154 GI 155 Methanococcus maripaludis S2
Q8TZB7          153 GM 154 Methanopyrus kandleri
jgi:Dester_1507 155 GF 156
WP_013413848    154 GL 155 Methanothermus fervidus
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